Paid Clinical Trials in Lexington, KY

As of July 2026, 450 paid clinical trials are recruiting in Lexington, Kentucky. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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408 clinical trials

Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

for Non-Arteritic Anterior Ischemic Optic Neuropathy

Sites in Lexington +17 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 50 - 80

Code: NCT07453888·Phase 3·Recruiting·Listed Mar 2026

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AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for Hernia

Sites in Lexington +11 more locations

Sponsor: Tissium

Sex: All·Age: 22+

Code: NCT07277946·Recruiting·Listed Dec 2025

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A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Atezolizumab

Sites in Lexington +9 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155174·Phase 2·Recruiting·Listed Sep 2025

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A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

for Advanced Liver Cancers

Sites in Lexington +13 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04524871·Phase 1, Phase 2·Recruiting·Listed Aug 2020

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DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

for Small Cell Lung Carcinoma

Sites in Lexington +11 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT05882058·Phase 2·Recruiting·Listed May 2023

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A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

for Diffuse Large B-cell Lymphoma (DLBCL)

Drug: Odronextamab

Sites in Lexington +17 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06091865·Phase 3·Recruiting·Listed Oct 2023

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Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

Sites in Lexington +16 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting·Listed Jul 2025

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Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for Atrial Fibrillation (AF)

Sites in Lexington +17 more locations

Sponsor: Arga Medtech SA

Sex: All·Age: 18 - 80

Code: NCT06784466·Recruiting·Listed Jan 2025

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Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

for Chronic Low-back Pain

Sites in Lexington +15 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06827262·Recruiting·Listed Feb 2025

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A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

for Chronic Migraine in Children

Sites in Lexington +9 more locations

Sponsor: H. Lundbeck A/S

Sex: All·Age: 12 - 17

Code: NCT04965675·Phase 3·Recruiting·Listed Jul 2021

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Lead-212 PSV359 Therapy for Patients With Solid Tumors

for Pancreatic Ductal Adenocarcinoma

Sites in Lexington +10 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06710756·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

for Invasive Mold Infections

Sites in Lexington +18 more locations

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT06925321·Phase 3·Recruiting·Listed Apr 2025

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

for Candidemia

Sites in Lexington +21 more locations

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT05421858·Phase 3·Recruiting·Listed Jun 2022

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A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

for SST2-positive Neuroendocrine Neoplasms

Sites in Lexington +21 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07129252·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

for Recurrent Melanoma (Skin)

Drug: Nivolumab

Sites in Lexington +11 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05655312·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

for Hemolytic Disease of the Fetus and Newborn

Drug: Nipocalimab

Sites in Lexington +17 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT05912517·Phase 3·Recruiting·Listed Jun 2023

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Vivistim Registry for Paired VNS Therapy (GRASP)

for Upper Extremity Problem

Sites in Lexington +14 more locations

Sponsor: MicroTransponder Inc.

Sex: All·Age: 22+

Code: NCT05301140·Recruiting·Listed Mar 2022

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A Study to Assess the Safety and Risk of Hypersensitivity Reactions of Sulbactam-durlobactam in Adults With Acinetobacter Baumannii-calcoaceticus (ABC) Complex Infection

for Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

Sites in Lexington +11 more locations

Sponsor: Innoviva Specialty Therapeutics

Sex: All·Age: 18+

Code: NCT06746883·Recruiting·Listed Dec 2024

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Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

Sites in Lexington +15 more locations

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting·Listed Mar 2025

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A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

for Lupus Erythematosus, Systemic

Sites in Lexington +18 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06581198·Phase 2·Recruiting·Listed Sep 2024

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A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine

for Migraine

Sites in Lexington +13 more locations

Sponsor: H. Lundbeck A/S

Sex: All·Age: 6 - 17

Code: NCT05164172·Phase 3·Recruiting·Listed Dec 2021

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A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

Sites in Lexington +21 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting·Listed Oct 2024

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Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for Neuroendocrine Tumors Unresectable

Sites in Lexington +18 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05636618·Phase 1, Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

WRAP North America

for Venous Stenosis

Sites in Lexington +14 more locations

Sponsor: Merit Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT06807099·Recruiting·Listed Feb 2025

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Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

for Degenerative Disc Disease

Sites in Lexington +18 more locations

Sponsor: VIVEX Biologics, Inc.

Sex: All·Age: 22 - 85

Code: NCT06778447·Recruiting·Listed Jan 2025

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A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

for Ph+ ALL

Sites in Lexington +15 more locations

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT06051409·Phase 3·Recruiting·Listed Sep 2023

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Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

for Atrial Fibrillation (AF)

Sites in Lexington +11 more locations

Sponsor: Vektor Medical

Sex: All·Age: 22+

Code: NCT06935591·Recruiting·Listed Apr 2025

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Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

for Hepatocellular Carcinoma (HCC)

Sites in Lexington +12 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT06726161·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for Non-Small Cell Lung Cancer

Drug: Livmoniplimab

Sites in Lexington +16 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06236438·Phase 2, Phase 3·Recruiting·Listed Feb 2024

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Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

for Myasthaenia Gravis

Sites in Lexington +22 more locations

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT06799247·Phase 3·Recruiting·Listed Jan 2025

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Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

for Carcinoma, Non-Small Cell Lung

Drug: Osimertinib

Sites in Lexington +8 more locations

Sponsor: Genprex, Inc.

Sex: All·Age: 18+

Code: NCT04486833·Phase 1, Phase 2·Recruiting·Listed Jul 2020

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A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for Advanced Solid Tumor

Sites in Lexington +20 more locations

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06778863·Phase 1·Recruiting·Listed Jan 2025

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

Sites in Lexington +10 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting·Listed Sep 2024

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CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for Relapsed/Refractory Multiple Myeloma

Sites in Lexington +15 more locations

Sponsor: Caribou Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05722418·Phase 1·Recruiting·Listed Feb 2023

Apply to this trial

CERAMENT™| Bone Void Filler Device Registry

for Orthopedic Disorder

Sites in Lexington +10 more locations

Sponsor: BONESUPPORT AB

Sex: All·Age: 18+

Code: NCT04244942·Recruiting·Listed Jan 2020

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

Sites in Lexington +21 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting·Listed Jul 2023

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cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for Brain Cancer

Sites in Lexington, Elizabethtown +14 more locations

Sponsor: Adela, Inc

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05366881·Recruiting·Listed May 2022

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Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

for Pulmonary Nodule, Solitary

Sites in Lexington, Louisville +20 more locations

Sponsor: Veracyte, Inc.

Sex: All·Age: 29 - 85

Code: NCT06426628·Recruiting·Listed May 2024

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A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

for Asthma

Sites in Lexington +50 more locations

Sponsor: Sanofi

Sex: All·Age: 6+

Code: NCT07556159·Recruiting·Listed Apr 2026

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A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

for Extensive-stage Small Cell Lung Cancer (ES-SCLC)

Sites in Lexington +2 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07564401·Phase 1, Phase 2·Recruiting·Listed May 2026

Apply to this trial