Paid Clinical Trials in Lincoln, NE
As of June 2026, 166 paid clinical trials are recruiting in Lincoln, Nebraska. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Lincoln offers studies at sites including Saint Elizabeth Regional Medical Center for conditions such as Breast Cancer, Heart Failure, Non-Small Cell Lung Cancer, Schizophrenia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Lincoln
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·Clear filters·↓ Download CSVAbout research studies in Lincoln
Lincoln has approximately 166 recruiting research studies across a wide range of therapeutic areas. Nebraska hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Lincoln
Researchers run research studies in Lincoln, NE at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Saint Elizabeth Regional Medical Center | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Chronic Lymphocytic Leukemia | 28 |
| Cancer Partners of Nebraska | Breast Cancer, Stage IIIB Lung Cancer AJCC v8, Advanced Lung Non-Squamous Non-Small Cell Carcinoma | 15 |
| Bryan Heart | Obesity, Heart Failure, Heart Failure With Preserved Ejection Fraction | 10 |
| Bryan Medical Center | Acute Respiratory Distress Syndrome, Anastomotic Leak, Bowel Resection | 7 |
| Somnos Clinical Research | Focal Epilepsy, Amyotrophic Lateral Sclerosis, Clonal Mast Cell Disease | 5 |
| Alivation Research, LLC | Acute Treatment of Migraine, Alzheimer's Disease Psychosis, Depressive Disorder | 4 |
| Celerion | Healthy, Healthy Adult Male and Female Volunteers, Healthy Participants | 4 |
| NHO Revive Research Institute, LLC | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 4 |
| Nebraska Hematology Oncology | Gastroesophageal Junction Adenocarcinoma, Metastatic Gastric Adenocarcinoma, Solid Tumor | 3 |
| GSK Investigational Site | Chickenpox | 2 |
| Alkermes Investigational Site | Bipolar I Disorder, Idiopathic Hypersomnia, Narcolepsy Type 1 | 2 |
| Alkermes Investigator Site | Bipolar I Disorder, Idiopathic Hypersomnia, Schizophrenia | 2 |
| Cancer Partners of Nebraska - April Sampson Cancer Center | Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC), Non-Small Cell Lung Cancer | 2 |
| Celerion, Inc. | Healthy Participants, Schizophrenia | 2 |
| Kailera Clinical Site | Obesity, Obesity With Diabetes, Overweight With Diabetes | 2 |
| Nebraska Heart Hospital | Coronary Artery Disease, Heart Diseases, Coronary Artery Bypass Grafting | 2 |
| Nebraska Hematology and Oncology | Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma | 2 |
| Physician Research Collaboration | Autoimmunity, Inflammation, Osteoarthritis, Knee | 2 |
| University of Nebraska Medical Center College of Dentistry | Edentulism, Periodontal Inflammation | 2 |
| University of Nebraska-Lincoln | Alcohol Drinking, Cognitive Ability, General, Dietary Assessment | 2 |
| Midwest Children's Health Research Center | Healthy | 1 |
| Alivation Research /ID# 279464 | Bipolar I or II Disorder | 1 |
| Alivation Research, LLC. | Pediatric Migraine | 1 |
| Allergy Asthma & Immunology- Site Number : 8400044 | Atopic Dermatitis | 1 |
| Anthos Investigative Site 1066 | Atrial Fibrillation (AF) | 1 |
Active & Upcoming Studies in Lincoln (2026)
Recruiting trials in Lincoln grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (61 active studies)
- A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014) · Phase 3 · Merck Sharp & Dohme LLC
- Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer · Phase 2 · Genmab
Cardiovascular (15 active studies)
Diabetes & metabolic (10 active studies)
Mental health & behavior (9 active studies)
- A Study to Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults · Phase 1 · Otsuka Pharmaceutical Development & Commercialization, Inc.
- Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT) · Bristol-Myers Squibb
Neurology & pain (7 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Long-term Safety and Tolerability of BHV-7000 · Phase 2 · Biohaven Therapeutics Ltd.
Pediatric (1 active study)
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in Lincoln
- Breast Cancer (6 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (5 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Non-Small Cell Lung Cancer (5 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Schizophrenia (5 active studies). Schizophrenia research tests muscarinic agonists, long-acting injectable antipsychotics, and cognitive remediation therapies.
- Obesity (4 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Coronary Artery Disease (3 active studies). Coronary artery disease research evaluates lipid-lowering therapies, anti-inflammatory agents, and new revascularization devices.
Leading research sponsors in Lincoln
- SWOG Cancer Research Network
- AstraZeneca
- AbbVie
- Merck Sharp & Dohme LLC
- Pfizer
Local regulations and guidelines
Clinical trials in Nebraska are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Nebraska research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Lincoln. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Lincoln
Hipa.ai aggregates every recruiting study in Lincoln from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Lincoln?
There are approximately 166 recruiting clinical trials in Lincoln, Nebraska listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lincoln pay participants?
Most recruiting trials in Lincoln compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lincoln?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lincoln?
The most common conditions under active study in Lincoln include Breast Cancer (6), Heart Failure (5), Non-Small Cell Lung Cancer (5), Schizophrenia (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lincoln?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lincoln on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lincoln?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lincoln?
Recruiting research sites in Lincoln include Saint Elizabeth Regional Medical Center, Cancer Partners of Nebraska, Bryan Heart, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lincoln right now?
The largest active categories in Lincoln are Cancer & tumors (61), Cardiovascular (15), Diabetes & metabolic (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.