Paid Clinical Trials in Grand Island, NE
As of July 2026, 49 paid clinical trials are recruiting in Grand Island, Nebraska. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Grand Island offers studies at sites including CHI Health Saint Francis for conditions such as Breast Cancer, Migraine, Non-Small Cell Lung Cancer, RISS Stage I Plasma Cell Myeloma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Grand Island
Trials by drug in Grand Island
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Newly added in Grand Island
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
46 clinical trials
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease
A Study of BLB-201 RSV Vaccine in Infants and Children
Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
Family Communications After Genetic Testing
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
Mobile Health for Adherence in Breast Cancer Patients
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
Top Research Study Locations in Grand Island
Researchers run research studies in Grand Island, NE at 23 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| CHI Health Saint Francis | RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma, Acute Lymphoblastic Leukemia | 18 |
| Velocity Clinical Research, Grand Island | COVID-19 SARS-CoV-2 Infection, Clostridioides Difficile Associated Disease, Healthy | 8 |
| Grand Island Pain Relief Center | Chronic Pain, Diabetic Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN) | 3 |
| Nebraska Cancer Specialists | Breast Cancer, Locally Advanced Non-Small Cell Lung Cancer (NSCLC), Metastatic Non-Small Cell Lung Cancer (NSCLC) | 3 |
| Grand Island Regional Medical Center | Healthy, Lumbar Spinal Stenosis | 2 |
| Nebraska Cancer Specialists St Francis Grand Island | B Cell Lymphoma, HR+/HER2- Breast Cancer, Mantle Cell Lymphoma | 2 |
| CHI Health Nebraska Heart | Percutaneous Coronary Intervention, Peripheral Endovascular Intervention | 1 |
| CHI Health St Francis | Healthy | 1 |
| CHI Health St. Francis | Lumbar Spinal Stenosis | 1 |
| GSK Investigational Site | Colonic Neoplasms, Neoplasms, Colon | 1 |
| Grand Island | Endometriosis, Uterine Fibroids | 1 |
| Grand Island Surgery Center | Lumbar Spinal Stenosis | 1 |
| Heartland Radiology | Lumbar Spinal Stenosis | 1 |
| Local Institution - 007-590D | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
| Nebraska Cancer Specialist | KRAS G12C-mutated Solid Tumors, Lung Cancer, KRAS, NRAS, HRAS-mutated NSCLC, Lung Cancer Stage IV, Advanced Solid Tumor, Cancer | 1 |
| Nebraska Cancer Specialists (NCS) - Regional Cancer Center - St Francis Location | Follicular Lymphoma (FL) | 1 |
| Oncology Hematology West - Grand Island | Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer | 1 |
| Oncology Hematology West, PC dba Nebraska Cancer Specialist | Breast Neoplasms | 1 |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists | DLBCL, Diffuse Large B-Cell Lymphoma | 1 |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists - Grand Island | Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC), Non-Small Cell Lung Cancer | 1 |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists - Regional | Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC), Non-Small Cell Lung Cancer | 1 |
| Total Body Pain Institute | Lumbar Spinal Stenosis | 1 |
| Tri City Research Center, LLC | Migraine | 1 |
Active & Upcoming Studies in Grand Island (2026)
Recruiting trials in Grand Island grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (27 active studies)
- A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) · Phase 2 · Bristol-Myers Squibb
- BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease · Phase 3 · BeOne Medicines
Vaccines (4 active studies)
- A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose · Phase 3 · Pfizer
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
Neurology & pain (4 active studies)
Mental health & behavior (1 active study)
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Cardiovascular (1 active study)
Common conditions studied in Grand Island
- Breast Cancer (2 active studies)
- Migraine (2 active studies)
- Non-Small Cell Lung Cancer (2 active studies)
- RISS Stage I Plasma Cell Myeloma (2 active studies)
- RISS Stage II Plasma Cell Myeloma (2 active studies)
- Acute Lymphoblastic Leukemia (1 active study)
Leading research sponsors in Grand Island
- Alliance for Clinical Trials in Oncology
- Pfizer
- SWOG Cancer Research Network
- AstraZeneca
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Grand Island?
There are approximately 49 recruiting clinical trials in Grand Island, Nebraska listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Grand Island pay participants?
Most recruiting trials in Grand Island compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Grand Island?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Grand Island?
The most common conditions under active study in Grand Island include Breast Cancer (2), Migraine (2), Non-Small Cell Lung Cancer (2), RISS Stage I Plasma Cell Myeloma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Grand Island?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Grand Island on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Grand Island?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Grand Island?
Recruiting research sites in Grand Island include CHI Health Saint Francis, Velocity Clinical Research, Grand Island, Grand Island Pain Relief Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Grand Island right now?
The largest active categories in Grand Island are Cancer & tumors (27), Vaccines (4), Neurology & pain (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.