Paid Clinical Trials in Lincoln, NE
As of July 2026, 129 paid clinical trials are recruiting in Lincoln, Nebraska. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Lincoln offers studies at sites including Cancer Partners of Nebraska for conditions such as Non-Small Cell Lung Cancer, Schizophrenia, Heart Failure, Healthy. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Lincoln
Trials by drug in Lincoln
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Newly added in Lincoln
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
122 clinical trials
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Assessment of CCM in HF With Higher Ejection Fraction
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Top Research Study Locations in Lincoln
Researchers run research studies in Lincoln, NE at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cancer Partners of Nebraska | Carcinoma, Non-Small-Cell Lung (NSCLC), Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung | 11 |
| Bryan Heart | Obesity, Heart Failure, Heart Failure With Preserved Ejection Fraction | 10 |
| NHO Revive Research Institute, LLC | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 9 |
| Bryan Medical Center | Acute Respiratory Distress Syndrome, Bowel Resection, Colon Procedures | 6 |
| Somnos Clinical Research | Allergic Conjunctivitis, Amyotrophic Lateral Sclerosis, Chronic Spontaneous Urticaria (CSU) | 5 |
| Celerion | Healthy, Healthy Adult Male and Female Volunteers, Healthy Participants | 5 |
| Midwest Children's Health Research Institute | Pneumococcal Disease, Healthy | 3 |
| Alivation Research LLC | Autism Spectrum Disorder, Bipolar Depression, Bipolar Disorder | 3 |
| Nebraska Hematology-Oncology | Non-small Cell Lung Cancer (NSCLC), Follicular Lymphoma (FL), Non-Small Cell Lung Cancer | 3 |
| Physician Research Collaboration, LLC | Cardiovascular Disease, Psoriatic Arthritis, Atopic Dermatitis | 3 |
| GSK Investigational Site | Chickenpox | 2 |
| Alkermes Investigational Site | Bipolar I Disorder, Idiopathic Hypersomnia, Narcolepsy Type 1 | 2 |
| Alkermes Investigator Site | Bipolar I Disorder, Idiopathic Hypersomnia, Schizophrenia | 2 |
| Celerion, Inc. | Healthy Participants, Schizophrenia | 2 |
| NHO Revive Research Institute | Cancer Weight Loss, KRAS G12C Lung Cancer, Non-Small Cell Lung Cancer | 2 |
| Nebraska Heart Hospital | Coronary Artery Disease, Heart Diseases, Coronary Artery Bypass Grafting | 2 |
| Nebraska Hematology Oncology | Gastroesophageal Junction Adenocarcinoma, Metastatic Gastric Adenocarcinoma, Solid Tumor | 2 |
| Saint Elizabeth Regional Medical Center | Anatomic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29, Estrogen Receptor Positive | 2 |
| University of Nebraska Medical Center College of Dentistry | Edentulism, Periodontal Inflammation | 2 |
| University of Nebraska-Lincoln | Alcohol Drinking, Cognitive Ability, General, Dietary Assessment | 2 |
| NHO Revive Research Institute LLC | Breast Cancer, Non-small Cell Lung Cancer | 2 |
| Nho - Revive Research Institute | Non-Squamous Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer | 2 |
| Midwest Children's Health Research Center | Healthy | 1 |
| Alivation Research | Bipolar I or II Disorder | 1 |
| Alivation Research, LLC | Treatment Resistant Depression | 1 |
Active & Upcoming Studies in Lincoln (2026)
Recruiting trials in Lincoln grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (41 active studies)
Cardiovascular (13 active studies)
Mental health & behavior (10 active studies)
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- A Study to Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults · Phase 1 · Otsuka Pharmaceutical Development & Commercialization, Inc.
Diabetes & metabolic (9 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes · Medtronic MiniMed, Inc.
Vaccines (2 active studies)
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
- A Study of BLB-201 RSV Vaccine in Infants and Children · Phase 1, Phase 2 · Blue Lake Biotechnology Inc.
Neurology & pain (2 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Long-term Safety and Tolerability of BHV-7000 · Phase 2 · Biohaven Therapeutics Ltd.
Common conditions studied in Lincoln
- Non-Small Cell Lung Cancer (6 active studies)
- Schizophrenia (6 active studies)
- Heart Failure (5 active studies)
- Healthy (4 active studies)
- Non-small Cell Lung Cancer (4 active studies)
- Breast Cancer (3 active studies)
Leading research sponsors in Lincoln
- Merck Sharp & Dohme LLC
- AstraZeneca
- Pfizer
- AbbVie
- Alkermes, Inc.
Frequently asked questions
How many paid clinical trials are currently recruiting in Lincoln?
There are approximately 129 recruiting clinical trials in Lincoln, Nebraska listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lincoln pay participants?
Most recruiting trials in Lincoln compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lincoln?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lincoln?
The most common conditions under active study in Lincoln include Non-Small Cell Lung Cancer (6), Schizophrenia (6), Heart Failure (5), Healthy (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lincoln?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lincoln on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lincoln?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lincoln?
Recruiting research sites in Lincoln include Cancer Partners of Nebraska, Bryan Heart, NHO Revive Research Institute, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lincoln right now?
The largest active categories in Lincoln are Cancer & tumors (41), Cardiovascular (13), Mental health & behavior (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.