Paid Clinical Trials in Lincoln, NE

As of September 2026, 129 paid clinical trials are recruiting in Lincoln, Nebraska. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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120 clinical trials

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Inflammation in Clear Aligners With and Without Attachments

for Periodontal Inflammation

1 location in Lincoln

Sponsor: University of Nebraska

Sex: All·Age: 14 - 35

Code: NCT07506993·Recruiting·Listed Apr 2026

Apply to this trial

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Lincoln, Bellevue +625 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Lincoln, Omaha +923 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

Apply to this trial

I-DECIDE After Bronchiolitis Hospitalization

for Bronchiolitis Acute

Sites in Lincoln, Omaha +58 more locations

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Months - 24 Months

Code: NCT07243652·Recruiting·Listed Nov 2025

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for Advanced Lung Non-Squamous Non-Small Cell Carcinoma

Drug: Bevacizumab

Sites in Lincoln +325 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04181060·Phase 3·Recruiting·Listed Nov 2019

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Lincoln +302 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

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Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

for Percutaneous Coronary Intervention

Drug: Inclisiran

Sites in Lincoln, Omaha +132 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06909565·Phase 4·Recruiting·Listed Apr 2025

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

Sites in Lincoln +25 more locations

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes

for Childhood Obesity Pevention

1 location in Lincoln

Sponsor: University of Nebraska Lincoln

Sex: All·Age: 3+·Accepts healthy volunteers

Code: NCT07160530·Recruiting·Listed Sep 2025

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Lincoln, Bellevue +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

Apply to this trial

Randomization of Single vs Multiple Arterial Grafts

for Coronary Artery Disease

Sites in Lincoln, Omaha +9 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18 - 70

Code: NCT03217006·Recruiting·Listed Jul 2017

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Lincoln, Papillion +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

Apply to this trial

Investigating the Effects of Beef Consumption on Cognitive and Brain Health

for Dietary Intervention

1 location in Lincoln

Sponsor: University of Nebraska Lincoln

Sex: All·Age: 19 - 24·Accepts healthy volunteers

Code: NCT06690892·Recruiting·Listed Nov 2024

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

Sites in Lincoln, Omaha +39 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting·Listed Oct 2019

Apply to this trial

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

Sites in Lincoln, Papillion +130 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Multi-Site Feasibility Testing of the Ventricular Assist Device Anticipatory Guidance Tool

for Ventricular Assist Device

Sites in Lincoln +1 more location

Sponsor: Bryan Heart

Sex: All·Age: 19+

Code: NCT06823583·Recruiting·Listed Feb 2025

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Motivations, Attitudes, and Perceptions Study

for Alcohol Drinking

1 location in Lincoln

Sponsor: University of Nebraska Lincoln

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT05873413·Recruiting·Listed May 2023

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

Sites in Lincoln +54 more locations

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting·Listed Nov 2020

Apply to this trial

Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged

for Edentulism

1 location in Lincoln

Sponsor: University of Nebraska

Sex: All·Age: 14 - 80

Code: NCT06943846·Recruiting·Listed Apr 2025

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Association of Periodontal Inflammation on Immune Response in Wound Healing

for Inflammation of Mouth

1 location in Lincoln

Sponsor: University of Nebraska

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT04805320·Recruiting·Listed Mar 2021

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Effectiveness of Plaque Score Detection Techniques

for Plaque, Dental

1 location in Lincoln

Sponsor: University of Nebraska

Sex: All·Age: 19 - 85·Accepts healthy volunteers

Code: NCT06511830·Recruiting·Listed Jul 2024

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A Study of V132 in Healthy Older Participants (V132-001)

for Healthy

Sites in Lincoln, Omaha +7 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07712575·Phase 1·Recruiting·Listed Jul 2026

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An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

for High-risk Muscle Invasive Urothelial Carcinoma

Drug: Rilvegostomig

Sites in Lincoln, Omaha +16 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07720284·Phase 3·Recruiting·Listed Jul 2026

Apply to this trial

Cantharidin Application in Patients With Common Warts (Verruca Vulgaris) (COVE-3)

for Common Warts

Sites in Lincoln, Omaha +8 more locations

Sponsor: Verrica Pharmaceuticals Inc.

Sex: All·Age: 2+

Code: NCT07637734·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Single and Multiple Dose Study to Evaluate Safety and Pharmacokinetics of BMS-986533 in Healthy Participants and Assessments of Food and pH Effects on Relative Bioavailability, and Drug-Drug Interaction Potential in Healthy Participants

for Healthy Volunteers

1 location in Lincoln

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07629999·Phase 1·Recruiting·Listed Jun 2026

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Lincoln +47 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Lincoln +64 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

for Amyotrophic Lateral Sclerosis (ALS)

Sites in Lincoln +14 more locations

Sponsor: Zydus Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07023835·Phase 2·Recruiting·Listed Jun 2025

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

Sites in Lincoln +109 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting·Listed Mar 2024

Apply to this trial

A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee

for Osteoarthritis (OA) of the Knee

Sites in Lincoln +26 more locations

Sponsor: Pacira Pharmaceuticals, Inc

Sex: All·Age: 45 - 80

Code: NCT06884865·Phase 2·Recruiting·Listed Mar 2025

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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for Staphylococcus Aureus

Sites in Lincoln +39 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06749457·Phase 1, Phase 2·Recruiting·Listed Dec 2024

Apply to this trial

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Lincoln +60 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for Asthma

Sites in Lincoln, Omaha +94 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12 - 17

Code: NCT06307665·Phase 3·Recruiting·Listed Mar 2024

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for Carcinoma, Non-Small Cell Lung

Drug: Rilvegostomig

Sites in Lincoln +38 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06868277·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for Chickenpox

Sites in Lincoln +49 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06740630·Phase 3·Recruiting·Listed Dec 2024

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A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age

for Chickenpox

Sites in Lincoln +15 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06693895·Phase 3·Recruiting·Listed Nov 2024

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A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

for Excessive Daytime Sleepiness

Sites in Lincoln +2 more locations

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07082829·Phase 1·Recruiting·Listed Jul 2025

Apply to this trial