Clinical Trials at Children's Hospital Los Angeles

As of September 2026, 116 paid clinical trials are recruiting at Children's Hospital Los Angeles, located at 4650 W SUNSET BLVD, LOS ANGELES, CA 90027-6062, phone (323) 660-2450 in Los Angeles, California. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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119 clinical trials at Children's Hospital Los Angeles

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Los Angeles, Downey +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Los Angeles, Downey +200 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Los Angeles, Downey +141 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting·Listed May 2023

Apply to this trial

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

Sites in Los Angeles, Long Beach +100 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting·Listed May 2022

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Los Angeles, Palo Alto +20 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Los Angeles, Downey +78 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

for Children With Medical Complexity (CMC)

Sites in Los Angeles +1 more location

Sponsor: University of Utah

Sex: All·Age: 8+

Code: NCT07167927·Recruiting·Listed Sep 2025

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Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

for Recurrent World Health Organization (WHO) Grade II Glioma

Drug: Trametinib

Sites in Los Angeles, San Diego +13 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 25

Code: NCT04485559·Phase 1·Recruiting·Listed Jul 2020

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Losartan + Sunitinib in Treatment of Osteosarcoma

for Osteosarcoma

Sites in Los Angeles +3 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 10+

Code: NCT03900793·Phase 1·Recruiting·Listed Apr 2019

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Los Angeles, Downey +162 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

Apply to this trial

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

Sites in Los Angeles, Torrance +60 more locations

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Feasibility of the Reality PAWS Program for Children in Isolation

for Inpatient Pediatric Care

Sites in Los Angeles +1 more location

Sponsor: Children's Hospital Colorado

Sex: All·Age: 8 - 21

Code: NCT07187245·Recruiting·Listed Sep 2025

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Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

for B-cell Acute Lymphoblastic Leukemia

Sites in Los Angeles, Orange +14 more locations

Sponsor: Etan Orgel

Sex: All·Age: 7 - 25

Code: NCT05082519·Phase 2·Recruiting·Listed Oct 2021

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Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

for Congenital Central Hypoventilation Syndrome

Sites in Los Angeles +3 more locations

Sponsor: Ilya Khaytin

Sex: All·Age: 3 - 85

Code: NCT03568669·Recruiting·Listed Jun 2018

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Los Angeles, Orange +17 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB

for Short Bowel Syndrome

Sites in Los Angeles +1 more location

Sponsor: Boston Children's Hospital

Sex: All·Age: 2 - 18

Code: NCT03530852·Recruiting·Listed May 2018

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A Study to Give Treatment Inside the Eye to Treat Retinoblastoma

for Bilateral Retinoblastoma

Sites in Los Angeles, Palo Alto +14 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 18

Code: NCT05504291·Phase 2·Recruiting·Listed Aug 2022

Apply to this trial

Rett Syndrome Registry

for Rett Syndrome

Sites in Los Angeles, San Diego +17 more locations

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting·Listed Jun 2022

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Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

for Pediatric Cancer

Sites in Los Angeles +2 more locations

Sponsor: Nemours Children's Clinic

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05294302·Recruiting·Listed Mar 2022

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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

Drug: Irinotecan

Sites in Los Angeles, San Francisco +11 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting·Listed Jun 2024

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Los Angeles, San Diego +17 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

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Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth

for Social Anxiety Disorder

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 16 - 22·Accepts healthy volunteers

Code: NCT06526260·Recruiting·Listed Jul 2024

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Final Prototype Refinement of Adaptive Cell Phone Support

for Medication Adherence

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 15 - 20

Code: NCT07084155·Recruiting·Listed Jul 2025

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Childhood Cancer Survivor Study

for Cancer

Sites in Los Angeles, Duarte +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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International Rare Brain Tumor Registry

for Astroblastoma

Sites in Los Angeles, San Francisco +4 more locations

Sponsor: Children's National Research Institute

Sex: All·Age: Up to 45

Code: NCT05697874·Recruiting·Listed Jan 2023

Apply to this trial

Simulation Trial of Telemedical Support for Paramedics

for Emergencies

Sites in Los Angeles +7 more locations

Sponsor: Boston Medical Center

Sex: All·Age: 21+

Code: NCT06441760·Recruiting·Listed Jun 2024

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TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for Lymphoblastic Leukemia

Sites in Los Angeles, Orange +15 more locations

Sponsor: Tanja Andrea Gruber

Sex: All·Age: Up to 1

Code: NCT05848687·Phase 1, Phase 2·Recruiting·Listed May 2023

Apply to this trial

A Prospective Database of Infants With Cholestasis

for Biliary Atresia

Sites in Los Angeles +8 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: Up to 6 Months

Code: NCT00061828·Recruiting·Listed Jun 2003

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Improving Behavioral Health for Caregivers and Children After Pediatric Injury

for Quality of Life

Sites in Los Angeles +3 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06856057·Recruiting·Listed Mar 2025

Apply to this trial

Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth

for Sleep

Sites in Los Angeles +1 more location

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 12 - 18·Accepts healthy volunteers

Code: NCT07213908·Recruiting·Listed Oct 2025

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LIFE Cancer Survivorship Database for Pediatric Cancer

for Pediatric Cancer

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: All ages

Code: NCT01518400·Recruiting·Listed Jan 2012

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The Use of Butyrate Therapy in Pediatric Ulcerative Colitis

for Ulcerative Colitis

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 7 - 21

Code: NCT05218850·Phase 2·Recruiting·Listed Feb 2022

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DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

for Diabetes Mellitus Type 2, Childhood-Onset

Sites in Los Angeles +19 more locations

Sponsor: George Washington University

Sex: All·Age: 8 - 15

Code: NCT06525259·Recruiting·Listed Jul 2024

Apply to this trial

Retinoblastoma Patient Clinical Database and Tissue Repository

for Retinoblastoma

Sites in Los Angeles +7 more locations

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 0 - 18

Code: NCT04959097·Recruiting·Listed Jul 2021

Apply to this trial

Better Sleep Study

for Depression in Adolescence

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 12 - 18

Code: NCT06139861·Recruiting·Listed Nov 2023

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Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

for Race-related Stress

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 14 - 21

Code: NCT05685368·Phase 1, Phase 2·Recruiting·Listed Jan 2023

Apply to this trial

Bridge the Gap (BTG) - Black Youth Group

for Suicide Prevention

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 12 - 17·Accepts healthy volunteers

Code: NCT06880809·Recruiting·Listed Mar 2025

Apply to this trial

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

for HIE

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 1 Minute - 18·Accepts healthy volunteers

Code: NCT06195345·Recruiting·Listed Jan 2024

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CMV CTLs in Neonates With CMV Infection

for Congenital Cytomegaloviral (CMV) Disease

Sites in Los Angeles +3 more locations

Sponsor: New York Medical College

Sex: All·Age: 0 Days - 21 Days

Code: NCT05564598·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial