Paid Clinical Trials in Massachusetts

Massachusetts has 3,446 paid clinical trials enrolling now across cities including Boston, Worcester and Burlington. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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2,953 clinical trials

Clinical Course Of Disease In Participants With FA-CM

for Friedreich Ataxia

Sites in Boston +7 more locations

Sponsor: Lexeo Therapeutics

Sex: All·Age: 6+

Code: NCT06865482·Recruiting·Listed Mar 2025

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NEO100 and High-Grade Meningioma

for Residual, Progressive or Recurrent Grade II or III Meningioma

Sites in Boston +4 more locations

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 12+

Code: NCT05023018·Phase 2·Recruiting·Listed Aug 2021

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Randomized Trial of UI-EWD vs. Conventional Endoscopic Therapy for Nonvariceal Upper Gastrointestinal Bleeding

for Acute Gastrointestinal Bleeding

Sites in Boston +5 more locations

Sponsor: Medtronic - MITG

Sex: All·Age: 22+

Code: NCT06188585·Recruiting·Listed Jan 2024

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ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

for Advanced Solid Tumor

Sites in Boston +4 more locations

Sponsor: Adcendo ApS

Sex: All·Age: 18+

Code: NCT06597721·Phase 1·Recruiting·Listed Sep 2024

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Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area

for Anastomotic Leaks

Sites in Burlington +8 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07035431·Recruiting·Listed Jun 2025

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FIBERGRAFT Aeridyan Posterolateral Fusion Study

for Degenerative Spine Disease

Sites in Boston +7 more locations

Sponsor: DePuy Synthes Products, Inc.

Sex: All·Age: 18+

Code: NCT07059065·Recruiting·Listed Jul 2025

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LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

Sites in Boston +2 more locations

Sponsor: OrphAI Therapeutics

Sex: All·Age: 18 - 80

Code: NCT05798923·Phase 2·Recruiting·Listed Apr 2023

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A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

for Small Cell Lung Cancer

Drug: Gocatamig

Sites in Boston +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06780137·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

for Coronary Artery Disease

Sites in Boston +9 more locations

Sponsor: Teleflex

Sex: All·Age: 18+

Code: NCT06779630·Recruiting·Listed Jan 2025

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A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

for Pancreatic Ductal Adenocarcinoma

Sites in Boston +2 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07024615·Phase 1·Recruiting·Listed Jun 2025

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Radiation Free Study

for Aortic Aneurysm

Sites in Boston, Worcester +3 more locations

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT06549348·Recruiting·Listed Aug 2024

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Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for Small Cell Lung Carcinoma

Sites in Boston +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07006727·Phase 1·Recruiting·Listed Jun 2025

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An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease

for Vanishing White Matter Disease

Sites in Boston +2 more locations

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 6 Months+

Code: NCT05757141·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

for Hypertension

1 location in Boston

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT07174622·Recruiting·Listed Sep 2025

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Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

for Myeloid Leukemia, Philadelphia Positive

Sites in Boston +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 1 - 17

Code: NCT04925479·Phase 1, Phase 2·Recruiting·Listed Jun 2021

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KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

for Mitochondrial Diseases

Sites in Boston +2 more locations

Sponsor: Khondrion BV

Sex: All·Age: 18+

Code: NCT06451757·Phase 3·Recruiting·Listed Jun 2024

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A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

for Head and Neck Squamous Cell Carcinoma HNSCC

Sites in Boston +5 more locations

Sponsor: Sutro Biopharma, Inc.

Sex: All·Age: 18+

Code: NCT07227168·Phase 1·Recruiting·Listed Nov 2025

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Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

for Adenoid Cystic Carcinoma

Sites in Boston +6 more locations

Sponsor: Remix Therapeutics

Sex: All·Age: 18+

Code: NCT06118086·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)

for Relapsed/Refractory Systemic Light Chain Amyloidosis

Drug: Linvoseltamab

Sites in Boston +7 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06292780·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

for Renal Cell Carcinoma

Sites in Boston +5 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06966024·Phase 1·Recruiting·Listed May 2025

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Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

for Congenital Heart Disease

Sites in Boston +7 more locations

Sponsor: Starlight Cardiovascular Inc

Sex: All·Age: 1 Minute - 6 Months

Code: NCT07114718·Recruiting·Listed Aug 2025

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A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

for SLE (Systemic Lupus)

Sites in Boston +6 more locations

Sponsor: CRISPR Therapeutics

Sex: All·Age: 18 - 70

Code: NCT06925542·Phase 1·Recruiting·Listed Apr 2025

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A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

for Moderate to Severe Plaque Psoriasis

Drug: Bimekizumab

Sites in Boston +5 more locations

Sponsor: UCB Biopharma SRL

Sex: Female·Age: 18+

Code: NCT06888193·Phase 1·Recruiting·Listed Mar 2025

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Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for Pancreatic Ductal Adenocarcinoma

Sites in Boston +8 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06562192·Phase 1·Recruiting·Listed Aug 2024

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Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

for Locally Advanced Cholangiocarcinoma

Sites in Boston +3 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06160752·Phase 1·Recruiting·Listed Dec 2023

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A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease.

for Chagas Disease

Sites in Boston +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 60

Code: NCT06632600·Phase 2·Recruiting·Listed Oct 2024

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Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

for Agitation

Sites in Worcester +5 more locations

Sponsor: Teikoku Pharma USA, Inc.

Sex: All·Age: All ages

Code: NCT06052254·Phase 2·Recruiting·Listed Sep 2023

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A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

for Congenital Myasthenic Syndrome

Sites in Boston +5 more locations

Sponsor: argenx

Sex: All·Age: 2+

Code: NCT06078553·Recruiting·Listed Oct 2023

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Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

for Arthritis

Sites in Boston +5 more locations

Sponsor: Aptis Medical

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05796908·Recruiting·Listed Apr 2023

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A Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk

for Relapsing Multiple Sclerosis

Sites in Boston +4 more locations

Sponsor: TG Therapeutics, Inc.

Sex: Female·Age: 18+

Code: NCT06143514·Recruiting·Listed Nov 2023

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A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

for Metastatic Solid Tumors

Sites in Boston +6 more locations

Sponsor: Erasca, Inc.

Sex: All·Age: 18 - 99

Code: NCT06983743·Phase 1·Recruiting·Listed May 2025

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Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

for HER2-Positive Solid Tumor

Sites in Boston +1 more location

Sponsor: Yuhan Corporation

Sex: All·Age: 18+

Code: NCT05523947·Phase 1, Phase 2·Recruiting·Listed Sep 2022

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Anti-GD2 ADC M3554 in Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Boston +1 more location

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18+

Code: NCT06641908·Phase 1·Recruiting·Listed Oct 2024

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Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

for Vitamin K-Dependent Coagulation Defect

1 location in Boston

Sponsor: Octapharma

Sex: All·Age: 18+

Code: NCT06429787·Recruiting·Listed May 2024

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Long-term Follow-up of Participants Treated With Galapagos Chimeric Antigen Receptor (CAR) T-cell Therapies

for Hematological Malignancies

1 location in Boston

Sponsor: Lakefront Biotherapeutics NV

Sex: All·Age: 18+

Code: NCT06652633·Phase 3·Recruiting·Listed Oct 2024

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A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Sites in Boston +8 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07111520·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

for Advanced Solid Tumor

Sites in Boston +4 more locations

Sponsor: Senhwa Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04890613·Phase 1·Recruiting·Listed May 2021

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A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

for Myotonic Dystrophy Type 1 (DM1)

Sites in Boston +7 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 64

Code: NCT06185764·Phase 1, Phase 2·Recruiting·Listed Dec 2023

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The Mycophenolate Pregnancy Registry

for Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases

1 location in Cambridge

Sponsor: Genentech, Inc.

Sex: Female·Age: All ages

Code: NCT01733082·Recruiting·Listed Nov 2012

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A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for Monoclonal Gammopathy of Undetermined Significance (MGUS)

Drug: Linvoseltamab

Sites in Boston +6 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06140524·Phase 2·Recruiting·Listed Nov 2023

Apply to this trial