Paid Clinical Trials in Massachusetts

Massachusetts has 3,446 paid clinical trials enrolling now across cities including Boston, Worcester and Burlington. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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2,953 clinical trials

At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.

for Stroke

1 location in Charlestown

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 80

Code: NCT06787729·Recruiting·Listed Jan 2025

Apply to this trial

Nutrition for Precision Health, Powered by the All of Us

for Nutrition

Sites in Boston +13 more locations

Sponsor: RTI International

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05701657·Recruiting·Listed Jan 2023

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

Sites in Boston +9 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting·Listed Oct 2021

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Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment

for CPPD - Calcium Pyrophosphate Deposition Disease

Sites in Boston +4 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40+

Code: NCT06855433·Phase 2·Recruiting·Listed Mar 2025

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SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

for Epithelioid Hemangioendothelioma (EHE)

Sites in Boston +5 more locations

Sponsor: Sarcoma Alliance for Research through Collaboration

Sex: All·Age: 18+

Code: NCT07104331·Phase 2·Recruiting·Listed Aug 2025

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Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)

for PSC

Sites in Boston +10 more locations

Sponsor: PSC Partners Seeking a Cure

Sex: All·Age: 18 - 75

Code: NCT06297993·Recruiting·Listed Mar 2024

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Evaluation of A Clinical Diagnostic Test for CRDS

for Calcium Release Deficiency Syndrome (CRDS)

Sites in Boston +3 more locations

Sponsor: Population Health Research Institute

Sex: All·Age: All ages

Code: NCT06188689·Recruiting·Listed Jan 2024

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Boston +39 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Striae Distensae Treatment Using Deep Skin Abrasion

for Striae Distensae

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 70

Code: NCT07087405·Recruiting·Listed Jul 2025

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Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

for Developmental and Epileptic Encephalopathies

1 location in Boston

Sponsor: Heather Olson

Sex: All·Age: 0 Days - 9 Months

Code: NCT06700811·Phase 1·Recruiting·Listed Nov 2024

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A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB

for Short Bowel Syndrome

Sites in Boston +1 more location

Sponsor: Boston Children's Hospital

Sex: All·Age: 2 - 18

Code: NCT03530852·Recruiting·Listed May 2018

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Study of an Oral Fluid Testing Approach

for Cannabis Use

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 30

Code: NCT06891235·Recruiting·Listed Mar 2025

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Boston, Worcester +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Specimens

for Infertility

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 18+

Code: NCT07074015·Recruiting·Listed Jul 2025

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Circulating Tumor DNA

for ER+ Breast Cancer

Sites in Boston +6 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06923527·Phase 2·Recruiting·Listed Apr 2025

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Boston +44 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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Genetic and Environmental Risk Factors for Hemorrhagic Stroke

for Stroke

Sites in Boston +6 more locations

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00682695·Recruiting·Listed May 2008

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Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

Sites in Boston, Worcester +16 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting·Listed Dec 2024

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Simulation Trial of Telemedical Support for Paramedics

for Emergencies

Sites in Boston +7 more locations

Sponsor: Boston Medical Center

Sex: All·Age: 21+

Code: NCT06441760·Recruiting·Listed Jun 2024

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Boston +70 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for High Grade Glioma

Sites in Boston +9 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 21·Accepts healthy volunteers

Code: NCT06333899·EARLY_Phase 1·Recruiting·Listed Mar 2024

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Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants

for Bronchopulmonary Dysplasia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Hours - 1

Code: NCT05777512·Recruiting·Listed Mar 2023

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A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome

for Memory Replay

1 location in Chestnut Hill

Sponsor: Boston College

Sex: All·Age: 15 - 35

Code: NCT07008989·Recruiting·Listed Jun 2025

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Boston, Worcester +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Boston, Ayer +45 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk

for Overdose

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 13+

Code: NCT07022717·Recruiting·Listed Jun 2025

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Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis

for Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring

Sites in Boston +11 more locations

Sponsor: University of Southern California

Sex: All·Age: 60+

Code: NCT06496867·Recruiting·Listed Jul 2024

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Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care

for Hiv

Sites in Boston +2 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05241990·Recruiting·Listed Feb 2022

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Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for Inherited Retinal Degeneration

Sites in Boston +18 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4+

Code: NCT05589714·Recruiting·Listed Oct 2022

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Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

for Prediabetes

1 location in Sommerville

Sponsor: Cambridge Health Alliance

Sex: All·Age: 18 - 60

Code: NCT06988462·Recruiting·Listed May 2025

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Imagined Acupuncture for Postoperative Pain After Spinal Surgery

for Pain Management

1 location in Boston

Sponsor: Jingping Wang, MD, Ph.D.

Sex: All·Age: 18+

Code: NCT07197710·Recruiting·Listed Sep 2025

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

Sites in Boston +22 more locations

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting·Listed Jan 2023

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Biomarkers to Enhance Early Schizophrenia Treatment

for Schizophenia Disorder

Sites in Belmont +3 more locations

Sponsor: Northwell Health

Sex: All·Age: 18 - 35

Code: NCT06969755·Phase 4·Recruiting·Listed May 2025

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Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy

for Prostate Cancer

1 location in Boston

Sponsor: Shehzad Basaria, M.D.

Sex: Male·Age: 40+

Code: NCT06957691·Phase 2·Recruiting·Listed May 2025

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Tolerance Through Mixed Chimerism (Sip-Tego)

for Kidney Failure

1 location in Boston

Sponsor: Tatsuo Kawai, MD, PhD

Sex: All·Age: 18 - 65

Code: NCT06972069·EARLY_Phase 1·Recruiting·Listed May 2025

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in Boston +26 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

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RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer

for Endometrial Cancer

3 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT03675893·Phase 2·Recruiting·Listed Sep 2018

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

Sites in Boston +8 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting·Listed Sep 2019

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Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

for Recurrent Chronic Lymphocytic Leukemia

Drug: Mirdametinib

Sites in Boston +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061951·Phase 2·Recruiting·Listed Jul 2025

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in Boston +29 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial