Oncology Clinical Trials in Memphis, TN

As of July 2026, 109 paid clinical trials are recruiting for Oncology in Memphis, Tennessee. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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110 clinical trials for Oncology

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Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

for Refractory Solid Tumor

Drug: Atezolizumab

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT05468359·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for High Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 3

Code: NCT06528691·Phase 2·Recruiting·Listed Jul 2024

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Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

for Solid Tumor

Sites in Memphis +2 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 20

Code: NCT05645523·EARLY_Phase 1·Recruiting·Listed Dec 2022

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Memphis, Nashville +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Indocyanine Green (ICG) Guided Tumor Resection

for Neoplastic Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04084067·Phase 1·Recruiting·Listed Sep 2019

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Childhood Cancer Survivors' Affective Response to Exercise

for ALL, Childhood

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 39

Code: NCT05763290·Recruiting·Listed Mar 2023

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Memphis +82 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Memphis, Nashville +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

for Differentiated Thyroid Cancer

Sites in Memphis +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 25

Code: NCT06458036·Phase 2·Recruiting·Listed Jun 2024

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Neuroblastoma Biology Study

for Neuroblastoma

Sites in Memphis +13 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

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CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia

for Acute Lymphoblastic Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT06847269·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

Sites in Memphis +15 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting·Listed Jan 2024

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A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

for Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 25

Code: NCT06810583·Phase 1·Recruiting·Listed Feb 2025

Apply to this trial

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

for Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT06326463·Phase 1·Recruiting·Listed Mar 2024

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Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

Sites in Memphis +7 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting·Listed Aug 2021

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Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

Sites in Memphis +4 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting·Listed Mar 2023

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Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

for Melanoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT02775643·Recruiting·Listed May 2016

Apply to this trial

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Memphis +21 more locations

Sponsor: National Cancer Institute LAO

Sex: All·Age: 2 Months+

Code: NCT02474160·Recruiting·Listed Jun 2015

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

Sites in Memphis +5 more locations

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting·Listed Aug 2020

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Making Healthy Habits Stick

for Cancer

Sites in Memphis +1 more location

Sponsor: University of Tennessee

Sex: Female·Age: 19+

Code: NCT06745180·Recruiting·Listed Dec 2024

Apply to this trial

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Memphis, Nashville +15 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

Sites in Memphis +2 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting·Listed Jan 2022

Apply to this trial

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Memphis +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Memphis +47 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Newly Diagnosed, Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

for Desmoplastic Small Round Cell Tumor

Sites in Memphis +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 39

Code: NCT04616560·Phase 1, Phase 2·Recruiting·Listed Nov 2020

Apply to this trial

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

for Cancer

Sites in Memphis +5 more locations

Sponsor: Helio Genomics

Sex: All·Age: 18+

Code: NCT05181826·Recruiting·Listed Jan 2022

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A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Memphis, Nashville +59 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06496178·Phase 3·Recruiting·Listed Jul 2024

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Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Memphis, Nashville +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 95

Code: NCT05061550·Phase 2·Recruiting·Listed Sep 2021

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Memphis, Nashville +34 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

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Conditions in Oncology (Memphis, TN)

Non-small cell lung cancer (NSCLC)· 20 Acute myeloid leukemia (AML)· 13 Cancer (any)· 12 Hematologic malignancy· 11 Solid tumor· 11 Breast cancer· 8 Leukemia (other)· 8 Non-Hodgkin lymphoma· 8 Neuroblastoma· 8 Acute lymphoblastic leukemia· 7 Colorectal cancer· 6 Myelodysplastic syndromes (MDS)· 6 Hodgkin lymphoma· 6 Pediatric cancer· 6 Melanoma· 5 Head and neck cancer· 5 Osteosarcoma· 4 Ewing sarcoma· 4 Rhabdomyosarcoma· 4 Pancreatic cancer· 3 Esophageal cancer· 3 Prostate cancer· 3 Ovarian cancer· 3 Multiple myeloma· 3 Metastatic breast cancer· 2 Lung cancer· 2 Bladder cancer· 2 Endometrial cancer· 2 Glioma· 2 Brain cancer· 2 Chronic lymphocytic leukemia (CLL)· 2 Myeloproliferative neoplasm· 2 Sarcoma· 2 Soft tissue sarcoma· 2 Small cell lung cancer· 1 Gastric cancer· 1 Gastroesophageal junction cancer· 1 Liver cancer· 1 Biliary tract cancer· 1 Metastatic prostate cancer· 1 Cervical cancer· 1 Uterine cancer· 1 Glioblastoma· 1 Myelofibrosis· 1 Diffuse large B-cell lymphoma (DLBCL)· 1 Follicular lymphoma· 1 Mantle cell lymphoma· 1 Marginal zone lymphoma· 1 Small lymphocytic lymphoma· 1 Thyroid cancer· 1 Neuroendocrine tumors· 1