Oncology Clinical Trials in Minneapolis, MN

As of July 2026, 163 paid clinical trials are recruiting for Oncology in Minneapolis, Minnesota. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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165 clinical trials for Oncology

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Minneapolis, Saint Louis Park +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

Apply to this trial

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

for Hodgkin Lymphoma

Drug: Ruxolitinib

Sites in Minneapolis +2 more locations

Sponsor: Veronika Bachanova

Sex: All·Age: 18+

Code: NCT03681561·Phase 1, Phase 2·Recruiting·Listed Sep 2018

Apply to this trial

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Epcoritamab

Sites in Minneapolis +1 more location

Sponsor: Yazeed Sawalha

Sex: All·Age: 18+

Code: NCT06536049·Phase 1, Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Minneapolis +179 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

for Ovarian Cancer

Sites in Minneapolis +9 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 50 - 74·Accepts healthy volunteers

Code: NCT00539162·Recruiting·Listed Oct 2007

Apply to this trial

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Minneapolis +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

Apply to this trial

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Minneapolis, Rochester +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

Apply to this trial

An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

Sites in Minneapolis, Saint Louis Park +147 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting·Listed Jul 2020

Apply to this trial

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Minneapolis +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

Apply to this trial

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

Sites in Minneapolis, Saint Louis Park +140 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting·Listed Jun 2019

Apply to this trial

Backtracking Leukemia-Typical Somatic Mutations in Cord Blood

for Acute Lymphoblastic Leukemia

1 location in Minneapolis

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT05014165·Recruiting·Listed Aug 2021

Apply to this trial

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

for Hematologic Malignancy

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 60

Code: NCT05735717·Phase 2·Recruiting·Listed Feb 2023

Apply to this trial

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

Sites in Minneapolis, Saint Louis Park +42 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting·Listed Aug 2021

Apply to this trial

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Minneapolis, Saint Louis Park +301 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

Apply to this trial

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

Sites in Minneapolis, Saint Louis Park +338 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020

Apply to this trial

Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

Sites in Minneapolis +16 more locations

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting·Listed Jan 2021

Apply to this trial

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

for Fanconi Anemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 65

Code: NCT03579875·Phase 2·Recruiting·Listed Jul 2018

Apply to this trial

LEgal Guidance and AdvocaCY for CAREgivers (LEGACY CARE): A Pilot Clinical Trial for Caregivers of Persons With Colorectal Cancer

for Caregiver Burden

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07153016·Recruiting·Listed Sep 2025

Apply to this trial

National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

Sites in Minneapolis +17 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting·Listed Oct 2023

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Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy

for Hematopoietic and Lymphatic System Neoplasm

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06414278·Recruiting·Listed May 2024

Apply to this trial

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Minneapolis +125 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

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Study of PAT in Patients With Solid Tumor Cancers

for Metastasis

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT05338658·Phase 1·Recruiting·Listed Apr 2022

Apply to this trial

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

for Chronic Lung Disease

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 8 - 25

Code: NCT05025774·Recruiting·Listed Aug 2021

Apply to this trial

Auto Stem Cell Transplant for Lymphoma Patients

for Non-Hodgkin Lymphoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 75

Code: NCT03125642·Phase 2·Recruiting·Listed Apr 2017

Apply to this trial

Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer

for Prostate Cancer

Sites in Minneapolis, Rochester +3 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male·Age: 18+

Code: NCT06014255·Phase 2·Recruiting·Listed Aug 2023

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Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

for Neuroblastoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 30

Code: NCT02605421·Phase 2·Recruiting·Listed Nov 2015

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Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT07008638·Phase 1, Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

for Adenocarcinoma of Lung

Drug: Durvalumab

Sites in Minneapolis, Brainerd +8 more locations

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT04105270·Phase 2·Recruiting·Listed Sep 2019

Apply to this trial

HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

for Follicular Lymphoma

Drug: Tafasitamab

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06792825·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

CIBMTR Research Database

for Autologous Stem Cell Transplantation

Sites in Minneapolis +1 more location

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01166009·Recruiting·Listed Jul 2010

Apply to this trial

PRE-I-SPY Phase I/Ib Oncology Platform Program

for HER2-positive Breast Cancer

Sites in Minneapolis +6 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT05868226·Phase 1·Recruiting·Listed May 2023

Apply to this trial

International PPB/DICER1 Registry

for Pleuropulmonary Blastoma

1 location in Minneapolis

Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: All·Age: 0 Minutes - 100·Accepts healthy volunteers

Code: NCT03382158·Recruiting·Listed Dec 2017

Apply to this trial

Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis

for Myelofibrosis

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 55+

Code: NCT02934477·Recruiting·Listed Oct 2016

Apply to this trial

Assessment of Allogeneic Hematopoietic Cell Transplantation in Medicare Beneficiaries With Multiple Myeloma

for Multiple Myeloma

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT03127761·Recruiting·Listed Apr 2017

Apply to this trial

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Minneapolis +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

Apply to this trial

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Minneapolis +9 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Recruiting·Listed May 2026

Apply to this trial

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

Sites in Minneapolis +65 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

Sites in Minneapolis, Rochester +43 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting·Listed May 2025

Apply to this trial

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

for Cancer

Sites in Minneapolis, Fridley +4 more locations

Sponsor: Helio Genomics

Sex: All·Age: 18+

Code: NCT05181826·Recruiting·Listed Jan 2022

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A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

for Solid Tumors

Sites in Minneapolis +16 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06431594·Phase 1·Recruiting·Listed May 2024

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Conditions in Oncology (Minneapolis, MN)

Solid tumor· 23 Non-small cell lung cancer (NSCLC)· 20 Acute myeloid leukemia (AML)· 18 Breast cancer· 16 Ovarian cancer· 16 Cancer (any)· 13 Endometrial cancer· 11 Colorectal cancer· 10 Hematologic malignancy· 9 Metastatic breast cancer· 8 Myelodysplastic syndromes (MDS)· 8 Melanoma· 8 Prostate cancer· 7 Leukemia (other)· 7 Non-Hodgkin lymphoma· 7 Neuroblastoma· 7 Metastatic prostate cancer· 6 Multiple myeloma· 6 Chronic lymphocytic leukemia (CLL)· 6 Acute lymphoblastic leukemia· 6 Head and neck cancer· 6 Small lymphocytic lymphoma· 5 Pancreatic cancer· 4 Cervical cancer· 4 Fallopian tube cancer· 4 Myelofibrosis· 4 Hodgkin lymphoma· 4 Follicular lymphoma· 4 Triple-negative breast cancer· 3 HER2-negative breast cancer· 3 Esophageal cancer· 3 Kidney cancer· 3 Glioblastoma· 3 HER2-positive breast cancer· 2 Lung cancer· 2 Gastroesophageal junction cancer· 2 Liver cancer· 2 Bladder cancer· 2 Brain cancer· 2 Myeloproliferative neoplasm· 2 Diffuse large B-cell lymphoma (DLBCL)· 2 Marginal zone lymphoma· 2 Burkitt lymphoma· 2 Thyroid cancer· 2 Sarcoma· 2 Gastric cancer· 1 Glioma· 1 Brain metastases· 1 Mantle cell lymphoma· 1 Osteosarcoma· 1 Ewing sarcoma· 1 Rhabdomyosarcoma· 1 Pediatric cancer· 1 Mesothelioma· 1