Oncology Clinical Trials in Minneapolis, MN

As of August 2026, 159 paid clinical trials are recruiting for Oncology in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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160 clinical trials for Oncology

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Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

Sites in Minneapolis +2 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543·Recruiting·Listed Jan 2025

Apply to this trial

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Minneapolis, Saint Louis Park +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

Sites in Minneapolis +19 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Allo HSCT Using RIC and PTCy for Hematological Diseases

for Acute Myelogenous Leukemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 75

Code: NCT05805605·Phase 2·Recruiting·Listed Apr 2023

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Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

for Multiple Myeloma

Drug: Talquetamab

Sites in Minneapolis +15 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT05972135·Phase 2·Recruiting·Listed Aug 2023

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Minneapolis, Saint Louis Park +31 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

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Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

for Acute Leukemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 60

Code: NCT03314974·Phase 2·Recruiting·Listed Oct 2017

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Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

for Hodgkin Lymphoma

Drug: Ruxolitinib

Sites in Minneapolis +2 more locations

Sponsor: Veronika Bachanova

Sex: All·Age: 18+

Code: NCT03681561·Phase 1, Phase 2·Recruiting·Listed Sep 2018

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Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

for Neuroblastoma

Sites in Minneapolis +19 more locations

Sponsor: Giselle Sholler

Sex: All·Age: Up to 22

Code: NCT02559778·Phase 2·Recruiting·Listed Sep 2015

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Minneapolis, Saint Louis Park +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

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Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

for Ovarian Cancer

Sites in Minneapolis +9 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 50 - 74·Accepts healthy volunteers

Code: NCT00539162·Recruiting·Listed Oct 2007

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Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

Sites in Minneapolis, Saint Louis Park +140 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting·Listed Jun 2019

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Minneapolis +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Minneapolis, Saint Louis Park +301 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

Sites in Minneapolis, Saint Louis Park +338 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020

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Backtracking Leukemia-Typical Somatic Mutations in Cord Blood

for Acute Lymphoblastic Leukemia

1 location in Minneapolis

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT05014165·Recruiting·Listed Aug 2021

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MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

for Hematologic Malignancy

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 60

Code: NCT05735717·Phase 2·Recruiting·Listed Feb 2023

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Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

Sites in Minneapolis, Saint Louis Park +42 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting·Listed Aug 2021

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Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

Sites in Minneapolis +16 more locations

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting·Listed Jan 2021

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Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

for Fanconi Anemia

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 65

Code: NCT03579875·Phase 2·Recruiting·Listed Jul 2018

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Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy

for Hematopoietic and Lymphatic System Neoplasm

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06414278·Recruiting·Listed May 2024

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LEgal Guidance and AdvocaCY for CAREgivers (LEGACY CARE): A Pilot Clinical Trial for Caregivers of Persons With Colorectal Cancer

for Caregiver Burden

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07153016·Recruiting·Listed Sep 2025

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Study of PAT in Patients With Solid Tumor Cancers

for Metastasis

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT05338658·Phase 1·Recruiting·Listed Apr 2022

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Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

for Chronic Lung Disease

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 8 - 25

Code: NCT05025774·Recruiting·Listed Aug 2021

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Auto Stem Cell Transplant for Lymphoma Patients

for Non-Hodgkin Lymphoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 75

Code: NCT03125642·Phase 2·Recruiting·Listed Apr 2017

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Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

for Neuroblastoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 30

Code: NCT02605421·Phase 2·Recruiting·Listed Nov 2015

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RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

for Adenocarcinoma of Lung

Drug: Durvalumab

Sites in Minneapolis, Brainerd +8 more locations

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT04105270·Phase 2·Recruiting·Listed Sep 2019

Apply to this trial

CIBMTR Research Database

for Autologous Stem Cell Transplantation

Sites in Minneapolis +1 more location

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01166009·Recruiting·Listed Jul 2010

Apply to this trial

PRE-I-SPY Phase I/Ib Oncology Platform Program

for HER2-positive Breast Cancer

Sites in Minneapolis +6 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT05868226·Phase 1·Recruiting·Listed May 2023

Apply to this trial

International PPB/DICER1 Registry

for Pleuropulmonary Blastoma

1 location in Minneapolis

Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: All·Age: 0 Minutes - 100·Accepts healthy volunteers

Code: NCT03382158·Recruiting·Listed Dec 2017

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Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis

for Myelofibrosis

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 55+

Code: NCT02934477·Recruiting·Listed Oct 2016

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Assessment of Allogeneic Hematopoietic Cell Transplantation in Medicare Beneficiaries With Multiple Myeloma

for Multiple Myeloma

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT03127761·Recruiting·Listed Apr 2017

Apply to this trial

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Minneapolis +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

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Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Minneapolis +10 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Recruiting·Listed May 2026

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A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

for HNSCC

Sites in Minneapolis +17 more locations

Sponsor: Normunity AccelCo, Inc.

Sex: All·Age: 18+

Code: NCT07182149·Phase 1·Recruiting·Listed Sep 2025

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

Sites in Minneapolis, Rochester +46 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting·Listed May 2025

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Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

Sites in Minneapolis +66 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025

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A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

for Solid Tumors

Sites in Minneapolis +16 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06431594·Phase 1·Recruiting·Listed May 2024

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Minneapolis +35 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

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Conditions in Oncology (Minneapolis, MN)

Solid tumor· 24 Non-small cell lung cancer (NSCLC)· 20 Acute myeloid leukemia (AML)· 18 Breast cancer· 17 Ovarian cancer· 17 Cancer (any)· 13 Colorectal cancer· 11 Endometrial cancer· 11 Hematologic malignancy· 9 Metastatic breast cancer· 8 Multiple myeloma· 8 Myelodysplastic syndromes (MDS)· 8 Melanoma· 8 Leukemia (other)· 7 Non-Hodgkin lymphoma· 7 Neuroblastoma· 7 Prostate cancer· 6 Metastatic prostate cancer· 6 Acute lymphoblastic leukemia· 6 Head and neck cancer· 6 Chronic lymphocytic leukemia (CLL)· 5 Lung cancer· 4 Pancreatic cancer· 4 Cervical cancer· 4 Fallopian tube cancer· 4 Myelofibrosis· 4 Hodgkin lymphoma· 4 Small lymphocytic lymphoma· 4 Triple-negative breast cancer· 3 HER2-negative breast cancer· 3 Esophageal cancer· 3 Kidney cancer· 3 Follicular lymphoma· 3 HER2-positive breast cancer· 2 Gastroesophageal junction cancer· 2 Liver cancer· 2 Bladder cancer· 2 Glioblastoma· 2 Brain cancer· 2 Myeloproliferative neoplasm· 2 Diffuse large B-cell lymphoma (DLBCL)· 2 Marginal zone lymphoma· 2 Burkitt lymphoma· 2 Thyroid cancer· 2 Sarcoma· 2 Gastric cancer· 1 Brain metastases· 1 Mantle cell lymphoma· 1 Osteosarcoma· 1 Ewing sarcoma· 1 Rhabdomyosarcoma· 1 Pediatric cancer· 1 Mesothelioma· 1