Paid Clinical Trials in Minneapolis, MN
As of July 2026, 906 paid clinical trials are recruiting in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Minneapolis offers studies at sites including University of Minnesota for conditions such as Acute Myeloid Leukemia, Heart Failure, Ovarian Cancer, Parkinson Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Minneapolis
Trials by drug in Minneapolis
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Newly added in Minneapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Capturing Food Intake in Patients Undergoing Radiation Therapy for Cancer
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
Feasibility of a Remotely Delivered Step Count Intervention in Chronic Stroke
MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients
822 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Top Research Study Locations in Minneapolis
Researchers run research studies in Minneapolis, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Minnesota | Parkinson Disease, Depression, REM Sleep Behavior Disorder | 305 |
| Abbott-Northwestern Hospital | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8 | 84 |
| Hennepin County Medical Center | Malignant Solid Neoplasm, Stage IV Renal Cell Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | 72 |
| University of Minnesota/Masonic Cancer Center | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm | 39 |
| Minneapolis Heart Institute Foundation | Coronary Artery Disease, Cardiovascular Diseases, Heart Failure | 30 |
| Minneapolis VA Health Care System, Minneapolis, MN | Amputation, Bipolar Disorder, Spinal Cord Diseases | 28 |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 26 |
| Health Partners Inc | Stage IVB Prostate Cancer AJCC v8, Malignant Solid Neoplasm, Ovarian Carcinoma | 26 |
| Masonic Cancer Center | Acute Myeloid Leukemia, Smoking Cessation, Acute Lymphoblastic Leukemia | 15 |
| University of Minnesota Medical Center | ADA SCID, Advanced Melanoma, Aortic Stenosis | 15 |
| Minneapolis Heart Institute | Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases | 13 |
| Minneapolis VA Medical Center | Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 | 13 |
| Abbott Northwestern Hospital | AMI, Acute Stroke, Aneurysm Cerebral | 11 |
| M Health Fairview University of Minnesota Medical Center | Ischemic Stroke, Prostate Cancer, Adamantinomatous Craniopharyngioma | 9 |
| Minneapolis VA Health Care System | Heart Failure, Aging Related Cognitive Decline, Chronic Obstructive Pulmonary Disease | 8 |
| University of Minnesota Masonic Children's Hospital | Fabry Disease, High-Risk Neuroblastoma, Hypochondroplasia | 8 |
| University of Minnesota Medical School | Niemann-Pick Type C Disease, Advanced Solid Tumor, Alopecia | 8 |
| Allina Health Cancer Institute - Abbott Northwestern Hospital | Neoplasm Metastasis, Advanced Hepatocellular Carcinoma, Breast Cancer | 8 |
| Children's Hospitals and Clinics of Minnesota | Cystic Fibrosis, B-cell Acute Lymphoblastic Leukemia, Caregiver Burden | 8 |
| Children's Minnesota | ALK Fusion-positive Solid or CNS Tumors, Ciliary Body Medulloepithelioma, Craniopharyngioma | 7 |
| Masonic Cancer Center at University of Minnesota | Myelodysplastic Syndromes, Acute Leukemia, Acute Myeloid Leukemia | 7 |
| Masonic Cancer Center, University of Minnesota | Adenocarcinoma of Lung, Alcohol-Related Carcinoma, Epithelial Ovarian Cancer | 7 |
| Children's Hospital and Clinics of Minnesota | Neuroblastoma, ALL, AML | 6 |
| Hennepin Healthcare | Acute Respiratory Failure, Awareness, Carcinoma, Hepatocellular | 6 |
| Hennepin Healthcare Research Institute | Acute Compartment Syndrome, Aging, Atrial Fibrillation | 5 |
Active & Upcoming Studies in Minneapolis (2026)
Recruiting trials in Minneapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (248 active studies)
- Signatera Assessment in Early-Stage Endometrial Cancer · Natera, Inc.
- ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening · VA Office of Research and Development
Cardiovascular (67 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients · University of Minnesota
Neurology & pain (55 active studies)
- Simultaneous Engagement of Networks for Alleviating Pain (SENAP) · Phase 1 · University of Minnesota
- Myofunctional Therapy for Obstructive Sleep Apnea · University of Minnesota
Diabetes & metabolic (42 active studies)
- GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward · Phase 4 · University of Minnesota
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Mental health & behavior (30 active studies)
- ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening · VA Office of Research and Development
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
Pediatric (14 active studies)
- Magnesium Sulfate in Pediatric Burn Dressing Changes · Phase 1 · Hennepin Healthcare Research Institute
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
HIV / STI (7 active studies)
- Combating HIV Stigma in Healthcare Settings: A Standardized Patient Approach · University of Minnesota
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
Eye & vision (5 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma · Phase 3 · AbbVie
Vaccines (3 active studies)
- H1ssF Flu Vaccine Clinical Trial · Phase 1 · University of Minnesota
- Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID · Phase 3 · Wes Ely
Common conditions studied in Minneapolis
- Acute Myeloid Leukemia (16 active studies)
- Heart Failure (16 active studies)
- Ovarian Cancer (13 active studies)
- Parkinson Disease (12 active studies)
- Breast Cancer (11 active studies)
- Endometrial Cancer (11 active studies)
Leading research sponsors in Minneapolis
- University of Minnesota
- National Cancer Institute (NCI)
- Masonic Cancer Center, University of Minnesota
- VA Office of Research and Development
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Minneapolis?
There are approximately 906 recruiting clinical trials in Minneapolis, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Minneapolis pay participants?
Most recruiting trials in Minneapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Minneapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Minneapolis?
The most common conditions under active study in Minneapolis include Acute Myeloid Leukemia (16), Heart Failure (16), Ovarian Cancer (13), Parkinson Disease (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Minneapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Minneapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Minneapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Minneapolis?
Recruiting research sites in Minneapolis include University of Minnesota, Abbott-Northwestern Hospital, Hennepin County Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Minneapolis right now?
The largest active categories in Minneapolis are Cancer & tumors (248), Cardiovascular (67), Neurology & pain (55). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.