Paid Clinical Trials in Minneapolis, MN
As of September 2026, 898 paid clinical trials are recruiting in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Minneapolis offers studies at sites including University of Minnesota for conditions such as Heart Failure, Acute Myeloid Leukemia, Ovarian Cancer, Coronary Artery Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Minneapolis
Trials by drug in Minneapolis
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Newly added in Minneapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Evaluation of Speech and Voice Biomarkers in Association With Burnout
Appetite and Cognition Response to a Breakfast Cereal
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
811 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
Top Research Study Locations in Minneapolis
Researchers run research studies in Minneapolis, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Minnesota | Parkinson Disease, Depression, Amyotrophic Lateral Sclerosis | 294 |
| Abbott-Northwestern Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 78 |
| Hennepin County Medical Center | Stage IVB Prostate Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 65 |
| University of Minnesota/Masonic Cancer Center | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm | 35 |
| Minneapolis Heart Institute Foundation | Coronary Artery Disease, Tricuspid Valve Regurgitation, Cardiovascular Diseases | 34 |
| Minneapolis VA Health Care System, Minneapolis, MN | Amputation, Bipolar Disorder, Spinal Cord Diseases | 29 |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 25 |
| Health Partners Inc | Stage IVB Prostate Cancer AJCC v8, Ovarian Carcinoma, Acral Lentiginous Melanoma | 19 |
| University of Minnesota Medical Center | ADA SCID, Advanced Melanoma, Aortic Stenosis | 17 |
| Masonic Cancer Center | Acute Myeloid Leukemia, Smoking Cessation, Acute Lymphoblastic Leukemia | 15 |
| Minneapolis Heart Institute | Coronary Artery Disease, Cardiovascular Diseases, Heart Diseases | 14 |
| Minneapolis VA Medical Center | Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 | 13 |
| University of Minnesota Masonic Children's Hospital | Hypochondroplasia, Obesity, Fabry Disease | 11 |
| Abbott Northwestern Hospital | AMI, Acute Stroke, Aneurysm Cerebral | 10 |
| Children's Minnesota | Ciliary Body Medulloepithelioma, Craniopharyngioma, Craniopharyngioma, Child | 8 |
| M Health Fairview University of Minnesota Medical Center | Ischemic Stroke, Adamantinomatous Craniopharyngioma, Atrial Fibrillation | 8 |
| Minneapolis VA Health Care System | Heart Failure, Aging Related Cognitive Decline, Chronic Obstructive Pulmonary Disease | 8 |
| Children's Hospitals and Clinics of Minnesota | Cystic Fibrosis, B-cell Acute Lymphoblastic Leukemia, Caregiver Burden | 8 |
| Allina Health Cancer Institute - Abbott Northwestern Hospital | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Advanced Hepatocellular Carcinoma | 7 |
| Masonic Cancer Center at University of Minnesota | Myelodysplastic Syndromes, Acute Leukemia, Acute Myeloid Leukemia | 7 |
| Masonic Cancer Center, University of Minnesota | Adenocarcinoma of Lung, Alcohol-Related Carcinoma, Epithelial Ovarian Cancer | 7 |
| University of Minnesota Medical School | Niemann-Pick Type C Disease, Advanced Solid Tumor, Alopecia | 7 |
| Children's Hospital and Clinics of Minnesota | Neuroblastoma, ALL, AML | 6 |
| Hennepin Healthcare | Acute Respiratory Failure, Awareness, Carcinoma, Hepatocellular | 6 |
| Clinical Research Institute | Migraine, Acute Migraine, Acute Treatment of Migraine | 5 |
Active & Upcoming Studies in Minneapolis (2026)
Recruiting trials in Minneapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (237 active studies)
- Signatera Assessment in Early-Stage Endometrial Cancer · Natera, Inc.
- ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening · VA Office of Research and Development
Cardiovascular (74 active studies)
- Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention · Minneapolis Heart Institute Foundation
- Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients · University of Minnesota
Neurology & pain (55 active studies)
- Simultaneous Engagement of Networks for Alleviating Pain (SENAP) · Phase 1 · University of Minnesota
- Myofunctional Therapy for Obstructive Sleep Apnea · University of Minnesota
Diabetes & metabolic (44 active studies)
- GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward · Phase 4 · University of Minnesota
- Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring. · Phase 2 · HealthPartners Institute
Mental health & behavior (31 active studies)
- Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation · University of Minnesota
- ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening · VA Office of Research and Development
Pediatric (13 active studies)
- NICU-to-Home Dyadic Support for Very Preterm Infants and Families · University of Minnesota
- Magnesium Sulfate in Pediatric Burn Dressing Changes · Phase 1 · Hennepin Healthcare Research Institute
HIV / STI (7 active studies)
- Combating HIV Stigma in Healthcare Settings: A Standardized Patient Approach · University of Minnesota
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
Eye & vision (4 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma · Phase 3 · AbbVie
Vaccines (2 active studies)
- Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID · Phase 3 · Wes Ely
- EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease · Phase 3 · Pfizer
Common conditions studied in Minneapolis
- Heart Failure (18 active studies)
- Acute Myeloid Leukemia (16 active studies)
- Ovarian Cancer (13 active studies)
- Coronary Artery Disease (12 active studies)
- Breast Cancer (11 active studies)
- Endometrial Cancer (11 active studies)
Leading research sponsors in Minneapolis
- University of Minnesota
- National Cancer Institute (NCI)
- Masonic Cancer Center, University of Minnesota
- VA Office of Research and Development
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Minneapolis?
There are approximately 898 recruiting clinical trials in Minneapolis, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Minneapolis pay participants?
Most recruiting trials in Minneapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Minneapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Minneapolis?
The most common conditions under active study in Minneapolis include Heart Failure (18), Acute Myeloid Leukemia (16), Ovarian Cancer (13), Coronary Artery Disease (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Minneapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Minneapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Minneapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Minneapolis?
Recruiting research sites in Minneapolis include University of Minnesota, Abbott-Northwestern Hospital, Hennepin County Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Minneapolis right now?
The largest active categories in Minneapolis are Cancer & tumors (237), Cardiovascular (74), Neurology & pain (55). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.