Clinical Trials at University of Minnesota

As of July 2026, 293 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

293 clinical trials at University of Minnesota

·Clear filters·↓ Download CSV

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

for C3 Glomerulopathy

Drug: Iptacopan

5 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT03955445·Phase 3·Recruiting

Apply to this trial

ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I

for Mucopolysaccharidosis IH/S

2 locations incl. Oakland

Sponsor: Immusoft of CA, Inc.

Sex: All·Age: 10+

Code: NCT05682144·Phase 1·Recruiting

Apply to this trial

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

for E Coli Infections

8 locations incl. Duarte

Sponsor: SNIPR Biome Aps.

Sex: All·Age: 18+

Code: NCT06938867·Phase 1, Phase 2·Recruiting

Apply to this trial

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for Hematologic Malignancy

5 locations incl. Duarte

Sponsor: Tr1X, Inc.

Sex: All·Age: 18+

Code: NCT06462365·Phase 1·Recruiting

Apply to this trial

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

Apply to this trial

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

31 locations incl. Phoenix

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting

Apply to this trial

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

75 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting

Apply to this trial

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

44 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

61 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting

Apply to this trial

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

Apply to this trial

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

Apply to this trial

PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

Apply to this trial

The Myelin Disorders Biorepository Project

for Leukodystrophy

23 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

Apply to this trial

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

Apply to this trial

Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

for Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 30 - 84

Code: NCT03460769·Recruiting

Apply to this trial

Longitudinal Study of the Porphyrias

for Acute Porphyrias

16 locations incl. Birmingham

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting

Apply to this trial

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

32 locations incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting

Apply to this trial

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

Apply to this trial

Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

16 locations incl. Orange

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting·Listed Jun 4, 2026

Apply to this trial

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

Apply to this trial

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for Type 1 Diabetes

Drug: Adalimumab

11 locations incl. San Francisco

Sponsor: City of Hope Medical Center

Sex: All·Age: 9 - 20

Code: NCT07061574·Phase 1, Phase 2·Recruiting

Apply to this trial

Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

for Congenital Disorders of Glycosylation

12 locations incl. San Diego

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: All ages

Code: NCT04199000·Recruiting

Apply to this trial

Childhood Cancer Survivor Study

for Cancer

30 locations incl. Birmingham

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting

Apply to this trial

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

Apply to this trial

A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis

for Immune-related Colitis

9 locations incl. Brainerd

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05726396·Phase 2·Recruiting

Apply to this trial

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

for COPD

25 locations incl. Birmingham

Sponsor: Temple University

Sex: All·Age: 30+

Code: NCT05204888·Recruiting

Apply to this trial

National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

18 locations incl. Los Angeles

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting

Apply to this trial

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

18 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting

Apply to this trial

Diabetes RElated to Acute Pancreatitis and Its Mechanisms

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT05197920·Recruiting

Apply to this trial

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

for Charcot Marie Tooth Disease

18 locations incl. Los Angeles

Sponsor: Michael Shy

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193075·Recruiting

Apply to this trial

Bionic Pancreas in CFRD

for Cystic Fibrosis-related Diabetes

16 locations incl. Aurora

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 14+

Code: NCT06449677·Phase 3·Recruiting

Apply to this trial

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

for Osteonecrosis of the Femoral Head

10 locations incl. Los Angeles

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06123481·Recruiting

Apply to this trial

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

28 locations incl. Berkeley

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting

Apply to this trial

Diagnostic and Therapeutic Applications in Microarrays in Organ Transplantation

for Validation Study of Molecular Diagnostic System

10 locations incl. Birmingham

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT01299168·Recruiting

Apply to this trial

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06296394·Recruiting

Apply to this trial

ALS/MND Natural History Study Data Repository

for ALS

14 locations incl. Loma Linda

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting

Apply to this trial

Closed Loop and Education for Hypoglycemia Awareness Restoration

for Diabetes Mellitus, Type 1

5 locations incl. La Jolla

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06325202·Recruiting

Apply to this trial

Cardiac Structure and Function in MPS

for MPS I

3 locations incl. Orange

Sponsor: Children's Hospital of Orange County

Sex: All·Age: 0 - 99·Accepts healthy volunteers

Code: NCT07361536·Recruiting

Apply to this trial

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

for Lung Transplant

11 locations incl. Los Angeles

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12+

Code: NCT06476132·Phase 2·Recruiting

Apply to this trial