Clinical Trials at University of Minnesota

As of September 2026, 266 paid clinical trials are recruiting at University of Minnesota, located at MINNEAPOLIS VA MEDICAL CENTER, ONE VETERANS DRIVE, MINNEAPOLIS, MN 55417, phone (612) 725-2230 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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268 clinical trials at University of Minnesota

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Evaluation of Decision-Making Fatigue After Traumatic Brain Injury

for TBI (Traumatic Brain Injury)

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07103200·Recruiting·Listed Aug 2025

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Torque Device Evaluation

for Electrophysiology Study

Sites in Minneapolis +1 more location

Sponsor: University of Minnesota

Sex: All·Age: Up to 21

Code: NCT07094256·Recruiting·Listed Jul 2025

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Endogenous Pain Inhibition Deficiency in Chronic TMD Pain

for Chronic Temporomandibular Disorders (TMD)

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 74·Accepts healthy volunteers

Code: NCT06617494·Recruiting·Listed Sep 2024

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Natural History and Structural Functional Relationships in Fabry Renal Disease Treatment Outcomes(Changes)in Fabry Renal Disease Study

for Fabry Disease

2 locations in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 1 - 75

Code: NCT01581424·Recruiting·Listed Apr 2012

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Multicenter ALS Imaging Study

for Amyotrophic Lateral Sclerosis

Sites in Minneapolis +2 more locations

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06735014·Recruiting·Listed Dec 2024

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Stellate Ganglion Block

for Esophagectomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06271707·Phase 4·Recruiting·Listed Feb 2024

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Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

for Tourette Syndrome

Sites in Minneapolis +1 more location

Sponsor: University of Minnesota

Sex: All·Age: 10 - 17

Code: NCT06194305·Phase 2·Recruiting·Listed Jan 2024

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Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting

for Pregnancy Emesis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18+

Code: NCT07378839·Recruiting·Listed Jan 2026

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Minneapolis +35 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

Apply to this trial

Choline and Iron Deficiency

for Pediatric Iron Deficiency

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 5 Months - 7 Months

Code: NCT06527391·Phase 2, Phase 3·Recruiting·Listed Jul 2024

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Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

for Castration Resistant Metastatic Prostate Cancer

Sites in Minneapolis +5 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male·Age: 18 - 90

Code: NCT04363164·Phase 2·Recruiting·Listed Apr 2020

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MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

for Gaucher Disease, Type 3

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05586243·Recruiting·Listed Oct 2022

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Minneapolis +15 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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A Pilot Study of Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in Pulmonary Arterial Hypertension (GUT RESTORE-PAH)

for Pulmonary Arterial Hypertension

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06481852·Phase 1·Recruiting·Listed Jul 2024

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Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

for Oral Leukoplakia

Sites in Minneapolis & Saint Paul

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05727761·Phase 2·Recruiting·Listed Feb 2023

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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

for CBD

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT07069478·Recruiting·Listed Jul 2025

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Cardiac Structure and Function in MPS

for MPS I

Sites in Minneapolis +2 more locations

Sponsor: Children's Hospital of Orange County

Sex: All·Age: 0 - 99·Accepts healthy volunteers

Code: NCT07361536·Recruiting·Listed Jan 2026

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Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder

for Opioid Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07158853·Phase 1·Recruiting·Listed Sep 2025

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Childhood Cancer Survivor Study

for Cancer

Sites in Minneapolis +26 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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A Standardized Counseling Approach to Preoperative Education in Transmasculine Individuals Receiving Gender-affirming Surgery

for Hysterectomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07324967·Recruiting·Listed Jan 2026

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Ostomy Simulation for Patient Education Prior to Urologic Bowel Diversion Surgeries

for Ostomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06583577·Recruiting·Listed Sep 2024

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Cognition and Ultrasound

for Healthy Participants

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07220655·Recruiting·Listed Oct 2025

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Trajectories of Change in Tourette Syndrome

for Tourette Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12 - 17

Code: NCT06679790·Recruiting·Listed Nov 2024

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Targeting Transdiagnostic Self-regulatory Factors and Eating Disorder Pathology Among Adults With BInge-spectrum Eating disOrders: A mHEALTH Interoceptive Exposure Intervention (the Bio-HEALTH Study)

for Eating Disorders

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 64

Code: NCT06631729·Recruiting·Listed Oct 2024

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Individualized Diabetes Education Assisted by CGM (IDEA-CGM)

for Type 2 Diabetes

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06784375·Recruiting·Listed Jan 2025

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Medical Cannabis and Behavior

for Chronic Pain Patients

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 30 - 75

Code: NCT06808048·Recruiting·Listed Feb 2025

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Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

Sites in Minneapolis +2 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543·Recruiting·Listed Jan 2025

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Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

for Gaucher Disease Type I

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT02437396·Recruiting·Listed May 2015

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Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

for Smoking

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18 - 45

Code: NCT04783857·Phase 4·Recruiting·Listed Mar 2021

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JIT: Effect of Pain on DT in TMD

for Temporomandibular Disorder (TMD)

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT06659991·EARLY_Phase 1·Recruiting·Listed Oct 2024

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

Sites in Minneapolis +8 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting·Listed Sep 2019

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A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis

for Immune-related Colitis

Sites in Minneapolis, Brainerd +7 more locations

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05726396·Phase 2·Recruiting·Listed Feb 2023

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Visual Remapping to Aid Reading With Field Loss

for Age-related Macular Degeneration

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT03848663·Recruiting·Listed Feb 2019

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A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures

for Neonatal Seizure

Sites in Minneapolis +1 more location

Sponsor: University of California, San Diego

Sex: All·Age: Up to 1 Month

Code: NCT05610085·Phase 2·Recruiting·Listed Nov 2022

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Pathways Mediating Impaired Postural Control in Parkinson's Disease

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 45 - 80·Accepts healthy volunteers

Code: NCT06464029·Recruiting·Listed Jun 2024

Apply to this trial

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Minneapolis, Saint Louis Park +31 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

Apply to this trial

Evaluation of Microbiota Transplant Therapy in Patients With Alopecia Areata

for Alopecia Areata

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06747611·Phase 2·Recruiting·Listed Dec 2024

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Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

for Suicidal Behavior

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 13 - 21

Code: NCT05652153·Recruiting·Listed Dec 2022

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

Sites in Minneapolis +14 more locations

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting·Listed Mar 2012

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Development of a Novel Evaluation Scale of Mental Body Representation (MBR) for Adults With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07029802·Recruiting·Listed Jun 2025

Apply to this trial