Clinical Trials at University of Minnesota

As of July 2026, 293 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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293 clinical trials at University of Minnesota

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Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

17 locations incl. Tucson

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting

Apply to this trial

Multicenter ALS Imaging Study

for Amyotrophic Lateral Sclerosis

3 locations incl. Gainesville

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06735014·Recruiting

Apply to this trial

Letrozole in Uterine Leiomyosarcoma

for Uterine Leiomyosarcoma

25 locations incl. Aurora

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05649956·Phase 2·Recruiting

Apply to this trial

I CAN DO Surgical ACP

for Surgical Advanced Care Planning

3 locations incl. Irvine

Sponsor: University of California, San Francisco

Sex: All·Age: 65+

Code: NCT06090552·Recruiting

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A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures

for Neonatal Seizure

2 locations incl. San Diego

Sponsor: University of California, San Diego

Sex: All·Age: Up to 1 Month

Code: NCT05610085·Phase 2·Recruiting

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

9 locations incl. San Francisco

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting

Apply to this trial

BEETroot Juice to Reverse Functional Impairment in PAD

for Peripheral Artery Disease

4 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT05624125·Recruiting

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Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

13 locations incl. Tampa

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting

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Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

for Ovarian Cancer

12 locations incl. Miami

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 50 - 74·Accepts healthy volunteers

Code: NCT00539162·Recruiting

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Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

for Castration Resistant Metastatic Prostate Cancer

6 locations incl. San Diego

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male·Age: 18 - 90

Code: NCT04363164·Phase 2·Recruiting

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Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

12 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting

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Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

for Malignant Peripheral Nerve Sheath Tumors

9 locations incl. Tampa

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages

Code: NCT03141021·Recruiting

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Kidney Precision Medicine Project

for Acute Kidney Failure

13 locations incl. Tucson

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting

Apply to this trial

HAPPINESS: cHAnging the Perceived Pain INtEnSity in Populations With Spinal Cord Injury and With Health Disparities: A Feasibility Study

for Spinal Cord Injuries

3 locations incl. Miami

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06140355·Recruiting

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

18 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting

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MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients

for Fanconi Anemia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07649031·Recruiting·Listed Jun 15, 2026

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The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

for Age-related Cognitive Decline

6 locations incl. San Francisco

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 55 - 89

Code: NCT04171323·Recruiting

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Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

for Sepsis

10 locations incl. Gainesville

Sponsor: University of Minnesota

Sex: All·Age: 65+

Code: NCT05758246·Phase 2·Recruiting

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Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

for Tourette Syndrome

2 locations incl. San Diego

Sponsor: University of Minnesota

Sex: All·Age: 10 - 17

Code: NCT06194305·Phase 2·Recruiting

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A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

Apply to this trial

TrialNet Pathway to Prevention of T1D

for Diabetes Mellitus, Type 1

17 locations incl. Orange

Sponsor: University of South Florida

Sex: All·Age: 2 - 45·Accepts healthy volunteers

Code: NCT00097292·Recruiting

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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

Apply to this trial

Myofunctional Therapy for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07301125·Recruiting

Apply to this trial

PASCAL Feasibility Study

for Smoking Cessation

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT07301151·Recruiting

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Glucose and Activity Tracking for Sedentary Behavior Interventions in Older People With Type 2 Diabetes (TRACK T2D)

for Diabetes Mellitus, Type 2

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 55+

Code: NCT07524205·Recruiting

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Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study

for Temporomandibular Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07517172·Recruiting

Apply to this trial

Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Drugs

for Substance Use

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07433712·Recruiting

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Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder

for Opioid Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07158853·Phase 1·Recruiting

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The Black Immigrant Project

for Dementia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07546708·Recruiting

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A Standardized Counseling Approach to Preoperative Education in Transmasculine Individuals Receiving Gender-affirming Surgery

for Hysterectomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07324967·Recruiting

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Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

for Post Traumatic Stress Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18 - 40

Code: NCT07485231·Recruiting

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Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

for Exercise Induced Muscle Damage

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT07219498·Recruiting

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CE-STAND: Cervical Epidural STimulation After Neurologic Damage

for Spinal Cord Injury

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT06410001·Phase 1, Phase 2·Recruiting

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Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

for Persistent Post Concussion Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07246993·Recruiting

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Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling

for Chronic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07103135·Phase 1·Recruiting

Apply to this trial

Assessing Immune Dysfunction in Sepsis

for Sepsis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07154615·Recruiting

Apply to this trial

Elevated Rate Pacing of Cardiac Amyloidosis

for Cardiac Amyloidosis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07583823·Recruiting

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Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting

for Pregnancy Emesis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18+

Code: NCT07378839·Recruiting

Apply to this trial

Just-in-Time Training for Youth Mentors

for Mental Health Issue

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT07129070·Recruiting

Apply to this trial

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

for Laryngeal Dystonia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07443891·Recruiting

Apply to this trial