Clinical Trials at University of Minnesota

As of September 2026, 266 paid clinical trials are recruiting at University of Minnesota, located at MINNEAPOLIS VA MEDICAL CENTER, ONE VETERANS DRIVE, MINNEAPOLIS, MN 55417, phone (612) 725-2230 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

268 clinical trials at University of Minnesota

·Clear filters·

Get a weekly email when new trials open in Minneapolis, MN.

ALS/MND Natural History Study Data Repository

for ALS

Sites in Minneapolis +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

Apply to this trial

Cognitive Function in Rett Syndrome During Trofinetide Treatment

for Rett Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99

Code: NCT06705816·Recruiting·Listed Nov 2024

Apply to this trial

Stimulation of the Larynx to Treat Unexplained Chronic Cough

for Cough

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 88

Code: NCT05273190·Recruiting·Listed Mar 2022

Apply to this trial

A Pilot Study of Efgartigimod for Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)

for Immune-mediated Thrombotic Thrombocytopenic Purpura

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06831058·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

Sites in Minneapolis +4 more locations

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting·Listed Jun 2024

Apply to this trial

Coordinated Reset Deep Brain Stimulation for Essential Tremor

for Essential Tremor

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05897775·Phase 1·Recruiting·Listed Jun 2023

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Minneapolis +51 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

Apply to this trial

Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

for Exercise Induced Muscle Damage

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT07219498·Recruiting·Listed Oct 2025

Apply to this trial

Perception of Speech in Context by Listeners With Healthy and Impaired Hearing

for Hearing

Sites in Minneapolis +1 more location

Sponsor: Marquette University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06465979·Recruiting·Listed Jun 2024

Apply to this trial

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

Sites in Minneapolis +16 more locations

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Imaging Core Aim 2, and Udall Project 2 Aim 2

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT06998303·Recruiting·Listed May 2025

Apply to this trial

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

Sites in Minneapolis, Duluth +34 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting·Listed May 2022

Apply to this trial

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

for Primary Malignant Peripheral Nerve Sheath Tumors

Drug: Mirdametinib

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12+

Code: NCT06693284·EARLY_Phase 1·Recruiting·Listed Nov 2024

Apply to this trial

The COCOA-PAD II Trial

for Peripheral Artery Disease

Sites in Minneapolis +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT04794530·Phase 3·Recruiting·Listed Mar 2021

Apply to this trial

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

for Ovarian Cancer

Sites in Minneapolis +9 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 50 - 74·Accepts healthy volunteers

Code: NCT00539162·Recruiting·Listed Oct 2007

Apply to this trial

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

Sites in Minneapolis +12 more locations

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting·Listed Mar 2020

Apply to this trial

CBIT+TMS R33 Phase

for Tics

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12 - 21

Code: NCT06678737·Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function

for Menopause

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 45 - 55·Accepts healthy volunteers

Code: NCT06490146·Recruiting·Listed Jul 2024

Apply to this trial

Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

for Primary Sclerosing Cholangitis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 76

Code: NCT06197308·EARLY_Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

Cognitive and Affective Processes Online

for Depression

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05736471·Recruiting·Listed Feb 2023

Apply to this trial

Feasibility of Transcranial Focused Ultrasound to Measure Brain Tumor

for Cranial Neurosurgery

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05755399·Recruiting·Listed Mar 2023

Apply to this trial

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

Sites in Minneapolis +31 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting·Listed Mar 2022

Apply to this trial

Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

for Colonic Neoplasms

Sites in Minneapolis +7 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT00843375·Recruiting·Listed Feb 2009

Apply to this trial

Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 89

Code: NCT05893186·EARLY_Phase 1·Recruiting·Listed Jun 2023

Apply to this trial

Aim 3 Particle Swarm Optimization PIGD

for Parkinson's Disease and Parkinsonism

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT05934747·Recruiting·Listed Jul 2023

Apply to this trial

Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

for Peripheral Artery Disease

Sites in Minneapolis +5 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT04228978·Recruiting·Listed Jan 2020

Apply to this trial

BEETroot Juice to Reverse Functional Impairment in PAD

for Peripheral Artery Disease

Sites in Minneapolis +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT05624125·Recruiting·Listed Nov 2022

Apply to this trial

Cognitive Strategies in Early Psychosis 1

for Cognition

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07231497·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Just-in-Time Training for Youth Mentors

for Mental Health Issue

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT07129070·Recruiting·Listed Aug 2025

Apply to this trial

The Cardiovascular Impact of Hot Flushes

for Hot Flashes

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 40 - 70·Accepts healthy volunteers

Code: NCT05251324·Recruiting·Listed Feb 2022

Apply to this trial

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

Sites in Minneapolis, Sartell +71 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial

Kidney Precision Medicine Project

for Acute Kidney Failure

Sites in Minneapolis, Rochester +11 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting·Listed Apr 2020

Apply to this trial

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

Sites in Minneapolis +12 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting·Listed May 2024

Apply to this trial

Microelectrode Recordings From the Vagus Nerve in Awake Humans

for Epilepsy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06016686·Phase 1·Recruiting·Listed Aug 2023

Apply to this trial

SMART Exercise for PAD

for Peripheral Arterial Disease

Sites in Minneapolis +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT06032065·Phase 3·Recruiting·Listed Sep 2023

Apply to this trial

Pathways 2 Success

for Conduct Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 13 - 17

Code: NCT06831123·Phase 1, Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Intracranial Stimulation Mapping In Epilepsy

for Epilepsy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05290610·Recruiting·Listed Mar 2022

Apply to this trial

Udall Project 1 Aim 4

for Parkinsons Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05568199·Recruiting·Listed Oct 2022

Apply to this trial

Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)

for Cannabis Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 15 - 18·Accepts healthy volunteers

Code: NCT06124846·Recruiting·Listed Nov 2023

Apply to this trial

Extracellular Vesicles as Potential Biomarkers and Therapeutic Target in Gaucher Disease

for Gaucher Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05843552·Recruiting·Listed May 2023

Apply to this trial