Clinical Trials at University of Minnesota

As of July 2026, 293 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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Healthy volunteers only

293 clinical trials at University of Minnesota

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Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

for Oral Leukoplakia

2 locations incl. Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05727761·Phase 2·Recruiting

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Personalized Nutrition for Type 2 Diabetes

for Type 2 Diabetes

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06784375·Recruiting

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Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

for Total Shoulder Arthroplasty

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06143306·Phase 4·Recruiting

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Stellate Ganglion Block

for Esophagectomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06271707·Phase 4·Recruiting

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Pathways Mediating Impaired Postural Control in Parkinson's Disease

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 45 - 80·Accepts healthy volunteers

Code: NCT06464029·Recruiting

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Cognition and Ultrasound

for Healthy Participants

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07220655·Recruiting

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Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

for Suicidal Behavior

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 13 - 21

Code: NCT05652153·Recruiting

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CompuFlo CathCheck

for Epidural Placement

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99

Code: NCT06460155·Phase 4·Recruiting

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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

for CBD

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT07069478·Recruiting

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Aim 3 Particle Swarm Optimization PIGD

for Parkinson's Disease and Parkinsonism

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT05934747·Recruiting

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Microelectrode Recordings From the Vagus Nerve in Awake Humans

for Epilepsy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06016686·Phase 1·Recruiting

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Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)

for Cannabis Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 15 - 18·Accepts healthy volunteers

Code: NCT06124846·Recruiting

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Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy

for Neck Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 39

Code: NCT06312696·Recruiting

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Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

for Primary Sclerosing Cholangitis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 76

Code: NCT06197308·EARLY_Phase 1·Recruiting

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Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

for Hypertension

Drug: Empagliflozin

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 60+

Code: NCT06507657·EARLY_Phase 1·Recruiting

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Intestinal Microbiota Transplantation in Patients Undergoing Colon Resection

for Recurrent Clostridioides Difficile Infection

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06370884·Phase 1·Recruiting

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

6 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting

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Udall Project 1 Aim 4

for Parkinsons Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05568199·Recruiting

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Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture

for Hip Fractures

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06278987·Phase 4·Recruiting

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Trajectories of Change in Tourette Syndrome

for Tourette Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12 - 17

Code: NCT06679790·Recruiting

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Modeling Tic Change During Behavior Therapy for Tics

for Chronic Tic Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12 - 21

Code: NCT06270251·Recruiting

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Longitudinal Study of Urea Cycle Disorders

for Brain Diseases, Metabolic, Inborn

12 locations incl. Los Angeles

Sponsor: Andrea Gropman

Sex: All·Age: All ages

Code: NCT00237315·Recruiting

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A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06481852·Phase 1·Recruiting

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Feasibility of Transcranial Focused Ultrasound to Measure Brain Tumor

for Cranial Neurosurgery

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05755399·Recruiting

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Perception of Speech in Context by Listeners With Healthy and Impaired Hearing

for Hearing

2 locations incl. Minneapolis

Sponsor: Marquette University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06465979·Recruiting

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Coordinated Reset Deep Brain Stimulation for Essential Tremor

for Essential Tremor

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05897775·Phase 1·Recruiting

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SMART Exercise for PAD

for Peripheral Arterial Disease

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT06032065·Phase 3·Recruiting

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Extracellular Vesicles as Potential Biomarkers and Therapeutic Target in Gaucher Disease

for Gaucher Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05843552·Recruiting

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Neuroplasticity in RBD

for REM Sleep Behavior Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT05471960·Recruiting

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Cognitive and Affective Processes Online

for Depression

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05736471·Recruiting

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Evaluation of the SCALED (SCaling AcceptabLE cDs)

for Traumatic Brain Injury

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05628207·Recruiting

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Visual Remapping to Aid Reading With Field Loss

for Age-related Macular Degeneration

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT03848663·Recruiting

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To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation

for Central Airway Obstruction

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05881863·Recruiting

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Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

for Gaucher Disease Type I

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT02437396·Recruiting

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Stimulation of the Larynx to Treat Unexplained Chronic Cough

for Cough

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 88

Code: NCT05273190·Recruiting

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Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

for Hodgkin Lymphoma

Drug: Ruxolitinib

6 locations incl. Minneapolis

Sponsor: Veronika Bachanova

Sex: All·Age: 18+

Code: NCT03681561·Phase 1, Phase 2·Recruiting

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Sleep-specific DBS Therapy in Parkinson's Disease

for Deep Brain Stimulation

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05962489·Recruiting

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The COCOA-PAD II Trial

for Peripheral Artery Disease

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT04794530·Phase 3·Recruiting

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Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis

for NASH - Nonalcoholic Steatohepatitis

4 locations incl. San Francisco

Sponsor: University of Minnesota

Sex: All·Age: 30 - 70

Code: NCT03587831·Recruiting

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Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 89

Code: NCT05893186·EARLY_Phase 1·Recruiting

Apply to this trial