Paid Clinical Trials in Minneapolis, MN

As of September 2026, 897 paid clinical trials are recruiting in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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811 clinical trials

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Family, Responsibility, Education, Support, and Health for Food Responsiveness

for Obesity, Childhood

Sites in Minneapolis +1 more location

Sponsor: University of California, San Diego

Sex: All·Age: 7 - 12·Accepts healthy volunteers

Code: NCT06207110·Recruiting·Listed Jan 2024

Apply to this trial

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

for Heart Failure

Sites in Minneapolis, Maplewood +10 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 100

Code: NCT06425848·Recruiting·Listed May 2024

Apply to this trial

Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis

for NASH - Nonalcoholic Steatohepatitis

Sites in Minneapolis +3 more locations

Sponsor: University of Minnesota

Sex: All·Age: 30 - 70

Code: NCT03587831·Recruiting·Listed Jul 2018

Apply to this trial

DESIFOR-EXPAND (MHIF)

for Statin Therapy

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 21+

Code: NCT06804980·Phase 4·Recruiting·Listed Feb 2025

Apply to this trial

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

for Healthy

Sites in Minneapolis +3 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT00785525·Phase 3·Recruiting·Listed Nov 2008

Apply to this trial

International PPB/DICER1 Registry

for Pleuropulmonary Blastoma

1 location in Minneapolis

Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: All·Age: 0 Minutes - 100·Accepts healthy volunteers

Code: NCT03382158·Recruiting·Listed Dec 2017

Apply to this trial

Sodium Glucose Co-Transporter 2 (SGLT2) and STEMI

for Heart Attack

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 18 - 75

Code: NCT05305911·Phase 2·Recruiting·Listed Mar 2022

Apply to this trial

International Ovarian & Testicular Stromal Tumor Registry

for Ovarian Sex-cord Stromal Tumor

1 location in Minneapolis

Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: All·Age: 0 - 100·Accepts healthy volunteers

Code: NCT01970696·Recruiting·Listed Oct 2013

Apply to this trial

Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families

for Racially/Ethnically Diverse Families From Urban Settings

Sites in Minneapolis +1 more location

Sponsor: University of Colorado, Denver

Sex: All·Age: 8 - 18

Code: NCT05744973·Recruiting·Listed Feb 2023

Apply to this trial

Fetoscopic Endoluminal Tracheal Occlusion

for Hernia, DIaphragmatic, Congenital

1 location in Minneapolis

Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: Female·Age: 18+

Code: NCT05771688·Recruiting·Listed Mar 2023

Apply to this trial

Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis

for Myelofibrosis

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 55+

Code: NCT02934477·Recruiting·Listed Oct 2016

Apply to this trial

Assessment of Allogeneic Hematopoietic Cell Transplantation in Medicare Beneficiaries With Multiple Myeloma

for Multiple Myeloma

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT03127761·Recruiting·Listed Apr 2017

Apply to this trial

The HALT Biomarker Study

for Aortic Stenosis

Sites in Minneapolis +2 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65+

Code: NCT04552275·Phase 1·Recruiting·Listed Sep 2020

Apply to this trial

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Minneapolis, Rochester +50 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

Apply to this trial

Augmenting Ankle Plantarflexor Function in Cerebral Palsy

for Cerebral Palsy

1 location in Minneapolis

Sponsor: Northern Arizona University

Sex: All·Age: 8 - 21

Code: NCT05154253·Phase 1·Recruiting·Listed Dec 2021

Apply to this trial

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

Sites in Minneapolis, Saint Cloud +53 more locations

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting·Listed Nov 2020

Apply to this trial

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

Sites in Minneapolis +58 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting·Listed Aug 2016

Apply to this trial

Somatic Mosaicism in Twins Discordant for Childhood Cancer

for Pediatric Central Nervous System Tumor

1 location in Minneapolis

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 18

Code: NCT06054295·Recruiting·Listed Sep 2023

Apply to this trial

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

for Acute Compartment Syndrome

Sites in Minneapolis +3 more locations

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 60

Code: NCT05889559·Recruiting·Listed Jun 2023

Apply to this trial

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Minneapolis +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

Apply to this trial

International Device Assisted Controlled Sequential Elevation CPR Registry

for Cardiac Arrest, Out-Of-Hospital

1 location in Minneapolis

Sponsor: Hennepin Healthcare Research Institute

Sex: All·Age: 18+

Code: NCT05588024·Recruiting·Listed Oct 2022

Apply to this trial

Cortical Spreading Depolarization After Severe Traumatic Brain Injury

for Traumatic Brain Injury

1 location in Minneapolis

Sponsor: Hennepin County Medical Center, Minneapolis

Sex: All·Age: 18+

Code: NCT03321370·Recruiting·Listed Oct 2017

Apply to this trial

Social Support Counseling Intervention for Kidney Transplant Candidates

for Kidney Transplant

1 location in Minneapolis

Sponsor: Hennepin Healthcare Research Institute

Sex: All·Age: 18+

Code: NCT06147076·Recruiting·Listed Nov 2023

Apply to this trial

End-Tidal Oxygen for Intubation in the Emergency Department

for Critical Illness

Sites in Minneapolis +2 more locations

Sponsor: Sydney Local Health District

Sex: All·Age: 18+

Code: NCT06578468·Recruiting·Listed Aug 2024

Apply to this trial

Observational Approach Versus Surgical Intervention for Stones

for Nephrolithiasis

Sites in Minneapolis +1 more location

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 6+

Code: NCT07718802·Recruiting·Listed Jul 2026

Apply to this trial

A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity

for Obesity & Overweight

Drug: Semaglutide

1 location in Minneapolis

Sponsor: Gila Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT07728383·Phase 4·Recruiting·Listed Jul 27, 2026

Apply to this trial

Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention

for Coronary Artery Disease

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 22+

Code: NCT07691502·Recruiting·Listed Jul 2026

Apply to this trial

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for Acute Migraine

Drug: Elismetrep

Sites in Minneapolis +112 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18+

Code: NCT07674654·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Semaglutide

Sites in Minneapolis +63 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662213·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

for Obesity

Sites in Minneapolis, Mankato +72 more locations

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All·Age: 18 - 79·Accepts healthy volunteers

Code: NCT07654374·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

OPN Balloon for SAFE Recanalization of Calcified Coronary Lesions

for Coronary Arterial Disease (CAD)

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 18+

Code: NCT07646444·Recruiting·Listed Jun 2026

Apply to this trial

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Minneapolis +10 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Recruiting·Listed May 2026

Apply to this trial

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old

for Congenital Adrenal Hyperplasia

Sites in Minneapolis +10 more locations

Sponsor: Neurocrine Switzerland GmbH

Sex: All·Age: 3 Months - 47 Months

Code: NCT07536269·Phase 2·Recruiting·Listed Apr 2026

Apply to this trial

Microbiome-targeted Diet Therapy in Ulcerative Colitis

for Ulcerative Colitis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07520461·Recruiting·Listed Apr 2026

Apply to this trial

VDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)

for Tricuspid Valve Regurgitation

1 location in Minneapolis

Sponsor: VDyne, Inc.

Sex: All·Age: 18+

Code: NCT07516444·Recruiting·Listed Apr 2026

Apply to this trial

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

Drug: Nerandomilast

Sites in Minneapolis +29 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

EMS-Initiated Buprenorphine

for Opioid Use Disorder

Sites in Minneapolis +2 more locations

Sponsor: Yale University

Sex: All·Age: All ages

Code: NCT07475728·Recruiting·Listed Mar 2026

Apply to this trial

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

Sites in Minneapolis, Burnsville +78 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

Sites in Minneapolis +6 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for Stomatitis

Sites in Minneapolis +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07357597·Phase 4·Recruiting·Listed Jan 2026

Apply to this trial