Paid Clinical Trials in Minneapolis, MN

As of September 2026, 897 paid clinical trials are recruiting in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

811 clinical trials

Get a weekly email when new trials open in Minneapolis, MN.

A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach

for Carotid Artery Diseases

Sites in Minneapolis +7 more locations

Sponsor: InspireMD

Sex: All·Age: 18 - 79

Code: NCT06653387·Recruiting·Listed Oct 2024

Apply to this trial

US National TOP Registry

for Lung Transplant

Sites in Minneapolis +6 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT06513091·Recruiting·Listed Jul 2024

Apply to this trial

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

for Beta-Thalassemia

Sites in Minneapolis +5 more locations

Sponsor: Genetix Biotherapeutics Inc.

Sex: All·Age: All ages

Code: NCT06271512·Recruiting·Listed Feb 2024

Apply to this trial

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

Sites in Minneapolis, Rochester +7 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting·Listed Nov 2021

Apply to this trial

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

for E Coli Infections

Sites in Minneapolis +7 more locations

Sponsor: SNIPR Biome Aps.

Sex: All·Age: 18+

Code: NCT06938867·Phase 1, Phase 2·Recruiting·Listed Apr 2025

Apply to this trial

Evaluation of Accuracy of the Owlet OSS 3.0 Sensor in the Neonatal Population

for Pulse Oximeter Validation

Sites in Minneapolis +1 more location

Sponsor: Owlet Baby Care, Inc.

Sex: All·Age: 0 Days - 28 Days

Code: NCT06771206·Recruiting·Listed Jan 2025

Apply to this trial

Physio-Anatomy Clinical Data Collection Study

for Coronary Stenosis

Sites in Minneapolis +5 more locations

Sponsor: Gentuity, LLC

Sex: All·Age: 18+

Code: NCT05312164·Recruiting·Listed Apr 2022

Apply to this trial

Parent-Child EF Intervention

for Cognitive Intervention to Promote Healthy Development of Executive Function (EF) Skills in Young Children

Sites in Minneapolis +1 more location

Sponsor: Koronis Biomedical Technologies

Sex: All·Age: 2 - 5·Accepts healthy volunteers

Code: NCT06924307·Recruiting·Listed Apr 2025

Apply to this trial

Brain Training for Substance Use Disorders

for Opioid Use Disorder

1 location in Minneapolis

Sponsor: Neurotype Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06870110·Recruiting·Listed Mar 2025

Apply to this trial

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for Solid Tumors

Sites in Minneapolis +7 more locations

Sponsor: Adcentrx Therapeutics

Sex: All·Age: 18+

Code: NCT06710379·Phase 1·Recruiting·Listed Nov 2024

Apply to this trial

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for Hematologic Malignancy

Sites in Minneapolis +4 more locations

Sponsor: Tr1X, Inc.

Sex: All·Age: 18+

Code: NCT06462365·Phase 1·Recruiting·Listed Jun 2024

Apply to this trial

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

for Diffuse Midline Glioma, H3 K27M-Mutant

1 location in Minneapolis

Sponsor: OX2 Therapeutics

Sex: All·Age: 2 - 25

Code: NCT06305910·Phase 1·Recruiting·Listed Mar 2024

Apply to this trial

Capturing Food Intake in Patients Undergoing Radiation Therapy for Cancer

for Cancer

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07682714·Recruiting·Listed Jul 2026

Apply to this trial

Feasibility of a Remotely Delivered Step Count Intervention in Chronic Stroke

for Stroke

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07649135·Recruiting·Listed Jun 2026

Apply to this trial

Tailor VHA HH Bundle for Acute Mental Health Care

for Hand Hygiene Compliance

Sites in Minneapolis +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 90

Code: NCT07607145·Recruiting·Listed May 2026

Apply to this trial

MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients

for Fanconi Anemia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07649031·Recruiting·Listed Jun 2026

Apply to this trial

Fast-Her: Fasting Effects on Breast Cancer Treatment

for Metastatic Breast Cancer

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07624617·Recruiting·Listed Jun 2026

Apply to this trial

Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

Sites in Minneapolis +15 more locations

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting·Listed Jun 2026

Apply to this trial

The SEAS Study: Sensory Engagement and Activation During Noninvasive Stimulation

for Healthy Adult Participants

3 locations in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07606573·Recruiting·Listed May 2026

Apply to this trial

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

for Coronary Artery Disease

Sites in Minneapolis +16 more locations

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07559903·Recruiting·Listed Apr 2026

Apply to this trial

Adapt NK for High Risk Myeloid Diseases as Bridge to Allo HSCT

for Relapsed Adult AML

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT07591649·Phase 1, Phase 2·Recruiting·Listed May 2026

Apply to this trial

Elevated Rate Pacing of Cardiac Amyloidosis

for Cardiac Amyloidosis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07583823·Recruiting·Listed May 2026

Apply to this trial

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Ribociclib

Sites in Minneapolis, Saint Louis Park +174 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07391774·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

for Astrocytoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT07560865·Phase 1·Recruiting·Listed May 2026

Apply to this trial

Glucose and Activity Tracking for Sedentary Behavior Interventions in Older People With Type 2 Diabetes (TRACK T2D)

for Diabetes Mellitus, Type 2

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 55+

Code: NCT07524205·Recruiting·Listed Apr 2026

Apply to this trial

Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UH3

for Chronic Pain

1 location in Minneapolis

Sponsor: Minneapolis Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT07541599·Recruiting·Listed Apr 2026

Apply to this trial

Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study

for Temporomandibular Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07517172·Recruiting·Listed Apr 2026

Apply to this trial

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Minneapolis, Saint Louis Park +204 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 65+

Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

The Black Immigrant Project

for Dementia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07546708·Recruiting·Listed Apr 2026

Apply to this trial

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for Ampulla of Vater Carcinoma

Sites in Minneapolis, Saint Louis Park +346 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283939·Recruiting·Listed Dec 2025

Apply to this trial

GTB-5550 in Advanced Solid Tumors

for Tri-specific Killer Engager

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT07541573·Phase 1·Recruiting·Listed Apr 2026

Apply to this trial

Improving Barriers to Care Access for Children With Autism and Related Needs Via Telehealth for Evaluation, Care Navigating, and Caregiver Coaching

for Autism Spectrum Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 1+

Code: NCT07520838·Recruiting·Listed Apr 2026

Apply to this trial

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

for AML

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 2 - 75

Code: NCT07493538·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Minneapolis, Saint Louis Park +1087 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

for Post Traumatic Stress Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18 - 40

Code: NCT07485231·Recruiting·Listed Mar 2026

Apply to this trial

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Minneapolis, Saint Louis Park +625 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Drugs

for Substance Use

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07433712·Recruiting·Listed Feb 2026

Apply to this trial

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

Sites in Minneapolis, Saint Louis Park +261 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Minneapolis, Saint Louis Park +923 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

Apply to this trial

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

Sites in Minneapolis, Saint Louis Park +446 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015

Apply to this trial