MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT07649031
Status
Recruiting
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Conditions

  • Fanconi Anemia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • MRIs — DIAGNOSTIC_TEST
    mMRI and ddMRI

Study Details

This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions in Fanconi Anemia patients.

Key Dates

Start date
May 25, 2026
Status verified
Jun 2026
Primary completion
May 31, 2030
Completion
May 31, 2030

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: FA patients with a history of HNSCC
    This group will receive both mMRI and ddMRI, with an exam, every 3-4 months for 2 years (up to 16 scan (+exam) visits).
  • Arm: FA patients with no history of HNSCC
    This group will receive two scans each of mMRI and ddMRI, with an exam, one year apart (up to 4 scan (+exam) visits).

Primary Outcome Measure

sensitivity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. [ Time Frame: Immediately after MRI ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaMinneapolisMinnesota55455
Carla Campbell, BS
[email protected]
612-625-6976

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By research site
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