Paid Clinical Trials in Minnesota

Minnesota has 2,231 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,939 clinical trials

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A Study of JNJ-1761981 in Participants With Solid Tumors

for Neoplasms

Sites in Rochester +3 more locations

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT07525141·Phase 1·Recruiting·Listed Apr 2026

Apply to this trial

A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients

for High-Risk Neuroblastoma

Sites in Minneapolis +4 more locations

Sponsor: Renaissance Pharma Ltd.

Sex: All·Age: 18 Months - 18

Code: NCT07549321·Phase 2, Phase 3·Recruiting·Listed Apr 2026

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Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel)

for Healthy Participants

1 location in Saint Paul

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: Female·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07539090·Phase 1·Recruiting·Listed Apr 2026

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EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety

for Alport Syndrome, X-Linked

Sites in Minneapolis +7 more locations

Sponsor: Eloxx Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07523581·Phase 2·Recruiting·Listed Apr 2026

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ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

for Dravet Syndrome

Sites in Rochester +4 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 12

Code: NCT07531745·Phase 1, Phase 2·Recruiting·Listed Apr 2026

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Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

for Warm Autoimmune Hemolytic Anemia (WAIHA)

Sites in Rochester +1 more location

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT07549698·Phase 1, Phase 2·Recruiting·Listed Apr 2026

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A Study of JPH034 in Healthy Adult Participants

for Health Adult Subjects

1 location in Dilworth

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07534657·Phase 1·Recruiting·Listed Apr 2026

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Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for Lung Cancer

Sites in Rochester +7 more locations

Sponsor: Vergent Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07499674·Phase 3·Recruiting·Listed Mar 2026

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Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)

for Orthostatic Hypotension

1 location in Rochester

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07502599·Recruiting·Listed Mar 2026

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A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis

for Neurotrophic Keratitis

Sites in Minneapolis +2 more locations

Sponsor: TearSolutions, Inc.

Sex: All·Age: 18+

Code: NCT07568730·Phase 2·Recruiting·Listed May 2026

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A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

for Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS)

Drug: NIO752

Sites in Rochester +4 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 41 - 81

Code: NCT07498426·Phase 3·Recruiting·Listed Mar 2026

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A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

for Breast Cancer

Drug: Ribociclib

Sites in Marshall +9 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07405801·Phase 2·Recruiting·Listed Feb 2026

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A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

for Primary Immune Thrombocytopenia (ITP)

Drug: Ianalumab

Sites in Rochester +12 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07421167·Phase 2·Recruiting·Listed Feb 2026

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A Phase 2/3 Study on the Efficacy and Safety of Mangaciclanol for Contrast-Enhanced MRI of CNS or Body in Adult Patients

for Known or Highly Suspected Central Nervous System (CNS) Lesion

Sites in Rochester +1 more location

Sponsor: GE Healthcare

Sex: All·Age: 18+

Code: NCT07472491·Phase 2, Phase 3·Recruiting·Listed Mar 2026

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A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma (PDAC)

Sites in Rochester +5 more locations

Sponsor: BicycleTx Limited

Sex: All·Age: 18+

Code: NCT07450859·Phase 2·Recruiting·Listed Mar 2026

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Water Vapor Ablation for Prostate Cancer: Long-Term Registry

for Prostate Cancer

Sites in Woodbury +3 more locations

Sponsor: Francis Medical Inc.

Sex: Male·Age: All ages

Code: NCT07455058·Recruiting·Listed Mar 2026

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Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for Advanced Solid Tumors

Drug: Ivonescimab

Sites in Saint Paul +8 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07397338·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for Advanced Solid Tumor, Adult

Sites in Rochester +14 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07361562·Phase 1·Recruiting·Listed Jan 2026

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A Study of Mirikizumab Solution (LY3074828) in Healthy Participants

for Healthy

Sites in Dilworth +4 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07446101·Phase 1·Recruiting·Listed Mar 2026

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Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

for Colorectal Anastomosis

Sites in Rochester +8 more locations

Sponsor: Medtronic - MITG

Sex: All·Age: 18+

Code: NCT07351071·Recruiting·Listed Jan 2026

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A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for FGFR2 Gene Fusion/Rearrangement

Drug: Lirafugratinib

Sites in Rochester +7 more locations

Sponsor: Elevar Therapeutics

Sex: All·Age: 18+

Code: NCT07359820·Phase 2·Recruiting·Listed Jan 2026

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A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants

for Healthy Participants

Drug: Povorcitinib

1 location in Dilworth

Sponsor: Incyte Corporation

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07588139·Phase 1·Recruiting·Listed May 2026

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How's Your Balance?

for Balance Assessment

1 location in Saint Paul

Sponsor: RxFunction Inc.

Sex: All·Age: 20+·Accepts healthy volunteers

Code: NCT07412145·Recruiting·Listed Feb 2026

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MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

for Sepsis

Sites in Rochester +2 more locations

Sponsor: Health Discovery Labs

Sex: All·Age: 18 - 85

Code: NCT07362862·Recruiting·Listed Jan 2026

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A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Rochester +20 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

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CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

for FIGO Stage III and IV Ovarian Cancer

Sites in Rochester +6 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18 - 75

Code: NCT07322094·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults

for Neuropathic Pain

1 location in Saint Paul

Sponsor: Alcamena Stem Cell Therapeutics

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07363395·Phase 1·Recruiting·Listed Jan 2026

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A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

for Alpha-1 Antitrypsin Deficiency (AATD)

Sites in Rochester +3 more locations

Sponsor: Tessera Therapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT07227207·Phase 1, Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

for Diffuse Cutaneous Systemic Sclerosis

Sites in Minneapolis +22 more locations

Sponsor: Mediar Therapeutics

Sex: All·Age: 18+

Code: NCT07287670·Phase 2·Recruiting·Listed Dec 2025

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A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Coon Rapids +8 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218341·Phase 4·Recruiting·Listed Oct 2025

Apply to this trial

Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia

for Fibromyalgia

Sites in Minneapolis +7 more locations

Sponsor: SPIRE Therapeutics Inc.

Sex: All·Age: 22+

Code: NCT07226648·Recruiting·Listed Nov 2025

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A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for Renal Cell Carcinoma

Sites in Saint Louis Park +9 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07227402·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Evaluation of the Q-Pad hrHPV Test System for Identifying Precancer

for HPV Infection

Sites in Minneapolis +2 more locations

Sponsor: Qurasense

Sex: Female·Age: 25+·Accepts healthy volunteers

Code: NCT07281599·Recruiting·Listed Dec 2025

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xDot Access Management System Early Feasibility Study

for Vascular Closure Devices

Sites in Saint Cloud +4 more locations

Sponsor: xDot Medical, Inc

Sex: All·Age: 18+

Code: NCT07464353·Recruiting·Listed Mar 2026

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Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)

for Long QT Syndrome (LQTS) 2

Sites in Rochester +8 more locations

Sponsor: Thryv Therapeutics, Inc.

Sex: All·Age: 15+

Code: NCT07277582·Phase 2, Phase 3·Recruiting·Listed Dec 2025

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A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

for Chronic Lymphocytic Leukemia

Drug: Emavusertib

Sites in Rochester +5 more locations

Sponsor: Curis, Inc.

Sex: All·Age: 18+

Code: NCT07271667·Phase 2·Recruiting·Listed Dec 2025

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A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

for Depressive Disorder, Major

Sites in Rochester +9 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 12 - 17

Code: NCT07227454·Phase 3·Recruiting·Listed Nov 2025

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A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

for Platinum-resistant Ovarian Cancer

Sites in Rochester +6 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: Female·Age: 18+

Code: NCT07226427·Phase 1·Recruiting·Listed Nov 2025

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Establishing the Preliminary Utility of a Novel Pediatric Manual Mobile Standing Wheelchair

for Spina Bifida

1 location in Saint Paul

Sponsor: Optimal Mobility, Inc

Sex: All·Age: 8 - 17

Code: NCT07290556·Recruiting·Listed Dec 2025

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TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

for Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy

Drug: Nucresiran

Sites in Rochester +9 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07223203·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial