Paid Clinical Trials in Minnesota

Minnesota has 2,230 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,932 clinical trials

Phase 1 Study of CLR 125 in Triple Negative Breast Cancer

for Breast Cancer

Sites in Rochester +3 more locations

Sponsor: Cellectar Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07311993·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

for Advanced Pheochromocytoma and Paraganglioma

Sites in Rochester +8 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07282587·Phase 2·Recruiting·Listed Dec 2025

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A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for Renal Cell Carcinoma

Sites in Saint Louis Park +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07227402·Phase 3·Recruiting·Listed Nov 2025

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AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)

for Metastatic Castration Resistant Prostate Cancer (mCRPC)

Sites in Minneapolis +8 more locations

Sponsor: Arsenal Biosciences, Inc.

Sex: Male·Age: 18+

Code: NCT07285694·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia

for Fibromyalgia

Sites in Minneapolis +7 more locations

Sponsor: SPIRE Therapeutics Inc.

Sex: All·Age: 22+

Code: NCT07226648·Recruiting·Listed Nov 2025

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A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

for Platinum-resistant Ovarian Cancer

Sites in Rochester +6 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: Female·Age: 18+

Code: NCT07226427·Phase 1·Recruiting·Listed Nov 2025

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A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Coon Rapids +8 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218341·Phase 4·Recruiting·Listed Oct 2025

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Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)

for Blood Pressure

Sites in Rochester +5 more locations

Sponsor: Biobeat Technologies Ltd.

Sex: All·Age: 18+

Code: NCT07240831·Recruiting·Listed Nov 2025

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Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo Nodularis

for Prurigo Nodularis (PN)

Sites in New Brighton +9 more locations

Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07236099·Phase 2·Recruiting·Listed Nov 2025

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C. Difficile Toxin Levels in Stool From Healthy Individuals Following Standard of Care Antibiotic Treatment for CDI.

for Clostridioides Difficile Infection Recurrence

Sites in Rochester +3 more locations

Sponsor: Bactolife A/S

Sex: All·Age: 18+

Code: NCT07250724·Recruiting·Listed Nov 2025

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Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness

for Pulmonary Embolism Acute

Sites in Saint Cloud +5 more locations

Sponsor: Angiodynamics, Inc.

Sex: All·Age: 18+

Code: NCT07280247·Recruiting·Listed Dec 2025

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The Effect of Cosmetic Formulations on the Appearance of Grey Hair.

for Hair Graying

1 location in Minneapolis

Sponsor: Unilever R&D

Sex: All·Age: 25 - 60

Code: NCT07280676·Recruiting·Listed Dec 2025

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TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

for Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy

Drug: Nucresiran

Sites in Rochester +8 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07223203·Phase 3·Recruiting·Listed Oct 2025

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A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)

for Stargardt Disease

Sites in Rochester +6 more locations

Sponsor: AAVantgarde Bio Srl

Sex: All·Age: 8 - 55

Code: NCT07161544·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in Minneapolis +7 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]

for Rheumatoid Arthritis (RA)

1 location in Minneapolis

Sponsor: SecondWave Systems Inc.

Sex: All·Age: 18+

Code: NCT07163221·Recruiting·Listed Sep 2025

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A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

for Catecholaminergic Polymorphic Ventricular Tachycardia

Sites in Rochester +3 more locations

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 7+

Code: NCT07148089·Phase 1·Recruiting·Listed Aug 2025

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The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

for Metastatic Solid Tumors

1 location in Rochester

Sponsor: New Phase Ltd.

Sex: All·Age: 18+

Code: NCT07224464·Recruiting·Listed Nov 2025

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AERA Pediatrics Registry

for Dysfunction of Eustachian Tube

Sites in Minneapolis +8 more locations

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: Up to 18

Code: NCT07071298·Recruiting·Listed Jul 2025

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A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

for Congenital Adrenal Hyperplasia

Sites in Minneapolis +8 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 1 - 17

Code: NCT07159841·Phase 2, Phase 3·Recruiting·Listed Sep 2025

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A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

for Dilated Cardiomyopathy (DCM)

Sites in Rochester +2 more locations

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07137338·Phase 1·Recruiting·Listed Aug 2025

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Actinium Therapy for Late-stage Aggressive Sarcomas

for Advanced Soft Tissue Sarcoma

Sites in Rochester +4 more locations

Sponsor: Ratio Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07156565·Phase 1·Recruiting·Listed Sep 2025

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A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia

for Congenital Adrenal Hyperplasia

Sites in Rochester, Minneapolis +8 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07144163·Phase 3·Recruiting·Listed Aug 2025

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A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

for Von Willebrand Disease, Type 3

Sites in Minneapolis +4 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 1 Month+

Code: NCT06998524·Phase 3·Recruiting·Listed May 2025

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A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

for Immunoglobulin A Nephropathy (IgAN)

Sites in Edina +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07146906·Phase 2·Recruiting·Listed Aug 2025

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Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for Weight Regain

Sites in Rochester +8 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07015424·Recruiting·Listed Jun 2025

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A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

for Niemann-Pick Type C Disease

Sites in Rochester, Minneapolis +3 more locations

Sponsor: Azafaros B.V.

Sex: All·Age: 4+

Code: NCT07082725·Phase 3·Recruiting·Listed Jul 2025

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Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

for Epithelial Ovarian Cancer

Sites in Minneapolis +7 more locations

Sponsor: Imunon

Sex: Female·Age: 18+

Code: NCT06915025·Phase 3·Recruiting·Listed Apr 2025

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A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

for Niemann-Pick Type C Disease

Sites in Rochester, Minneapolis +3 more locations

Sponsor: Azafaros B.V.

Sex: All·Age: 4+

Code: NCT07054515·Phase 3·Recruiting·Listed Jul 2025

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The TRICURE EFS Study

for Tricuspid Valve Regurgitation

Sites in Minneapolis +7 more locations

Sponsor: TRiCares

Sex: All·Age: 18+

Code: NCT06506942·Recruiting·Listed Jul 2024

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Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

for Tricuspid Regurgitation

Sites in Rochester +9 more locations

Sponsor: Laplace Interventional, Inc

Sex: All·Age: 18 - 90

Code: NCT06183684·Recruiting·Listed Dec 2023

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An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

for Chronic Kidney Disease (CKD)

Sites in Minneapolis +6 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT05106387·Recruiting·Listed Nov 2021

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Clinical Course Of Disease In Participants With FA-CM

for Friedreich Ataxia

Sites in Rochester +7 more locations

Sponsor: Lexeo Therapeutics

Sex: All·Age: 6+

Code: NCT06865482·Recruiting·Listed Mar 2025

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FIBERGRAFT Aeridyan Posterolateral Fusion Study

for Degenerative Spine Disease

Sites in Rochester +7 more locations

Sponsor: DePuy Synthes Products, Inc.

Sex: All·Age: 18+

Code: NCT07059065·Recruiting·Listed Jul 2025

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Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

for Cancer

Sites in Minneapolis, Coon Rapids +4 more locations

Sponsor: Helio Genomics

Sex: All·Age: 18+

Code: NCT05181826·Recruiting·Listed Jan 2022

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The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study

for Relapsing Remitting Multiple Sclerosis

Sites in Plymouth +7 more locations

Sponsor: SetPoint Medical Corporation

Sex: All·Age: 22 - 50

Code: NCT06796504·Recruiting·Listed Jan 2025

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FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

for Non-Small Cell Lung Cancer

Sites in Minneapolis +4 more locations

Sponsor: Fate Therapeutics

Sex: All·Age: 18+

Code: NCT07216105·Phase 1·Recruiting·Listed Oct 2025

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Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis

for Lupus Nephritis (LN)

Sites in Rochester +1 more location

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 60

Code: NCT06975787·Phase 1·Recruiting·Listed May 2025

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Safety of HRX215 in Patients After Minor and Major Liver Resection

for Liver Resection

Sites in Rochester +2 more locations

Sponsor: HepaRegeniX GmbH

Sex: All·Age: 18 - 75

Code: NCT06638502·Phase 1, Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for Pancreatic Ductal Adenocarcinoma

Sites in Rochester +8 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06562192·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial