Paid Clinical Trials in Minnesota

Minnesota has 2,367 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,367 clinical trials

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A Pilot Study of a Portable Head-Only MRI Scanner

for Brain Imaging

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07444034·Recruiting

Apply to this trial

A Randomized Controlled Trial of Menopausal Tool/App for Women

for Menopausal Symptoms

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 24 - 80

Code: NCT06919887·Enrolling By Invitation

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

for Cervical Cancer

92 locations incl. Phoenix

Sponsor: Pfizer

Sex: Female·Age: 18+

Code: NCT06952660·Phase 4·Recruiting

Apply to this trial

Multi-Cancer Detection Observational Cohort Study

for Cancer

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06962995·Recruiting

Apply to this trial

Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.

for IBD (Inflammatory Bowel Disease)

1 location in Minneapolis

Sponsor: DiaSorin Inc.

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT07471490·Enrolling By Invitation

Safety of HRX215 in Patients After Minor and Major Liver Resection

for Liver Resection

1 location in Rochester

Sponsor: HepaRegeniX GmbH

Sex: All·Age: 18 - 75

Code: NCT06638502·Phase 1, Phase 2·Recruiting

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Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Drug: Rilvegostomig

35 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06921785·Phase 3·Recruiting

Apply to this trial

Tube Size Randomized Trial During Emergency Tracheal Intubation

for Acute Respiratory Failure

7 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06939361·Enrolling By Invitation

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

for Intracerebral Hemorrhage

48 locations incl. Birmingham

Sponsor: Joseph Broderick, MD

Sex: All·Age: 18 - 80

Code: NCT07227246·Phase 3·Recruiting

Apply to this trial

Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

13 locations incl. Scottsdale

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting

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A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

for Advanced Lung Cancer

16 locations incl. Phoenix

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06892548·Phase 1, Phase 2·Recruiting

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A Pilot Study of Efgartigimod for Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)

for Immune-mediated Thrombotic Thrombocytopenic Purpura

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06831058·Phase 2·Recruiting

Apply to this trial

Tirzepatide in PWS, HO and GNSO

for Prader-Willi Syndrome

Drug: Tirzepatide

3 locations incl. Saint Paul

Sponsor: Grace Kim

Sex: All·Age: 18 - 26

Code: NCT06901245·Phase 4·Recruiting

Apply to this trial

Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

for Kidney Calculi

16 locations incl. Phoenix

Sponsor: Avvio Medical

Sex: All·Age: 21+

Code: NCT06942949·Recruiting

Apply to this trial

ACL Reconstruction Rehabilitation With Exercise and Psychological Support

for Anterior Cruciate Ligament Reconstruction Rehabilitation

1 location in Bloomington

Sponsor: HealthPartners Institute

Sex: All·Age: 15 - 21

Code: NCT06991192·Recruiting

Apply to this trial

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

13 locations incl. Los Angeles

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting

Apply to this trial

Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy

for Breast Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06953245·Recruiting

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Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06918132·Phase 2·Recruiting

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Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

for Solid Tumors

6 locations incl. Pheonix

Sponsor: Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.

Sex: All·Age: 18 - 75

Code: NCT06963281·Phase 1·Recruiting

Apply to this trial

Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

Apply to this trial

AI Noise Reduction in Phonak Hearing Aids

for Hearing Loss

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 110

Code: NCT06743295·Recruiting

Apply to this trial

Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

40 locations incl. Ames

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06232044·Phase 1, Phase 2·Recruiting

Apply to this trial

BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Sonrotoclax

7 locations incl. Phoenix

Sponsor: Christine Ryan

Sex: All·Age: 18+

Code: NCT06854003·Phase 2·Recruiting

Apply to this trial

Breastmilk in Response to a Bout of Exercise

for Infant Development

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06892483·Recruiting

Apply to this trial

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

for Acute Respiratory Failure

9 locations incl. Chicago

Sponsor: Brian Driver

Sex: All·Age: 18+

Code: NCT06934876·Recruiting

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

23 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting

Apply to this trial

Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain

for Pain, Chronic

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 65+

Code: NCT06837857·Phase 2·Recruiting

Apply to this trial

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

for Tumor Hyperinsulinism (Tumor HI)

8 locations incl. Chicago

Sponsor: Rezolute

Sex: All·Age: 18+

Code: NCT06881992·Phase 3·Recruiting

Apply to this trial

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

Apply to this trial

An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors

for Childhood Malignant Solid Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 6 Months - 17

Code: NCT06915727·Phase 3·Recruiting

Apply to this trial

American Indian Smokefree Native RCT

for Smoking Cessation

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06544811·Recruiting

Apply to this trial

Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

16 locations incl. Burbank

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting

Apply to this trial

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

for Cardiac Surgery With Cardiopulmonary Bypass

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06895213·Recruiting

Apply to this trial

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for Lymphoma, Large B-Cell, Diffuse

Drug: Polatuzumab Vedotin

70 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06890884·Phase 2·Recruiting

Apply to this trial

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

for Ovarian Cancer

16 locations incl. Birmingham

Sponsor: Corcept Therapeutics

Sex: Female·Age: 18+

Code: NCT06906341·Phase 2·Recruiting

Apply to this trial

Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

for Visual Snow Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06961864·Recruiting

Apply to this trial

An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

for Lennox Gastaut Syndrome

20 locations incl. Little Rock

Sponsor: Epygenix

Sex: All·Age: 2 - 55

Code: NCT05066217·Phase 3·Recruiting

Apply to this trial

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

Apply to this trial

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

for ALS

10 locations incl. La Jolla

Sponsor: Amylyx Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06665165·Phase 1·Recruiting

Apply to this trial

CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)

for Recurrent Pericarditis

21 locations incl. Phoenix

Sponsor: Cardiol Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06708299·Phase 3·Recruiting

Apply to this trial