Paid Clinical Trials in Missouri

Missouri has 1,964 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,743 clinical trials

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

for Bipolar I Disorder

Drug: Icalcaprant

Sites in Saint Charles +32 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06696755·Phase 2·Recruiting·Listed Nov 2024

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A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

for Carcinoma, Non-small-Cell Lung

Drug: Amivantamab

Sites in St Louis +13 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05498428·Phase 2·Recruiting·Listed Aug 2022

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A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Sites in St Louis, Columbia +39 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 12+

Code: NCT06338995·Phase 3·Recruiting·Listed Apr 2024

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SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

Sites in St Louis +41 more locations

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting·Listed Mar 2022

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

Sites in St Louis +52 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting·Listed May 2025

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SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

Sites in St Louis, Overland Park +62 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting·Listed Jul 2023

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

Sites in St Louis +52 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting·Listed May 2025

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sites in Kansas City +31 more locations

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting·Listed Jul 2025

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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

Sites in St Louis, Kansas City +81 more locations

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting·Listed Dec 2024

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

Sites in St Louis, Kansas City +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for Non-small Cell Lung Cancer

Drug: Relatlimab

Sites in Kansas City +37 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06561386·Phase 3·Recruiting·Listed Aug 2024

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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

for Inflammatory Bowel Diseases

Sites in Bridgeton +24 more locations

Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Sex: All·Age: 18 - 85

Code: NCT06226883·Phase 2·Recruiting·Listed Jan 2024

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

Sites in St Louis +39 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting·Listed Jul 2023

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A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

for Chronic Obstructive Pulmonary Disease

Sites in St Louis, Chesterfield +61 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 40 - 90

Code: NCT05878769·Phase 3·Recruiting·Listed May 2023

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Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

for Non-small Cell Lung Cancer

Sites in Columbia, Fenton +37 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712316·Phase 2, Phase 3·Recruiting·Listed Dec 2024

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Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for Amyloidosis

Drug: Acoramidis

Sites in St Louis, Kansas City +37 more locations

Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All·Age: 18 - 75

Code: NCT06563895·Phase 3·Recruiting·Listed Aug 2024

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Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for Prostate Cancer

Sites in St Louis +32 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06855277·Phase 3·Recruiting·Listed Mar 2025

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ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

for Aortic Regurgitation

Sites in St Louis +28 more locations

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: All ages

Code: NCT06608823·Recruiting·Listed Sep 2024

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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

for Colitis, Ulcerative

Sites in St Louis +17 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 2 - 17

Code: NCT05076175·Phase 2, Phase 3·Recruiting·Listed Oct 2021

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Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

for Major Depressive Disorder

Sites in O'Fallon +19 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18 - 65

Code: NCT05850689·Phase 3·Recruiting·Listed May 2023

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A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

for Myelodysplastic Syndrome

Sites in Kansas City, Lee's Summit +39 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04227847·Phase 1·Recruiting·Listed Jan 2020

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VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

Sites in St Louis, Weldon Spring +54 more locations

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting·Listed Feb 2024

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

Sites in Kansas City +56 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting·Listed Jul 2024

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A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

for Neoplasms

Sites in Kansas City +24 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 39

Code: NCT05999994·Phase 2·Recruiting·Listed Aug 2023

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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

Sites in St Louis, Columbia +51 more locations

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting·Listed Mar 2019

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A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for Endometrial Adenocarcinoma

Sites in Kansas City +41 more locations

Sponsor: Acrivon Therapeutics

Sex: Female·Age: 18+

Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022

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CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

for Type 1 Diabetes Mellitus

Sites in St Louis, Kansas City +30 more locations

Sponsor: COUR Pharmaceutical Development Company, Inc.

Sex: All·Age: 12 - 35

Code: NCT06783309·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for Hypertension

Sites in Kansas City +32 more locations

Sponsor: SoniVie Inc.

Sex: All·Age: 22 - 75

Code: NCT06559891·Recruiting·Listed Aug 2024

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

Sites in Hannibal +24 more locations

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting·Listed Apr 2025

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DALY II USA/ MB-CART2019.1 for DLBCL

for Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Sites in St Louis +27 more locations

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT04792489·Phase 2·Recruiting·Listed Mar 2021

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

Sites in St Louis +33 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting·Listed May 2025

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A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Drug: riliprubart

Sites in St Louis +27 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290128·Phase 3·Recruiting·Listed Mar 2024

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REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

Sites in Kansas City +70 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

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Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

Sites in St Louis, Lee's Summit +42 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting·Listed Sep 2024

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Sites in Liberty +25 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

Sites in St Louis +85 more locations

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05980949·Phase 3·Recruiting·Listed Aug 2023

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Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for Metastatic Breast Cancer

Sites in St Louis, Kansas City +29 more locations

Sponsor: LeonaBio

Sex: All·Age: 18+

Code: NCT05696626·Phase 3·Recruiting·Listed Jan 2023

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Kansas City +25 more locations

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting·Listed Nov 2024

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Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for Relapsing Multiple Sclerosis

Drug: Remibrutinib

Sites in St Louis +39 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 40 - 70

Code: NCT06846281·Phase 3·Recruiting·Listed Feb 2025

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Tracking Results of Ablations to Combat AF Registry Generation 2

for Atrial Fibrillation

Sites in St Louis +25 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: 18+

Code: NCT05111015·Recruiting·Listed Nov 2021

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