Paid Clinical Trials in Missouri

Missouri has 2,059 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,059 clinical trials

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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

for Colitis Ulcerative

9 locations incl. Anaheim

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 75

Code: NCT07463183·Phase 2·Recruiting

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

11 locations incl. Pheonix

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting

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A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

12 locations incl. Phoenix

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting

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Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma

for Multiple Myeloma

Drug: Selinexor

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07200102·Phase 1·Recruiting

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting

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Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device

for Urge Urinary Incontinence

5 locations incl. Homewood

Sponsor: MedtronicNeuro

Sex: All·Age: 18+

Code: NCT07456865·Recruiting

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Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

for HIV Infections

17 locations incl. Beverly Hills

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07473778·Recruiting

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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

25 locations incl. Anniston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351045·Phase 3·Recruiting

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A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

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Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

for Schizophrenia

Drug: GXV813

7 locations incl. Bentonville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07467993·Phase 2·Recruiting

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

12 locations incl. Santa Monica

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting

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Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

for Advanced Renal Cell Carcinoma

4 locations incl. La Jolla

Sponsor: Karie Runcie

Sex: All·Age: 18+

Code: NCT06863311·Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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Long-Term Open-Label Extension Study of Oral Levosimendan

for Pulmonary Hypertension Associated With HFpEF

5 locations incl. Chicago

Sponsor: Tenax Therapeutics, Inc.

Sex: All·Age: All ages

Code: NCT07436689·Phase 3·Enrolling By Invitation

NT-I7 (Efineptakin Alfa), a Long-acting Human IL-7, Post-Axicabtagene Ciloleucel or Post-Lisocabtagene Maraleucel in Subjects With Relapsed/Refractory Large B-cell Lymphoma

for Large B-cell Lymphoma

Drug: Efineptakin alfa

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07052305·Phase 1·Recruiting

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

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A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for ALK-positive NSCLC

7 locations incl. Aurora

Sponsor: TRIANA Biomedicines, Inc.

Sex: All·Age: 18+

Code: NCT07491497·Phase 1, Phase 2·Recruiting

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Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

for Neuromuscular Diseases (NMD)

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT07478172·Recruiting

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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

80 locations incl. Chandler

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting

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A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

for Overweight or Obesity and Elevated Liver Fat

22 locations incl. Chandler

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07441252·Phase 2·Recruiting

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A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma (PDAC)

2 locations incl. St Louis

Sponsor: BicycleTx Limited

Sex: All·Age: 18+

Code: NCT07450859·Phase 2·Recruiting

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Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes

for Obesity

35 locations incl. Mesa

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07458269·Phase 2·Enrolling By Invitation

Impact of Sleep Restriction on Blood Pressure Reactivity

for Sleep

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07489417·Recruiting

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A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

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Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

for Solid Tumors

5 locations incl. Los Angeles

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07374848·Phase 1·Recruiting

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Eating Disorder Chatbot Optimization

for Eating Disorders

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07218302·Phase 2·Not Yet Recruiting

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

for Sleep Architecture

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 60

Code: NCT07385105·Recruiting

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MedCline Investigational Study for the Treatment of Mild OSA With Positional Therapy

for Mild Obstructive Sleep Apnea

1 location in St Louis

Sponsor: Amenity Health, Inc.

Sex: All·Age: 18+

Code: NCT07492420·Recruiting

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Treating Young Children With Attention Deficit Hyperactivity Disorder

for Attention-Deficit/Hyperactivity Disorder (ADHD)

5 locations incl. Palo Alto

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 - 5

Code: NCT07300956·Phase 4·Not Yet Recruiting

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for Advanced Hepatocellular Carcinoma

107 locations incl. Berkeley

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT07166406·Phase 3·Recruiting

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SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

for Epithelioid Hemangioendothelioma (EHE)

6 locations incl. Stanford

Sponsor: Sarcoma Alliance for Research through Collaboration

Sex: All·Age: 18+

Code: NCT07104331·Phase 2·Recruiting

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AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

for Obesity

Drug: NNC0487-0111

22 locations incl. Miramar

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07339423·Phase 3·Recruiting

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A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)

for Obesity

35 locations incl. Anaheim

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07400653·Phase 3·Recruiting

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BXCL501 After Stress to Increase Recovery Success

for Acute Stress Reaction

3 locations incl. Jacksonville

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 65

Code: NCT06943404·Phase 2·Recruiting

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Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital

for Lung Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 20+·Accepts healthy volunteers

Code: NCT07146568·Recruiting

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Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke

for Large Vessel Occlusion

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 99

Code: NCT07404852·Recruiting

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Reduction of Bacterial Seeding in Total Shoulder Arthroplasty

for Joint Arthroplasty

1 location in St Louis

Sponsor: St. Louis University

Sex: Male·Age: 18+

Code: NCT07406893·Recruiting

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A Study to Learn About mRNA Vaccines Against Influenza in Adults

for Healthy Adults

15 locations incl. Mobile

Sponsor: Pfizer

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07431853·Phase 2·Recruiting

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Remote Ischemic Conditioning for PwSCI

for Spinal Cord Injuries

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07488793·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

for Locally Advanced Adrenal Cortical Carcinoma

Drug: Cabozantinib

69 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT06900595·Phase 2·Recruiting

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