CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myelomafor Relapsed/Refractory Multiple Myeloma16 locations incl. BirminghamSponsor: Caribou Biosciences, Inc.Sex: All·Age: 18+Code: NCT05722418·Phase 1·RecruitingApply to this trial
A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myelomafor Relapsed and/or Refractory Multiple Myeloma13 locations incl. BirminghamSponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanySex: All·Age: 18+Code: NCT06153251·Phase 1·RecruitingApply to this trial
A Phase 1 of CTX-8371 in Patients With Advanced Malignanciesfor Non Small Cell Lung Cancer9 locations incl. MargateSponsor: Compass TherapeuticsSex: All·Age: 18+Code: NCT06150664·Phase 1·RecruitingApply to this trial
A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumorsfor Colorectal Neoplasms4 locations incl. SarasotaSponsor: Janssen Research & Development, LLCSex: All·Age: 18+Code: NCT07107230·Phase 1·RecruitingApply to this trial
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumorsfor Advanced Solid TumorsDrug: Ivonescimab6 locations incl. NorwichSponsor: Revolution Medicines, Inc.Sex: All·Age: 18+Code: NCT07397338·Phase 1, Phase 2·RecruitingApply to this trial
IKS014 in Advanced Solid Tumors That Express HER2for Breast Cancer4 locations incl. Newport BeachSponsor: Iksuda Therapeutics Ltd.Sex: All·Age: 18+Code: NCT05872295·Phase 1·RecruitingApply to this trial
A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancersfor Colorectal Cancer3 locations incl. DuarteSponsor: Dispatch BiotherapeuticsSex: All·Age: 18+Code: NCT07544589·Phase 1·RecruitingApply to this trial
Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancerfor Ovarian Cancer5 locations incl. PeoriaSponsor: Nerviano Medical SciencesSex: Female·Age: 18+Code: NCT06930755·Phase 1·RecruitingApply to this trial
A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumorsfor Locally Advanced or Metastatic Malignant Solid Tumors4 locations incl. HackensackSponsor: Astellas Pharma Global Development, Inc.Sex: All·Age: 18+Code: NCT07287995·Phase 1, Phase 2·RecruitingApply to this trial
A Safety and Efficacy Long-Term Follow-up Study of Adult Participants Treated With Gene Modified T Cellsfor Long Term Safety Following GM T Cell Therapy1 location in NashvilleSponsor: Regeneron PharmaceuticalsSex: All·Age: 18+Code: NCT06798298·RecruitingApply to this trial
A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumorsfor Advanced Solid Tumor, Adult6 locations incl. Grand RapidsSponsor: Cogent Biosciences, Inc.Sex: All·Age: 18+Code: NCT07361562·Phase 1·RecruitingApply to this trial
This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphomafor Non-Hodgkin Lymphoma Refractory/ Relapsed5 locations incl. DuarteSponsor: LTZ Therapeutics, Inc.Sex: All·Age: 18+Code: NCT07121946·Phase 1·RecruitingApply to this trial
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignanciesfor Relapsed/Refractory B-cell Malignancies9 locations incl. DenverSponsor: Accutar Biotechnology IncSex: All·Age: 18+Code: NCT05780034·Phase 1·RecruitingApply to this trial
A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumorsfor Advanced Solid Tumors7 locations incl. Los AngelesSponsor: LigaChem Biosciences, Inc.Sex: All·Age: 18+Code: NCT05941507·Phase 1, Phase 2·RecruitingApply to this trial
Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancerfor Breast Cancer8 locations incl. ColumbiaSponsor: SCRI Development Innovations, LLCSex: All·Age: 18+Code: NCT05748834·Phase 2·RecruitingApply to this trial