JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumabfor Acute Respiratory Distress Syndrome (ARDS)Drug: Bevacizumab40 locations incl. BirminghamSponsor: PPD Development, LPSex: All·Age: 18+Code: NCT06701656·Phase 2·RecruitingApply to this trial
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagusfor Esophageal Stricture34 locations incl. BirminghamSponsor: GIE MedicalSex: All·Age: 22+Code: NCT05561114·Phase 3·RecruitingApply to this trial
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowelfor Bowel33 locations incl. ScottsdaleSponsor: GIE MedicalSex: All·Age: 22+Code: NCT05561127·Phase 3·RecruitingApply to this trial
Nectero EAST System Clinical Studyfor Abdominal Aortic Aneurysm37 locations incl. ScottsdaleSponsor: Nectero Medical, Inc.Sex: All·Age: 21 - 85Code: NCT06001918·Phase 2, Phase 3·RecruitingApply to this trial
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Diseasefor Parkinsons Disease (PD)33 locations incl. Sun CitySponsor: BlueRock TherapeuticsSex: All·Age: 45 - 75Code: NCT06944522·Phase 3·RecruitingApply to this trial
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Diseasefor cGVHD32 locations incl. BirminghamSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT05919511·RecruitingApply to this trial
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimabfor Acute Respiratory Distress Syndrome (ARDS)40 locations incl. BirminghamSponsor: PPD Development, LPSex: All·Age: 18+Code: NCT06701682·Phase 2·RecruitingApply to this trial
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubartfor Acute Respiratory Distress Syndrome (ARDS)Drug: Cohort B: paridiprubart40 locations incl. BirminghamSponsor: PPD Development, LPSex: All·Age: 18+Code: NCT06701669·Phase 2·RecruitingApply to this trial
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)for Acute Respiratory Distress Syndrome (ARDS)40 locations incl. BirminghamSponsor: PPD Development, LPSex: All·Age: 18+Code: NCT06703073·Phase 2·RecruitingApply to this trial
SELUTION4BTK Trialfor Peripheral Arterial Disease30 locations incl. ChandlerSponsor: M.A. Med Alliance S.A.Sex: All·Age: 18+Code: NCT05055297·RecruitingApply to this trial
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectivenessfor Aortic Dissection31 locations incl. BirminghamSponsor: Endospan Ltd.Sex: All·Age: 18+Code: NCT04471909·RecruitingApply to this trial
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutationfor Metastatic Colorectal CancerDrug: Bevacizumab26 locations incl. ChandlerSponsor: AmgenSex: All·Age: 18+Code: NCT06252649·Phase 3·RecruitingApply to this trial
DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosisfor Venous Thromboembolism48 locations incl. ScottsdaleSponsor: Inari MedicalSex: All·Age: 18+Code: NCT05701917·RecruitingApply to this trial
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)for Chronic Graft-versus-host-disease47 locations incl. BirminghamSponsor: Syndax PharmaceuticalsSex: All·Age: 2+Code: NCT04710576·Phase 2·RecruitingApply to this trial
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myelomafor Multiple Myeloma41 locations incl. BirminghamSponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanySex: All·Age: 18+Code: NCT06297226·Phase 2·RecruitingApply to this trial
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemiafor AML38 locations incl. GilbertSponsor: Kura Oncology, Inc.Sex: All·Age: 18+Code: NCT06001788·Phase 1·RecruitingApply to this trial
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2for Single Ventricle Heart Disease37 locations incl. PhoenixSponsor: Mezzion Pharma Co. LtdSex: All·Age: 12 - 18Code: NCT05918211·Phase 3·RecruitingApply to this trial
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Proteinfor Alpha1-Antitrypsin Deficiency37 locations incl. BirminghamSponsor: TakedaSex: All·Age: 18 - 75Code: NCT05677971·Phase 3·RecruitingApply to this trial
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemiafor Critical Limb Ischemia30 locations incl. La JollaSponsor: LimFlow, Inc.Sex: All·Age: 18 - 95Code: NCT05313165·RecruitingApply to this trial
J-Valve Transfemoral Pivotal Studyfor Aortic Valve Regurgitation34 locations incl. ScottsdaleSponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLCSex: All·Age: 18+Code: NCT06455787·RecruitingApply to this trial
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunctionfor Lung Transplant Rejection32 locations incl. BirminghamSponsor: SanofiSex: All·Age: 18+Code: NCT06082037·Phase 3·RecruitingApply to this trial
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEMfor Heart Failure37 locations incl. FairhopeSponsor: Cordio MedicalSex: All·Age: 22+Code: NCT06378632·RecruitingApply to this trial
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).for PediatricDrug: Aficamten26 locations incl. PhoenixSponsor: CytokineticsSex: All·Age: 12 - 17Code: NCT06412666·Phase 2, Phase 3·RecruitingApply to this trial
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetesfor Type 1 Diabetes Mellitus32 locations incl. ScottsdaleSponsor: SanofiSex: All·Age: 1 - 25Code: NCT07088068·Phase 3·RecruitingApply to this trial
Registry for Stage 2 Type 1 Diabetesfor Type 1 Diabetes37 locations incl. Los AngelesSponsor: SanofiSex: All·Age: All agesCode: NCT06481904·RecruitingApply to this trial
(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumorsfor Advanced Gastrointestinal Stromal Tumors36 locations incl. BirminghamSponsor: Cogent Biosciences, Inc.Sex: All·Age: 18+Code: NCT05208047·Phase 3·RecruitingApply to this trial
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophyfor Heart FailureDrug: CDR132L29 locations incl. BirminghamSponsor: Novo Nordisk A/SSex: All·Age: 40 - 84Code: NCT06979362·Phase 2·RecruitingApply to this trial
Pan Tumor Rollover Studyfor Cancer59 locations incl. HuntsvilleSponsor: Bristol-Myers SquibbSex: All·Age: 18+Code: NCT03899155·Phase 2·RecruitingApply to this trial
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancerfor Metastatic Breast Cancer18 locations incl. DuarteSponsor: Hoffmann-La RocheSex: All·Age: 18+Code: NCT03424005·Phase 1, Phase 2·RecruitingApply to this trial
A Study of ASP3082 in Adults With Advanced Solid Tumorsfor Solid Tumor25 locations incl. DuarteSponsor: Astellas Pharma IncSex: All·Age: 18+Code: NCT05382559·Phase 1·RecruitingApply to this trial
A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injuryfor Traumatic Brain Injury13 locations incl. SacramentoSponsor: Hoffmann-La RocheSex: All·Age: 18+Code: NCT07455136·RecruitingApply to this trial
Onyx™ Liquid Embolic IDE Clinical Studyfor Peripheral Arterial Hemorrhage18 locations incl. PhoenixSponsor: Medtronic EndovascularSex: All·Age: 22+Code: NCT06742801·RecruitingApply to this trial
Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.for Hematuria - Cause Not Known20 locations incl. HomewoodSponsor: Pacific Edge LimitedSex: All·Age: 18 - 88Code: NCT06394869·RecruitingApply to this trial
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusionsfor Myelodysplastic Syndromes23 locations incl. DuarteSponsor: TakedaSex: All·Age: 18+Code: NCT06499285·Phase 3·RecruitingApply to this trial
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)for Amyloid Plaque13 locations incl. PhoenixSponsor: AC Immune SASex: All·Age: 35 - 85Code: NCT05462106·Phase 1, Phase 2·RecruitingApply to this trial
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)for Progressive Pulmonary Fibrosis25 locations incl. BirminghamSponsor: Avalyn Pharma Inc.Sex: All·Age: 18+Code: NCT06951217·Phase 2·RecruitingApply to this trial
A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatmentfor Noonan SyndromeDrug: Vosoritide22 locations incl. Los AngelesSponsor: BioMarin PharmaceuticalSex: All·Age: 3 - 11Code: NCT06668805·Phase 2·RecruitingApply to this trial
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancersfor Lymphoma, Non-Hodgkin'sDrug: LY458418021 locations incl. ScottsdaleSponsor: Eli Lilly and CompanySex: All·Age: 18+Code: NCT07226843·Phase 1·RecruitingApply to this trial
Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriersfor Huntington Disease13 locations incl. BirminghamSponsor: Hoffmann-La RocheSex: All·Age: 25 - 60Code: NCT06667414·RecruitingApply to this trial
VTP-1000 in Adults With Celiac Diseasefor Celiac Disease16 locations incl. Los AngelesSponsor: Barinthus BiotherapeuticsSex: All·Age: 18 - 70Code: NCT06310291·EARLY_Phase 1·RecruitingApply to this trial