Clinical Trials at Vanderbilt University Medical Center

As of September 2026, 318 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at 1215 21ST AVE S, SUITE 9302, NASHVILLE, TN 37232-0014, phone (615) 343-6152 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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320 clinical trials at Vanderbilt University Medical Center

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Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

Sites in Nashville +20 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting·Listed Jul 2025

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Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

for Delirium

Sites in Nashville +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06192615·Phase 3·Recruiting·Listed Jan 2024

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Impact of Sinus Surgery on Individuals With Cystic Fibrosis

for Chronic Rhinosinusitis (Diagnosis)

Sites in Nashville +8 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 99

Code: NCT04469439·Recruiting·Listed Jul 2020

Apply to this trial

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

Sites in Nashville +23 more locations

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting·Listed Mar 2025

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

Sites in Nashville, Memphis +18 more locations

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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Digoxin Medulloblastoma Study

for Medulloblastoma

Sites in Nashville +16 more locations

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 12 Months - 30

Code: NCT06701812·Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

Sites in Nashville, Memphis +31 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting·Listed Jun 2023

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Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

Sites in Nashville +14 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting·Listed Jun 2022

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

Sites in Nashville +5 more locations

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting·Listed Nov 2025

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

for Post Operative Surgical Site Infection

Sites in Nashville +30 more locations

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting·Listed Dec 2020

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Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy

for Duchenne Muscular Dystrophy (DMD)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Male·Age: 8 - 18

Code: NCT07172971·Phase 1·Recruiting·Listed Sep 2025

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The Dose Trial: Dose Intensity of Behavioral Interventions for Childhood Obesity

for Childhood Obesity

Sites in Nashville +1 more location

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 5 - 17

Code: NCT06654323·Recruiting·Listed Oct 2024

Apply to this trial

Respiratory Strength Training in Heart Transplant Recipients

for Dysphagia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 90

Code: NCT06190171·Recruiting·Listed Jan 2024

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Nashville +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

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Accelerated Flap Coverage in Severe Lower Extremity Trauma

for Open Tibia Fracture

Sites in Nashville +6 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06293469·Recruiting·Listed Mar 2024

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Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

for Tremor

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT01734122·Recruiting·Listed Nov 2012

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Alzheimer's Tau Platform: Master Protocol

for Preclinical Alzheimer's Disease

Sites in Nashville +2 more locations

Sponsor: Paul S. Aisen

Sex: All·Age: 50 - 80

Code: NCT06957418·Phase 2·Recruiting·Listed May 2025

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VoiceLove: An App-Based COMMunication Tool Designed to Address DeliriUm and Improve Family ENgagement and PatIent/Family SatisfaCtion in CriticAlly Ill PaTiEnts (COMMUNICATE)

for Critical Illness

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06923462·Recruiting·Listed Apr 2025

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The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

Sites in Nashville +12 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting·Listed Mar 2025

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Tranexamic Acid in Nasal Mohs Reconstruction

for Postoperative Bleeding

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06057675·Phase 2·Recruiting·Listed Sep 2023

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Subcortical Arousal in Perceptual Awareness

for Epilepsy

Sites in Nashville +7 more locations

Sponsor: Yale University

Sex: All·Age: 13+

Code: NCT06934356·Recruiting·Listed Apr 2025

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An International Observational Study of Adults With Acute Infection

for Infectious Disease

Sites in Nashville +19 more locations

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07069400·Recruiting·Listed Jul 2025

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Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions

for Valvular Heart Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06077201·Recruiting·Listed Oct 2023

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

Sites in Nashville +17 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting·Listed May 2024

Apply to this trial

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

for Microtia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 89

Code: NCT05288790·Phase 2·Recruiting·Listed Mar 2022

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Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Drug: Tirzepatide

Sites in Nashville +8 more locations

Sponsor: T. John Winhusen, PhD

Sex: All·Age: 18+

Code: NCT06651177·Phase 2·Recruiting·Listed Oct 2024

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DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

Sites in Nashville +24 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting·Listed Oct 2023

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The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study

for Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05464095·Recruiting·Listed Jul 2022

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Nashville, Memphis +74 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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Primary Subtalar Arthrodesis for Calcaneal Fractures

for Calcaneus Fracture

Sites in Nashville +16 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06249126·Recruiting·Listed Feb 2024

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Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage

for End Stage Chronic Renal Failure

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07385651·Recruiting·Listed Feb 2026

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Nashville +35 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

Apply to this trial

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

for Familial Hypercholesterolemia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 69

Code: NCT04941599·Phase 2·Recruiting·Listed Jun 2021

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SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

for Endothelial Dysfunction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05812755·Phase 4·Recruiting·Listed Apr 2023

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Point-of-Care Ophthalmic Diagnostic Imaging of Retinopathy of Prematurity

for Retinopathy of Prematurity (ROP)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 24 Weeks - 34 Weeks

Code: NCT06612541·Recruiting·Listed Sep 2024

Apply to this trial

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

Sites in Nashville +32 more locations

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting·Listed Sep 2023

Apply to this trial

Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

Sites in Nashville +23 more locations

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting·Listed Jan 2024

Apply to this trial

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

Sites in Nashville +5 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting·Listed May 2024

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Cooperative Assessment of Late Effects for SCD Curative Therapies

for Sickle Cell Disease

Sites in Nashville +4 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 4 - 65

Code: NCT05153967·Recruiting·Listed Dec 2021

Apply to this trial

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

for HNSCC

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06819228·Phase 1·Recruiting·Listed Feb 2025

Apply to this trial