Primary Subtalar Arthrodesis for Calcaneal Fracturesfor Calcaneus Fracture17 locations incl. OrangeSponsor: Wake Forest University Health SciencesSex: All·Age: 18+Code: NCT06249126·RecruitingApply to this trial
PREcision MEDicine In Achalasia (PREMEDIA) - Cohortfor Type III Achalasia13 locations incl. ScottsdaleSponsor: Northwestern UniversitySex: All·Age: 18+Code: NCT07293689·RecruitingApply to this trial
PREcision MEDicine In Achalasia (PREMEDIA)for Type I Achalasia13 locations incl. ScottsdaleSponsor: Northwestern UniversitySex: All·Age: 18+Code: NCT07293650·Phase 3·RecruitingApply to this trial
Single Versus Dual Implant Fixation of Distal Femur Fracturesfor Articular Fractures16 locations incl. BirminghamSponsor: Wake Forest University Health SciencesSex: All·Age: 18+Code: NCT06286670·RecruitingApply to this trial
Pulmonary Hypertension Association Registryfor Pulmonary Arterial Hypertension52 locations incl. PhoenixSponsor: Pulmonary Hypertension Association, Inc.Sex: All·Age: 0+Code: NCT04071327·RecruitingApply to this trial
Increasing Germline Genetic Testing for Patients With Cancerfor Hereditary Pancreatic Cancer10 locations incl. Los AngelesSponsor: Josh PetersonSex: All·Age: All ages·Accepts healthy volunteersCode: NCT07307664·RecruitingApply to this trial
Digoxin Medulloblastoma Studyfor Medulloblastoma15 locations incl. BirminghamSponsor: H. Lee Moffitt Cancer Center and Research InstituteSex: All·Age: 12 Months - 30Code: NCT06701812·Phase 2·RecruitingApply to this trial
Rehabilitation With Empowered STrategies to Optimize REcoveryfor Lumbar Spine Degenerative Changes4 locations incl. HonoluluSponsor: Vanderbilt University Medical CenterSex: All·Age: 18 - 85Code: NCT07406997·RecruitingApply to this trial
Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trialfor Osteomyelitis Tibia14 locations incl. GainesvilleSponsor: Wake Forest University Health SciencesSex: All·Age: 18+Code: NCT05421741·Phase 4·RecruitingApply to this trial
Lupus Landmark Study: A Prospective Registry and Biorepositoryfor Systemic Lupus Erythematosus (SLE)19 locations incl. BirminghamSponsor: Lupus Research AllianceSex: All·Age: 18 - 110Code: NCT05934149·RecruitingApply to this trial
Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trialsfor Duchenne Muscular Dystrophy (DMD)9 locations incl. SacramentoSponsor: Vanderbilt University Medical CenterSex: All·Age: All agesCode: NCT07674758·Recruiting·Listed Jun 30, 2026Apply to this trial
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPDfor Chronic Obstructive Pulmonary Disease (COPD)Drug: Omalizumab23 locations incl. BirminghamSponsor: Johns Hopkins UniversitySex: All·Age: 40+Code: NCT07059091·Phase 2·RecruitingApply to this trial
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetesfor Type2Diabetes36 locations incl. HuntsvilleSponsor: Brigham and Women's HospitalSex: All·Age: 40 - 80Code: NCT05390892·Phase 4·RecruitingApply to this trial
Platform Clinical Study for Conquering Sclerodermafor Interstitial Lung Disease Due to Systemic Disease34 locations incl. BirminghamSponsor: Scleroderma Research Foundation, Inc.Sex: All·Age: 18+Code: NCT06195072·Phase 2·RecruitingApply to this trial
American Lung Association (ALA) Lung Health Cohortfor Lung Diseases37 locations incl. BirminghamSponsor: Johns Hopkins UniversitySex: All·Age: 25 - 35·Accepts healthy volunteersCode: NCT04543461·RecruitingApply to this trial
ATrial Tachycardia PAcing Therapy in Congenital Heartfor Atrial Arrhythmia14 locations incl. Los AngelesSponsor: Ian LawSex: All·Age: All agesCode: NCT03209583·RecruitingApply to this trial
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Studyfor Ischemic Heart Disease (IHD)12 locations incl. San FranciscoSponsor: Brigham and Women's HospitalSex: All·Age: 35 - 85Code: NCT06854458·RecruitingApply to this trial
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)for Delirium14 locations incl. Los AngelesSponsor: Massachusetts General HospitalSex: All·Age: 60+Code: NCT06192615·Phase 3·RecruitingApply to this trial
OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Agesfor Eosinophilic Gastrointestinal Disorders (EGIDs)19 locations incl. PhoenixSponsor: Children's Hospital Medical Center, CincinnatiSex: All·Age: 3+Code: NCT02523118·RecruitingApply to this trial
RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturEfor Osteoporosis23 locations incl. BirminghamSponsor: University of Alabama at BirminghamSex: All·Age: 50+Code: NCT06455085·RecruitingApply to this trial
The APS Phenotyping Studyfor ARDS20 locations incl. FresnoSponsor: Vanderbilt University Medical CenterSex: All·Age: 18+Code: NCT06521502·RecruitingApply to this trial
DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatmentfor Ductal Carcinoma in Situ28 locations incl. BerkeleySponsor: QuantumLeap Healthcare CollaborativeSex: Female·Age: 18+Code: NCT06075953·Phase 2·RecruitingApply to this trial
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Diseasefor Huntington's Disease6 locations incl. EnglewoodSponsor: University College, LondonSex: All·Age: 11 - 75·Accepts healthy volunteersCode: NCT02855476·RecruitingApply to this trial
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)for AVB - Atrioventricular Block23 locations incl. PhoenixSponsor: NYU Langone HealthSex: Female·Age: 18+Code: NCT04474223·Phase 3·RecruitingApply to this trial
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disordersfor Hematologic Disorder71 locations incl. PhoenixSponsor: American Thrombosis and Hemostasis NetworkSex: All·Age: All agesCode: NCT04398628·RecruitingApply to this trial
Platform of Randomized Adaptive Clinical Trials in Critical Illnessfor Respiratory Insufficiency26 locations incl. TucsonSponsor: University Health Network, TorontoSex: All·Age: 18+Code: NCT05440851·RecruitingApply to this trial
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)for Coronary Artery Disease17 locations incl. PhoenixSponsor: Emory UniversitySex: All·Age: 18+Code: NCT07559903·RecruitingApply to this trial
Neurophysiologic Biomarkers in Rett Syndromefor Rett Syndrome6 locations incl. Los AngelesSponsor: Children's Hospital of PhiladelphiaSex: Female·Age: 1 - 18·Accepts healthy volunteersCode: NCT05932589·RecruitingApply to this trial
The HOPE Biobank Resource (BMT CTN 2402 HOPE)for Aplastic Anemias6 locations incl. GainesvilleSponsor: Medical College of WisconsinSex: All·Age: All ages·Accepts healthy volunteersCode: NCT07227155·RecruitingApply to this trial
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorderfor Opioid Use DisorderDrug: Tirzepatide9 locations incl. JacksonvilleSponsor: T. John Winhusen, PhDSex: All·Age: 18+Code: NCT06651177·Phase 2·RecruitingApply to this trial
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEsfor Liver Diseases18 locations incl. Los AngelesSponsor: European Foundation for Study of Chronic Liver FailureSex: All·Age: 18 - 80Code: NCT04613921·RecruitingApply to this trial
Subcortical Arousal in Perceptual Awarenessfor Epilepsy8 locations incl. New HavenSponsor: Yale UniversitySex: All·Age: 13+Code: NCT06934356·RecruitingApply to this trial
Impact of Sinus Surgery on Individuals With Cystic Fibrosisfor Chronic Rhinosinusitis (Diagnosis)9 locations incl. Los AngelesSponsor: University of California, Los AngelesSex: All·Age: 18 - 99Code: NCT04469439·RecruitingApply to this trial
A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)for Renal Cell Carcinoma, Clear CellDrug: Ipilimumab6 locations incl. BostonSponsor: M.D. Anderson Cancer CenterSex: All·Age: 18+Code: NCT06708949·Phase 2·RecruitingApply to this trial
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registryfor Pulmonary Vascular Disease13 locations incl. Palo AltoSponsor: New York Medical CollegeSex: All·Age: 1 Day - 21Code: NCT02249923·RecruitingApply to this trial
Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Childrenfor Hemorrhagic Shock23 locations incl. TucsonSponsor: Philip SpinellaSex: All·Age: Up to 17Code: NCT06070350·Phase 3·RecruitingApply to this trial
Gluten Technology and Education for Celiac Healthfor Celiac Disease4 locations incl. ChicagoSponsor: Columbia UniversitySex: All·Age: 18 - 75Code: NCT06059716·RecruitingApply to this trial
The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Lifefor Systemic Sclerosis (SSc)4 locations incl. New OrleansSponsor: Robyn T. Domsic, MD, MPHSex: All·Age: 18+Code: NCT06675344·RecruitingApply to this trial
Treatment With Endovascular Intervention for STroke Patients With Existing Disabilityfor Stroke25 locations incl. PhoenixSponsor: University of CincinnatiSex: All·Age: 18+Code: NCT05911568·RecruitingApply to this trial
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKDfor Chronic Kidney Diseases2 locations incl. SacramentoSponsor: University of California, DavisSex: All·Age: 21 - 85Code: NCT04984226·Phase 2·RecruitingApply to this trial