Paid Clinical Trials in North Carolina

North Carolina has 2,939 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,939 clinical trials

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A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

15 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for Ovarian Cancer

23 locations incl. La Jolla

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07059845·Phase 2·Recruiting

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

12 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

for Cardiovascular Disease Acute

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07159269·Recruiting

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A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT07223138·Phase 3·Enrolling By Invitation

A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

for Hidradenitis Suppurativa

Drug: Ritlecitinib

32 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18 - 75

Code: NCT07228390·Phase 2·Recruiting

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HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

for Hematologic Malignancy

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06731504·EARLY_Phase 1·Recruiting

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Virtual Village for Young Parents

for Gender-based Violence

1 location in Durham

Sponsor: RTI International

Sex: All·Age: 16 - 21·Accepts healthy volunteers

Code: NCT07226401·Recruiting

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Impact of Anatomy-Based Cochlear Implant Programming on Early Performance

for Hearing Loss, Unilateral

6 locations incl. Iowa City

Sponsor: Med-El Corporation

Sex: All·Age: 18+

Code: NCT06734039·Enrolling By Invitation

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

for Pulmonary Hypertension

13 locations incl. Sacramento

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07073820·Phase 2·Recruiting

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A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

10 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 6 Months - 6

Code: NCT07112378·Phase 3·Recruiting

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A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

for Hypothalamic Obesity

6 locations incl. Aurora

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07156578·Phase 2·Enrolling By Invitation

Pediatrics Mobile CT

for Pediatric Abdominal Imaging

1 location in Durham

Sponsor: Duke University

Sex: All·Age: Up to 5

Code: NCT07166926·Recruiting

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

6 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting

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A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

for Atrial Fibrillation (AF)

32 locations incl. Birmingham

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07187115·Recruiting

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Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

for Osteoarthritis Knee Pain

20 locations incl. San Diego

Sponsor: Saol Therapeutics Inc

Sex: All·Age: 40+

Code: NCT07226258·Phase 3·Recruiting

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

148 locations incl. Loma Linda

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting

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Comparison of Urinary Flow Study

for Urinary Retention

1 location in Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18+

Code: NCT06918067·Recruiting

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A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

for Bronchiectasis With Pseudomonas Aeruginosa Colonization

25 locations incl. Orange

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07088926·Phase 2·Recruiting

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A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

for Non-muscle Invasive Bladder Cancer

39 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07206225·Phase 1·Recruiting

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A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

for Moderate to Severe Plaque Psoriasis

Drug: Bimekizumab

4 locations incl. Santa Monica

Sponsor: UCB Biopharma SRL

Sex: Female·Age: 18+

Code: NCT06888193·Phase 1·Recruiting

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Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain

for Pain, Acute

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07053774·Phase 2·Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

261 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

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Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

for Tobacco Use

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 21 - 65

Code: NCT06983678·Recruiting

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Timing of Physician Rounds for Antepartum Patients

for Physician Rounds

2 locations incl. Durham

Sponsor: Duke University

Sex: Female·Age: 18+

Code: NCT07215507·Recruiting

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A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart

21 locations incl. Little Rock

Sponsor: Vasa Therapeutics

Sex: All·Age: 50+

Code: NCT07219511·Phase 1·Recruiting

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Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging

for Breast Cancer

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225114·Phase 2·Recruiting

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

6 locations incl. Tampa

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting

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Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).

for Dry Eye Disease

10 locations incl. Glendale

Sponsor: Instituto Grifols, S.A.

Sex: All·Age: 18+

Code: NCT07264517·Phase 2·Recruiting

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Immersive Physical Therapy in the Neonatal Intensive Care Unit (NICU)

for Physical Therapy

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 0 - 99

Code: NCT06927037·Recruiting

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COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

for Ulcerative Colitis, Pediatric

4 locations incl. Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 1 - 18

Code: NCT07198113·Recruiting

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Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.

for Infertility (IVF Patients)

16 locations incl. Encino

Sponsor: Granata Bio Corporation

Sex: Female·Age: 18 - 42

Code: NCT07216742·Phase 3·Recruiting

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Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

for Complex Aneuploidy

11 locations incl. Margate

Sponsor: Shady Grove Fertility Reproductive Science Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07227116·Recruiting

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I-DECIDE After Bronchiolitis Hospitalization

for Bronchiolitis Acute

56 locations incl. Birmingham

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Months - 24 Months

Code: NCT07243652·Recruiting

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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

20 locations incl. San Jose

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting

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An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

for Dry Eye

5 locations incl. Newport Beach

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07179055·Phase 2·Recruiting

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A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

for Eosinophilic Esophagitis

41 locations incl. Little Rock

Sponsor: Phathom Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06851559·Phase 2·Recruiting

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Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

for Pompe Disease

9 locations incl. Irvine

Sponsor: Shionogi

Sex: All·Age: 18+

Code: NCT07123155·Phase 2·Recruiting

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Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD

for Chronic Graft Versus Host Disease

Drug: Fostamatinib

1 location in Durham

Sponsor: Stefanie Sarantopoulos, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT06233110·Phase 1·Recruiting

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Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for Geographic Atrophy (GA)

27 locations incl. Gilbert

Sponsor: ONL Therapeutics

Sex: All·Age: 55+

Code: NCT06659445·Phase 2·Recruiting

Apply to this trial