Oncology Clinical Trials in New Haven, CT

As of June 2026, 233 paid clinical trials are recruiting for Oncology in New Haven, Connecticut. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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233 clinical trials for Oncology

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

133 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting

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A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

13 locations incl. Duarte

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06172478·Phase 2·Recruiting

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SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. New Haven

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting

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Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for AML

38 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06001788·Phase 1·Recruiting

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A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

for Ovarian Cancer

14 locations incl. Denver

Sponsor: OnCusp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06234423·Phase 1·Recruiting

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QTX3034 in Patients With KRAS G12D Mutation

for Solid Tumors

14 locations incl. Los Angeles

Sponsor: Quanta Therapeutics

Sex: All·Age: 18+

Code: NCT06227377·Phase 1·Recruiting

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

for Multiple Myeloma

Drug: Talquetamab

49 locations incl. Clovis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06208150·Phase 3·Recruiting

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FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

for Advanced Solid Tumor

14 locations incl. Gilbert

Sponsor: Fate Therapeutics

Sex: All·Age: 18+

Code: NCT06241456·Phase 1·Recruiting

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Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT04974671·Phase 2·Recruiting

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Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

for Melanoma

3 locations incl. New Haven

Sponsor: IO Biotech

Sex: All·Age: 18+

Code: NCT05280314·Phase 2·Recruiting

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A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

89 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06119581·Phase 3·Recruiting

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Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC

for Metastatic Castration-resistant Prostate Cancer

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06100705·Phase 2·Recruiting

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A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

23 locations incl. Tucson

Sponsor: Eikon Therapeutics

Sex: All·Age: 18 - 89

Code: NCT06253130·Phase 1, Phase 2·Recruiting

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A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas

for Advanced Solid Tumors

4 locations incl. San Francisco

Sponsor: Antengene Biologics Limited

Sex: All·Age: 18+

Code: NCT06028373·Phase 1·Recruiting

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Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

for Breast Cancer

79 locations incl. Phoenix

Sponsor: BriaCell Therapeutics Corporation

Sex: All·Age: 18+

Code: NCT06072612·Phase 3·Recruiting

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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

16 locations incl. Davis

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

for Breast Cancer

Drug: Durvalumab

64 locations incl. Daphne

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06103864·Phase 3·Recruiting

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A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

for Hematologic Malignancy

17 locations incl. Duarte

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT06208878·Enrolling By Invitation

Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors

for Solid Tumor

4 locations incl. Scottsdale

Sponsor: Qualigen Theraputics, Inc.

Sex: All·Age: 18+

Code: NCT06086522·Phase 1·Recruiting

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

76 locations incl. Phoenix

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT05899608·Phase 3·Recruiting

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A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for Lymphoma

Drug: Glofitamab

18 locations incl. Berkeley

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06084936·Phase 3·Recruiting

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Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

237 locations incl. Little Rock

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 60+

Code: NCT05976763·Phase 3·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1204 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for Advanced Solid Tumor

14 locations incl. Los Angeles

Sponsor: Volastra Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05902988·Phase 1, Phase 2·Recruiting

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Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

for Advanced Malignant Solid Neoplasm

23 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05691491·Phase 1, Phase 2·Recruiting

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A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Duarte

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05981703·Phase 1·Recruiting

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Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for Non-small Cell Lung Cancer (NSCLC)

17 locations incl. Sacramento

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06040541·Phase 1·Recruiting

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Study of AVZO-021 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. New Haven

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05867251·Phase 1, Phase 2·Recruiting

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

24 locations incl. Beverly Hills

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting

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Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

for Breast Cancer

7 locations incl. New Haven

Sponsor: Carevive Systems, Inc.

Sex: All·Age: 18+

Code: NCT05974150·Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

44 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting

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A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation

for Non-Small Cell Lung Cancer

Drug: Divarasib

16 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT05789082·Phase 1, Phase 2·Recruiting

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Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

36 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting

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SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

31 locations incl. Birmingham

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting

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A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical Cancer

for Cervical Cancer

2 locations incl. New Haven

Sponsor: Yale University

Sex: Female·Age: 18+

Code: NCT05838521·Phase 2·Recruiting

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FOG-001 in Locally Advanced or Metastatic Solid Tumors

for Cancer

31 locations incl. Phoenix

Sponsor: Parabilis Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05919264·Phase 1, Phase 2·Recruiting

Apply to this trial

XTX301 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. Sacramento

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT05684965·Phase 1, Phase 2·Recruiting

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A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

for Advanced Prostate Cancer

5 locations incl. Scottsdale

Sponsor: Genentech, Inc.

Sex: Male·Age: 18+

Code: NCT05800665·Phase 1·Recruiting

Apply to this trial

Exercise in Metastatic Breast Cancer: EMBody

for Breast Cancer

6 locations incl. New Haven

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05468034·Recruiting

Apply to this trial

Trial of Exercise and Lifestyle for Women With Ovarian and Endometrial Cancer

for Ovarian Cancer

2 locations incl. New Haven

Sponsor: Yale University

Sex: Female·Age: 18+

Code: NCT05761561·Recruiting

Apply to this trial

Conditions in Oncology (New Haven, CT)

Solid tumor· 60 Non-small cell lung cancer (NSCLC)· 31 Breast cancer· 29 Cancer (any)· 16 Prostate cancer· 13 Ovarian cancer· 13 Acute myeloid leukemia (AML)· 13 Metastatic breast cancer· 12 Head and neck cancer· 12 Gastric cancer· 10 Endometrial cancer· 10 Colorectal cancer· 9 Multiple myeloma· 9 Hematologic malignancy· 9 Esophageal cancer· 8 Myelodysplastic syndromes (MDS)· 8 Metastatic prostate cancer· 7 Pancreatic cancer· 6 Melanoma· 6 HER2-negative breast cancer· 5 Lung cancer· 5 Cervical cancer· 5 Glioma· 5 Leukemia (other)· 5 Non-Hodgkin lymphoma· 5 Triple-negative breast cancer· 4 Gastroesophageal junction cancer· 4 Biliary tract cancer· 4 Bladder cancer· 4 Fallopian tube cancer· 4 Diffuse large B-cell lymphoma (DLBCL)· 4 HER2-positive breast cancer· 3 Small cell lung cancer· 3 Metastatic colorectal cancer· 3 Kidney cancer· 3 Neuroblastoma· 3 Chronic lymphocytic leukemia (CLL)· 2 Chronic myelomonocytic leukemia· 2 Mantle cell lymphoma· 2 Osteosarcoma· 2 Neuroendocrine tumors· 2 Liver cancer· 1 Gastrointestinal cancer· 1 Glioblastoma· 1 Brain cancer· 1 Acute lymphoblastic leukemia· 1 Myelofibrosis· 1 Myeloproliferative neoplasm· 1 Hodgkin lymphoma· 1 Follicular lymphoma· 1 Marginal zone lymphoma· 1 Small lymphocytic lymphoma· 1 Burkitt lymphoma· 1 Ewing sarcoma· 1