Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
for Stress Urinary Incontinence
Sites in New Haven +3 more locations
Sponsor: Ethicon, Inc.
Sex: Female·Age: 21+
Code: NCT04829175·Recruiting·Listed Apr 2021
Clinical Trials at Yale University
As of August 2026, 228 paid clinical trials are recruiting at Yale University, located at 310 CEDAR ST, 416A LAUDER HALL, NEW HAVEN, CT 06510-3218, phone (203) 785-6843 in New Haven, Connecticut. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
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229 clinical trials at Yale University
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Pharmacokinetics, Efficacy, and Safety of Encaleret in Pediatric Participants With Autosomal Dominant Hypocalcemia Type 1 (ADH1)
for Autosomal Dominant Hypocalcemia Type 1 (ADH1)
Sites in New Haven +3 more locations
Sponsor: Calcilytix Therapeutics, Inc., a BridgeBio company
Sex: All·Age: 0 - 17
Code: NCT07080385·Phase 2, Phase 3·Recruiting·Listed Jul 2025
A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer
for Colorectal Cancer
Sites in New Haven +8 more locations
Sponsor: Criterium, Inc.
Sex: All·Age: 18+
Code: NCT06992258·Phase 2·Recruiting·Listed May 2025
Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors
for Malignant Neoplasm of Breast
Sites in New Haven +4 more locations
Sponsor: Novian Health Inc.
Sex: Female·Age: 18+
Code: NCT03463954·Recruiting·Listed Mar 2018
Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974
for Post-Traumatic Stress Disorder, PTSD
1 location in New Haven
Sponsor: Yale University
Sex: All·Age: 18 - 70·Accepts healthy volunteers
Code: NCT07488819·Recruiting·Listed Mar 2026
Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life
for Diabetes Type 2
1 location in New Haven
Sponsor: Yale University
Sex: All·Age: 40+·Accepts healthy volunteers
Code: NCT07376655·Recruiting·Listed Jan 2026
Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma
for Sinonasal Squamous Cell Carcinoma
Drug: Cemiplimab
Sites in New Haven, Trumbull +11 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07281417·Phase 2·Recruiting·Listed Dec 2025
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in New Haven, West Haven +628 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in New Haven, North Haven +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer
for Astrocytoma, IDH-Mutant, Grade 3
Drug: Vorasidenib
Sites in New Haven, Trumbull +95 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 12+
Code: NCT07215910·Phase 3·Recruiting·Listed Oct 2025
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in New Haven, Orange +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in New Haven, North Haven +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
Sites in New Haven, North Haven +461 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
Sites in New Haven, Trumbull +444 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
Sites in New Haven, Orange +303 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in New Haven, North Haven +591 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in New Haven, Orange +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
for Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Drug: Bevacizumab
Sites in New Haven, North Haven +325 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04181060·Phase 3·Recruiting·Listed Nov 2019
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
for Advanced Hepatocellular Carcinoma
Sites in New Haven, Hamden +136 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT07166406·Phase 3·Recruiting·Listed Sep 2025
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
for Fallopian Tube Endometrioid Adenocarcinoma
Drug: Bevacizumab
Sites in New Haven, Trumbull +653 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in New Haven, North Haven +531 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
for Adenocarcinoma of the Colon
Sites in New Haven, West Haven +325 more locations
Sponsor: NRG Oncology
Sex: All·Age: 45 - 70
Code: NCT05080673·Recruiting·Listed Oct 2021
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in New Haven, Hartford +380 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in New Haven, Hamden +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
for B Acute Lymphoblastic Leukemia
Sites in New Haven +154 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18 - 39
Code: NCT03150693·Phase 3·Recruiting·Listed May 2017
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in New Haven, North Haven +442 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Sites in New Haven, Hamden +324 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06958328·Phase 3·Recruiting·Listed May 2025
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in New Haven, Guilford +406 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
for Ovarian Carcinoma
Sites in New Haven, New Britain +479 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 35 - 50
Code: NCT04251052·Recruiting·Listed Jan 2020
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in New Haven, North Haven +336 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
for Acute Myeloid Leukemia
Sites in New Haven, West Haven +328 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
for Refractory Differentiated Thyroid Gland Carcinoma
Sites in New Haven, North Haven +284 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT06475989·Phase 3·Recruiting·Listed Jun 2024
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
for Mantle Cell Lymphoma
Sites in New Haven, North Haven +228 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 60+
Code: NCT05976763·Phase 3·Recruiting·Listed Aug 2023
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in New Haven, North Haven +378 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Sites in New Haven +205 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT05554406·Phase 2·Recruiting·Listed Sep 2022
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in New Haven, West Haven +214 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06317649·Phase 2·Recruiting·Listed Mar 2024
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in New Haven +168 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT05554393·Phase 2·Recruiting·Listed Sep 2022
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
for Metastatic Dedifferentiated Liposarcoma
Sites in New Haven, Guilford +235 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06422806·Phase 3·Recruiting·Listed May 2024
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
for B Acute Lymphoblastic Leukemia
Sites in New Haven, Hartford +185 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 365 Days - 25
Code: NCT03959085·Phase 3·Recruiting·Listed May 2019
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
for Plasma Cell Myeloma
Sites in New Haven, North Haven +387 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: All ages
Code: NCT05561387·Phase 3·Recruiting·Listed Sep 2022