Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for Atopic Dermatitis

Drug: Upadacitinib

Sites in Philadelphia, Pittsburgh +64 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 63

Code: NCT06389136·Phase 3·Recruiting·Listed Apr 2024

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Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

for Diabetic Foot Ulcer

Sites in McKeesport +25 more locations

Sponsor: Piomic Medical

Sex: All·Age: 22 - 90

Code: NCT05758545·Recruiting·Listed Mar 2023

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EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for Breast Cancer

Sites in Pittsburgh, Hershey +51 more locations

Sponsor: Exact Sciences Corporation

Sex: All·Age: 18+

Code: NCT06401421·Recruiting·Listed May 2024

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Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

for Alopecia Areata

Sites in Plymouth Meeting +53 more locations

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 12 - 17

Code: NCT07133308·Phase 3·Recruiting·Listed Aug 2025

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Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

for GEP-NET

Sites in Pittsburgh +12 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT05477576·Phase 3·Recruiting·Listed Jul 2022

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

Sites in Philadelphia, Pittsburgh +29 more locations

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

Sites in Pittsburgh +25 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting·Listed Oct 2024

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Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

for Lupus Nephritis

Sites in Philadelphia +13 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05268289·Phase 2·Recruiting·Listed Mar 2022

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Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

for Arterial Disease of Legs

Sites in Philadelphia, Bryn Mawr +27 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 21+

Code: NCT06182397·Recruiting·Listed Dec 2023

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

Sites in Pittsburgh, Wynnewood +48 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting·Listed May 2021

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

Sites in Pittsburgh +36 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting·Listed Jun 2023

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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

Sites in Philadelphia +36 more locations

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting·Listed Mar 2025

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

Sites in Philadelphia +31 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting·Listed Dec 2019

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Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

for Atopic Dermatitis

Drug: Nemolizumab

Sites in Philadelphia +57 more locations

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT06988605·Recruiting·Listed May 2025

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FORWARD CAD IDE Study

for Coronary Arterial Disease (CAD)

Sites in York +27 more locations

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT06662500·Recruiting·Listed Oct 2024

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A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

for Chronic Graft-versus-host-disease

Sites in Pittsburgh +12 more locations

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 2+

Code: NCT04710576·Phase 2·Recruiting·Listed Jan 2021

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

Sites in Philadelphia, Doylestown +24 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting·Listed Nov 2024

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Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Sites in Lancaster, Bala-Cynwyd +28 more locations

Sponsor: Dendreon

Sex: Male·Age: 18+

Code: NCT06134232·Phase 2·Recruiting·Listed Nov 2023

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

Sites in Philadelphia, York +25 more locations

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting·Listed Sep 2021

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

for Esophageal Stricture

Sites in Philadelphia, Pittsburgh +32 more locations

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561114·Phase 3·Recruiting·Listed Sep 2022

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

Sites in Philadelphia, Pittsburgh +31 more locations

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting·Listed Sep 2022

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

Sites in Philadelphia +40 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting·Listed May 2015

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

Sites in Philadelphia, Pittsburgh +23 more locations

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting·Listed Oct 2021

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A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for Treatment Resistant Depression

Sites in Philadelphia, Moosic +32 more locations

Sponsor: atai Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06524830·Phase 2·Recruiting·Listed Jul 2024

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Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Philadelphia, Pittsburgh +56 more locations

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06479135·Phase 3·Recruiting·Listed Jun 2024

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

Sites in Pittsburgh, Hershey +40 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting·Listed Nov 2019

Apply to this trial

Tissue Repair Gel in Venous Leg Ulcers (US)

for Venous Leg Ulcer

Sites in Philadelphia +26 more locations

Sponsor: TR Therapeutics

Sex: All·Age: 18+

Code: NCT06707090·Phase 3·Recruiting·Listed Nov 2024

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Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

for Irritable Bowel Syndrome

Sites in Pittsburgh +9 more locations

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT03339128·Phase 2·Recruiting·Listed Nov 2017

Apply to this trial

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

Sites in Philadelphia +66 more locations

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting·Listed Mar 2018

Apply to this trial

PARTNER 3 Trial - Aortic Valve-in-Valve

for Aortic Stenosis

Sites in Philadelphia, Pittsburgh +27 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT03003299·Recruiting·Listed Dec 2016

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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

Sites in Philadelphia, Erie +118 more locations

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting·Listed May 2023

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CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for Relapsed Hematologic Malignancy

Drug: Emavusertib

Sites in Pittsburgh +17 more locations

Sponsor: Curis, Inc.

Sex: All·Age: 18+

Code: NCT03328078·Phase 1, Phase 2·Recruiting·Listed Nov 2017

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Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

for Attention-Deficit/Hyperactivity Disorder

Sites in Hershey +46 more locations

Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All·Age: 48 Months - 69 Months

Code: NCT04781140·Phase 4·Recruiting·Listed Mar 2021

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Prospective Study to Assess a Diagnostic Aid for Cancer

for Cancer

Sites in York, Harrisburg +33 more locations

Sponsor: Harbinger Health

Sex: All·Age: 45+

Code: NCT07046260·Recruiting·Listed Jul 2025

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Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

for IgA Nephropathy

Sites in Philadelphia +36 more locations

Sponsor: Calliditas Therapeutics AB

Sex: All·Age: 18+

Code: NCT06712407·Phase 4·Recruiting·Listed Dec 2024

Apply to this trial

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

Sites in Philadelphia, Pittsburgh +35 more locations

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023

Apply to this trial

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for Aortic Dissection

Sites in Philadelphia +23 more locations

Sponsor: Endospan Ltd.

Sex: All·Age: 18+

Code: NCT04471909·Recruiting·Listed Jul 2020

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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for Neurotrophic Keratopathy

Sites in Pittsburgh +23 more locations

Sponsor: ReGenTree, LLC

Sex: All·Age: 18+

Code: NCT05555589·Phase 3·Recruiting·Listed Sep 2022

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EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

for COVID-19

Sites in Pittsburgh +23 more locations

Sponsor: Pfizer

Sex: All·Age: 0 - 17

Code: NCT05261139·Phase 3·Recruiting·Listed Mar 2022

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Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for Lung Cancer Diagnosis

Sites in Philadelphia, Lancaster +34 more locations

Sponsor: Freenome Holdings Inc.

Sex: All·Age: 50+

Code: NCT06122077·Recruiting·Listed Nov 2023

Apply to this trial