Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized Patients

for Acute Kidney Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06954129·Phase 4·Recruiting

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Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

for Glioblastoma

9 locations incl. Boston

Sponsor: Alpheus Medical, Inc.

Sex: All·Age: 18 - 80

Code: NCT07225621·Phase 2·Recruiting

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Brain-Stomach Circuits in Chronic Nausea

for Chronic Nausea and Vomiting Syndrome

1 location in Pittsburgh

Sponsor: David Levinthal

Sex: All·Age: 21 - 60·Accepts healthy volunteers

Code: NCT07276035·Recruiting

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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

for Eosinophilic Asthma

20 locations incl. Long Beach

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07323654·Phase 2·Recruiting

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Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease

for Stargardt Disease

3 locations incl. Bakersfield

Sponsor: Ray Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07439887·Phase 1, Phase 2·Recruiting

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A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for Acute Myeloid Leukaemia (AML)

5 locations incl. Bethesda

Sponsor: Tempus AI

Sex: All·Age: 0+

Code: NCT07154823·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

206 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

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Comparing Numbing Techniques in Mohs Micrographic Surgery

for Skin Cancer Face

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07222241·Recruiting

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Intra-aortic Balloon Counterpulsation (IABC) Compliance

for Cardiogenic Shock

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07402018·Recruiting

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A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)

for Graves' Disease

Drug: IMVT-1402

89 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07286006·Phase 2·Enrolling By Invitation

Neoadjuvant Darovasertib in Primary Uveal Melanoma

for Uveal Melanoma

35 locations incl. Scottsdale

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07015190·Phase 3·Recruiting

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Pembrolizumab Maintenance After Enfortumab Vedotin (EV)/Pembro Induction in Front-Line Metastatic Urothelial Carcinoma

for Metastatic Urothelial Carcinoma

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07221942·Phase 2·Recruiting

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Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

for Bipolar I Disorder

26 locations incl. Bentonville

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07494305·Phase 2·Recruiting

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Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma Refractory

12 locations incl. San Francisco

Sponsor: CellCentric Ltd.

Sex: All·Age: 18+

Code: NCT07096778·Phase 2·Recruiting

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A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

for Congenital Adrenal Hyperplasia

7 locations incl. Boston

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 1 - 17

Code: NCT07159841·Phase 2, Phase 3·Recruiting

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Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

for Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis

Drug: Vamifeport

18 locations incl. Gilbert

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07332091·Phase 2·Recruiting

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Activating SilverSneakers Benefits for Seniors With Osteoarthritis

for Osteoarthritis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65+

Code: NCT06782347·Recruiting

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EVR and EPO for Liver Transplant Tolerance

for Liver Transplant

3 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06832189·Phase 1·Recruiting

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The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment

for IVF

1 location in Villanova

Sponsor: Villanova University

Sex: Female·Age: 18+

Code: NCT07415850·Not Yet Recruiting

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

for B-ALL

4 locations incl. Philadelphia

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT06579469·Recruiting

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Respiratory Monitoring System That Detects & Predicts OIRD

for Respiration Disorders

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07217197·Enrolling By Invitation

Evaluation of the PPAL

for Age Problems

1 location in Pittsburgh

Sponsor: Alicia Koontz

Sex: All·Age: 18+

Code: NCT07221552·Recruiting

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A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

13 locations incl. Little Rock

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting

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A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis

for Dermatitis, Atopic

12 locations incl. Fountain Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07230860·Phase 2·Recruiting

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ctDNA Positive Patients Diagnosed With cT1bN0 and cT1cN0 TNBC

for Triple Negative Breast Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07332975·Recruiting

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ACT With CF Self-Help Toolkit

for Cystic Fibrosis (CF)

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07436351·Recruiting

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Optimizing Integrative Oncology Approaches to Address Chemotherapy-induced Peripheral Neuropathy in Gastrointestinal (GI) Cancer Patients: A SMART Pilot Study

for Peripheral Neuropathy

1 location in Philadelphia

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07501663·Recruiting

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Social Threat, Adolescent Relationships, and Suicidality Study

for Suicidal Thoughts and Behaviors

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 12 - 17

Code: NCT07294079·Recruiting

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Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation

for Amputation

1 location in Pittsburgh

Sponsor: Boninger, Michael, MD

Sex: All·Age: 22 - 70

Code: NCT05768802·Recruiting

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A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

for Colorectal Cancer

Drug: Atezolizumab

6 locations incl. Aurora

Sponsor: Kahr Bio Australia Pty Ltd

Sex: All·Age: 18+

Code: NCT07235293·Phase 2·Recruiting

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Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema

for Head and Neck Cancer

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06837480·Recruiting

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A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

for Renal Cell Carcinoma

Drug: BMS-986506

5 locations incl. Boston

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07195682·Phase 1·Recruiting

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Social Groups for Autistic Young Adults (SDARIYA)

for Autism Spectrum Disorder

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 30

Code: NCT07222982·Recruiting

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Female Concussion Head Cooling

for Concussion (Diagnosis)

1 location in University Park

Sponsor: Penn State University

Sex: Female·Age: 18 - 27

Code: NCT07303933·Not Yet Recruiting

Stress Management and Mindfulness Intervention for Patients With Sickle Cell Disease

for Sickle Cell Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07316478·Recruiting

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A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Searcy

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07321873·Phase 2·Recruiting

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Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown Location

for Pregnancy of Unknown Location

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT07469605·Recruiting

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Green Light for Post-Operative Wellness

for Surgery

1 location in Pittsburgh

Sponsor: Rebecca E Kotcher, MD

Sex: All·Age: 18+

Code: NCT07218289·Recruiting

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Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

for Gastroparesis

5 locations incl. Scottsdale

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT04661215·Recruiting

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Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test

for TBI (Traumatic Brain Injury)

1 location in Pittsburgh

Sponsor: Shawn Eagle

Sex: All·Age: 18+

Code: NCT07373509·Recruiting

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