Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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Safe & Sound Protocol in Adults With Trauma and SUD

for Substance Use Disorders

1 location in Wernersville

Sponsor: Caron Treatment Centers

Sex: All·Age: 18 - 75

Code: NCT07219056·Not Yet Recruiting

Impact of Smell Testing on Health Outcomes

for Olfactory Dysfunction

1 location in Philadelphia

Sponsor: Monell Chemical Senses Center

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07222891·Phase 2·Not Yet Recruiting

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

for Complex Aneuploidy

11 locations incl. Margate

Sponsor: Shady Grove Fertility Reproductive Science Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07227116·Recruiting

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I-DECIDE After Bronchiolitis Hospitalization

for Bronchiolitis Acute

56 locations incl. Birmingham

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Months - 24 Months

Code: NCT07243652·Recruiting

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Active Surveillance in Older Women With ER+ Breast Cancer

for Early Stage Estrogen Receptor (ER) Positive Breast Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 70+

Code: NCT07262138·Recruiting

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Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma

for Melanoma

1 location in Pittsburgh

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18+

Code: NCT07040280·Phase 2·Not Yet Recruiting

Aimmune Longitudinal Collaboration Study

for Stool Spore Colony Forming Units

2 locations incl. Ambler

Sponsor: Aimmune Therapeutics, Inc.

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07218640·Recruiting

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Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

for Peripheral Arterial Disease

Drug: Orforglipron

30 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07223593·Phase 3·Recruiting

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

50 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting

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Evaluation of Analgesia for Spine Fusion Elective Surgery in Children

for Idiopathic Scoliosis

2 locations incl. Cincinnati

Sponsor: Senthil Sadhasivam

Sex: All·Age: 10 - 18

Code: NCT06626503·Phase 3·Recruiting

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A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

for Eosinophilic Esophagitis

41 locations incl. Little Rock

Sponsor: Phathom Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06851559·Phase 2·Recruiting

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Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

for Pompe Disease

9 locations incl. Irvine

Sponsor: Shionogi

Sex: All·Age: 18+

Code: NCT07123155·Phase 2·Recruiting

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A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

for HNSCC

9 locations incl. Denver

Sponsor: Normunity AccelCo, Inc.

Sex: All·Age: 18+

Code: NCT07182149·Phase 1·Recruiting

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An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)

for Bipolar Depression

15 locations incl. Little Rock

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 75

Code: NCT07217860·Phase 3·Enrolling By Invitation

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

for Meniere's Disease

9 locations incl. Los Angeles

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18 - 75

Code: NCT06859788·Phase 3·Recruiting

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Improving Access to Care for Veterans With Memory Loss

for Alzheimer Disease

1 location in Pittsburgh

Sponsor: VA Pittsburgh Healthcare System

Sex: All·Age: 18+

Code: NCT07117162·Recruiting

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Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for Geographic Atrophy (GA)

27 locations incl. Gilbert

Sponsor: ONL Therapeutics

Sex: All·Age: 55+

Code: NCT06659445·Phase 2·Recruiting

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Parent Encouragement And Coaching of Happiness in Youth

for Depression

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 4 - 99·Accepts healthy volunteers

Code: NCT06725160·Recruiting

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Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

for Paroxysmal Nocturnal Hemoglobinuria (PNH)

Drug: Iptacopan

3 locations incl. New Brunswick

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 18

Code: NCT06934967·Phase 3·Recruiting

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Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study

for Esophageal Atresia With Tracheo-esophageal Fistula

2 locations incl. Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 18

Code: NCT07100379·Recruiting

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The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy

for Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy

5 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 16+

Code: NCT06599697·Phase 2·Recruiting

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A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

for Colorectal Cancer

9 locations incl. New Haven

Sponsor: Criterium, Inc.

Sex: All·Age: 18+

Code: NCT06992258·Phase 2·Recruiting

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NavSTAR Implementation Effectiveness Trial Across a Health System

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: Friends Research Institute, Inc.

Sex: All·Age: 18+

Code: NCT07262190·Recruiting

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A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Divarasib

44 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06793215·Phase 3·Recruiting

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BoxX-NoAF Clinical Trial

for Post Operative Atrial Fibrillation

14 locations incl. Jonesboro

Sponsor: AtriCure, Inc.

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06989775·Recruiting

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A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease

for Dry Eye Disease

32 locations incl. Phoenix

Sponsor: Bausch & Lomb Incorporated

Sex: All·Age: 18+

Code: NCT07128628·Phase 2·Recruiting

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Adaptive Radiation Boost for Rectal Cancer

for Rectum Cancer, Adenocarcinoma

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07221058·Phase 1·Recruiting

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The HEARTFELT Study

for Heart Failure

2 locations incl. Hackensack

Sponsor: Heartfelt Technologies

Sex: All·Age: 22+

Code: NCT06222099·Recruiting

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A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

for Haemophilia A

5 locations incl. Aurora

Sponsor: Novo Nordisk A/S

Sex: Male·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07220564·Phase 1·Recruiting

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A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

for Friedreich's Ataxia (FA)

3 locations incl. Los Angeles

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 18 - 40

Code: NCT07180355·Phase 1·Recruiting

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A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for Ovarian Neoplasms

20 locations incl. Newport Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213791·Phase 1·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

for Asthma

Drug: Brenipatide

17 locations incl. Tempe

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07219173·Phase 2·Recruiting

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

17 locations incl. Little Rock

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting

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PopSci CHW4CervixHealth

for Cervical Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07336134·Recruiting

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Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis

for Pancreatic Insufficiency

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06995651·Phase 1·Recruiting

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A Study of JNT-517 in Participants With Phenylketonuria (PKU)

for Phenylketonuria

10 locations incl. Los Angeles

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18+

Code: NCT06971731·Phase 3·Recruiting

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Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

for Chronic Pruritus of Unknown Origin

Drug: Nemolizumab

25 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT07074977·Phase 2·Recruiting

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A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia

3 locations incl. New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 1+

Code: NCT07223021·Phase 3·Recruiting

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CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

for Endometrial Cancer

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT07278986·EARLY_Phase 1·Recruiting

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