Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

Filter results

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

3,012 clinical trials

Get a weekly email when new trials open in Philadelphia, PA.

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Pittsburgh +12 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in Philadelphia +9 more locations

Sponsor: Airiver Medical, Inc.

Sex: All·Age: 18+

Code: NCT07290140·Recruiting·Listed Dec 2025

Apply to this trial

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

for Ewing Sarcoma

Sites in Philadelphia +5 more locations

Sponsor: Amgen

Sex: All·Age: 2+

Code: NCT07297979·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease

for Stargardt Disease

Sites in Pittsburgh +2 more locations

Sponsor: Ray Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07439887·Phase 1, Phase 2·Recruiting·Listed Feb 2026

Apply to this trial

A Study of CDX-622 in Participants With Mild to Moderate Asthma

for Mild to Moderate Asthma

Sites in Pittsburgh +3 more locations

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07330778·Phase 1·Recruiting·Listed Jan 2026

Apply to this trial

A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis

for Moderate to Severe Atopic Dermatitis

Sites in Philadelphia +5 more locations

Sponsor: Sitryx Therapeutics Ltd

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07558668·Phase 1·Recruiting·Listed Apr 2026

Apply to this trial

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

for Colorectal Cancer

Sites in Pittsburgh +5 more locations

Sponsor: Exero Medical Ltd.

Sex: All·Age: 21+

Code: NCT07337590·Recruiting·Listed Jan 2026

Apply to this trial

EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

for Diffuse Cutaneous Systemic Sclerosis

Sites in Philadelphia, Pittsburgh +21 more locations

Sponsor: Mediar Therapeutics

Sex: All·Age: 18+

Code: NCT07287670·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria

for Phenylketonuria

Sites in Pittsburgh +2 more locations

Sponsor: Agios Pharmaceuticals, Inc.

Sex: All·Age: 18 - 69

Code: NCT07241234·Phase 1·Recruiting·Listed Nov 2025

Apply to this trial

Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia

for Fibromyalgia

Sites in Philadelphia +7 more locations

Sponsor: SPIRE Therapeutics Inc.

Sex: All·Age: 22+

Code: NCT07226648·Recruiting·Listed Nov 2025

Apply to this trial

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

Sites in Philadelphia +9 more locations

Sponsor: AbbVie

Sex: All·Age: 40+

Code: NCT07230288·Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

Intervascular Post-Market Clinical Follow-Up (PMCF) Registry

for Carotid Artery Diseases

Sites in Pittsburgh & Hershey

Sponsor: Intervascular

Sex: All·Age: 18+

Code: NCT07322913·Recruiting·Listed Jan 2026

Apply to this trial

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

for Chronic Lymphocytic Leukemia

Drug: Emavusertib

Sites in Pittsburgh +5 more locations

Sponsor: Curis, Inc.

Sex: All·Age: 18+

Code: NCT07271667·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

for Diabetes Mellitus, Type 1

Drug: Baricitinib

Sites in Philadelphia +6 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 35

Code: NCT07222137·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

for Diabetes Mellitus, Type 1

Drug: Baricitinib

Sites in Philadelphia +4 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 35

Code: NCT07222332·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

for Atopic Dermatitis

Drug: Afimkibart

Sites in Camp Hill +4 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07223697·Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

for Locally Advanced Solid Tumor

Sites in Philadelphia +5 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213817·Phase 1, Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

for Squamous Cell Carcinoma of Head and Neck

Sites in Philadelphia +9 more locations

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18 - 74

Code: NCT07219212·Phase 1·Recruiting·Listed Oct 2025

Apply to this trial

A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.

for Ankle Arthrodesis or Arthroplasty

Sites in Philadelphia +6 more locations

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18 - 75

Code: NCT07225751·Recruiting·Listed Nov 2025

Apply to this trial

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

for Pulmonary Hypertension

Sites in Mechanicsburg +5 more locations

Sponsor: Pulnovo Medical, Inc.

Sex: All·Age: 18 - 85

Code: NCT07214376·Recruiting·Listed Oct 2025

Apply to this trial

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

for Chronic Pain

Sites in Trevose +6 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07190807·Recruiting·Listed Sep 2025

Apply to this trial

Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

for Advanced Pheochromocytoma and Paraganglioma

Sites in Philadelphia +8 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07282587·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

for Heterozygous Familial Hypercholesterolemia

Sites in Philadelphia +9 more locations

Sponsor: Verve Therapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT06164730·Phase 1·Recruiting·Listed Dec 2023

Apply to this trial

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

for Renal Cell Carcinoma

Drug: BMS-986506

Sites in Philadelphia +4 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07195682·Phase 1·Recruiting·Listed Sep 2025

Apply to this trial

A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

for Haemophilia A

Sites in Philadelphia, Hershey +3 more locations

Sponsor: Novo Nordisk A/S

Sex: Male·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07220564·Phase 1·Recruiting·Listed Oct 2025

Apply to this trial

A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors

for Solid Tumours

Drug: BMS-986517

Sites in Pittsburgh +8 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07160725·Phase 1, Phase 2·Recruiting·Listed Sep 2025

Apply to this trial

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

for Glioblastoma

Sites in Pittsburgh +6 more locations

Sponsor: GT Medical Technologies, Inc.

Sex: All·Age: 18+

Code: NCT07195591·Phase 3·Recruiting·Listed Sep 2025

Apply to this trial

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

for Colorectal Cancer

Drug: Atezolizumab

Sites in Pittsburgh +5 more locations

Sponsor: Kahr Bio Australia Pty Ltd

Sex: All·Age: 18+

Code: NCT07235293·Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

for Non-Small Cell Lung Cancer

Sites in Philadelphia +4 more locations

Sponsor: Fate Therapeutics

Sex: All·Age: 18+

Code: NCT07216105·Phase 1·Recruiting·Listed Oct 2025

Apply to this trial

Neuralert Stroke Monitor Trial

for Surgery

1 location in Philadelphia

Sponsor: Neuralert Technologies LLC

Sex: All·Age: 22+

Code: NCT07362303·Recruiting·Listed Jan 2026

Apply to this trial

A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema

for Atopic Dermatitis

Sites in Pittsburgh +9 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 64

Code: NCT07216027·Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for Acute Myeloid Leukaemia (AML)

Sites in York +9 more locations

Sponsor: Tempus AI

Sex: All·Age: 0+

Code: NCT07154823·Recruiting·Listed Sep 2025

Apply to this trial

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Sites in Bethlehem +5 more locations

Sponsor: Complement Therapeutics

Sex: All·Age: 55+

Code: NCT07144137·Recruiting·Listed Aug 2025

Apply to this trial

An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

for Multiple System Atrophy

Sites in Pittsburgh +7 more locations

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30+

Code: NCT07197866·Phase 2·Recruiting·Listed Sep 2025

Apply to this trial

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

for Congenital Heart Disease

Sites in Philadelphia +8 more locations

Sponsor: Starlight Cardiovascular Inc

Sex: All·Age: 1 Minute - 6 Months

Code: NCT07114718·Recruiting·Listed Aug 2025

Apply to this trial

A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

for Catecholaminergic Polymorphic Ventricular Tachycardia

Sites in Philadelphia +3 more locations

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 7+

Code: NCT07148089·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

for ADHD

1 location in Philadelphia

Sponsor: Gaize

Sex: All·Age: 18 - 65

Code: NCT07389473·Recruiting·Listed Feb 2026

Apply to this trial

COPD Exacerbation Follow Up

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Philadelphia +4 more locations

Sponsor: Viz.ai, Inc.

Sex: All·Age: 40+

Code: NCT07118306·Recruiting·Listed Aug 2025

Apply to this trial

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

for Non-Small Cell Lung Cancer

Sites in Philadelphia +8 more locations

Sponsor: Pierre Fabre Medicament

Sex: All·Age: 18+

Code: NCT06043817·Phase 1, Phase 2·Recruiting·Listed Sep 2023

Apply to this trial

Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy

for Cytokine Release Syndrome

Sites in Pittsburgh +5 more locations

Sponsor: CytoAgents, Inc.

Sex: All·Age: 18+

Code: NCT05905328·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial