Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma

for Uveal Melanoma

Drug: Tebentafusp

3 locations incl. Aurora

Sponsor: Diwakar Davar

Sex: All·Age: 18+

Code: NCT06070012·Phase 2·Recruiting

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A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer

for Non Small Cell Lung Cancer

8 locations incl. Oxnard

Sponsor: Wayshine Biopharm, Inc.

Sex: All·Age: 18+

Code: NCT06868485·Phase 2·Recruiting

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An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

for Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

9 locations incl. La Jolla

Sponsor: Tisento Therapeutics

Sex: All·Age: All ages

Code: NCT06961344·Phase 2·Enrolling By Invitation

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

for Autoimmune Haemolytic Anaemia

23 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07086976·Phase 3·Recruiting

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Telehealth Collaborative Care Model (CoCM) in Lung Cancer

for Lung Cancer (Diagnosis)

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07102147·Recruiting

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Pilot Trial of Clinic-based Dating Violence Prevention Program for Adolescents and Caregivers

for Dating Violence

1 location in Monongahela

Sponsor: University of Pittsburgh

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT07039253·Recruiting

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FIBERGRAFT Aeridyan Posterolateral Fusion Study

for Degenerative Spine Disease

8 locations incl. Sacramento

Sponsor: DePuy Synthes Products, Inc.

Sex: All·Age: 18+

Code: NCT07059065·Recruiting

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Angiography and Electrogram Guided Bachmann Bundle Pacing

for Heart Diseases

1 location in Wilkes-Barre

Sponsor: Pugazhendhi Vijayaraman

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07110922·Recruiting

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A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

17 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06948318·Phase 3·Recruiting

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A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

for Epileptic Encephalopathy

6 locations incl. San Diego

Sponsor: Praxis Precision Medicines

Sex: All·Age: 1 Day - 18

Code: NCT07019922·Phase 3·Recruiting

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Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

22 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting

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Near-InfraRed Spectroscopy of Auricular Stimulation

for Healthy Male and Female Subjects

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06825364·Recruiting

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Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch

for Pouchitis

5 locations incl. Los Angeles

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 80

Code: NCT06864403·Phase 4·Recruiting

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A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

for Advanced Solid Tumor

18 locations incl. Phoenix

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07070232·Phase 1, Phase 2·Recruiting

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A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

19 locations incl. Auburn

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT07096674·Phase 2·Recruiting

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A Long-Term Study of JNT-517 in Participants With Phenylketonuria

for Phenylketonuria (PKU)

8 locations incl. Gainesville

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 4+

Code: NCT06628128·Phase 3·Recruiting

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Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for Prurigo Nodularis

Drug: Nemolizumab

39 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT06988618·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT

for Refractory Ventricular Tachycardia

5 locations incl. Birmingham

Sponsor: Thermedical, Inc.

Sex: All·Age: 18+

Code: NCT05337241·Recruiting

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Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders

for Bleeding Disorders

1 location in Pittsburgh

Sponsor: Nicoletta C Machin

Sex: All·Age: 15+

Code: NCT07083583·Recruiting

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A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

for Bipolar Disorder

28 locations incl. Tucson

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07172516·Phase 3·Recruiting

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Hybrid Type I Effectiveness-implementation Cluster Randomized Controlled Trial of CARES

for CARES

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07183527·Recruiting

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Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

for Sickle Cell Disease Vaso-occlusive Crisis

16 locations incl. Oakland

Sponsor: CSL Behring

Sex: All·Age: 12+

Code: NCT06699849·Phase 2·Recruiting

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A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

for Primary Hyperaldosteronism

Drug: Baxdrostat

21 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07007793·Phase 3·Recruiting

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A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

for Alzheimer's Disease

24 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT07094516·Phase 2·Recruiting

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A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

for Melanoma (Skin Cancer)

9 locations incl. Newport Beach

Sponsor: Linnaeus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06624644·Phase 2, Phase 3·Recruiting

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Pivotal, Prospective, Multi-centre, Single-arm Study to Evaluate the Safety and Effectiveness of Oli for Identification of Patients, During the Intrapartum Period, Who Are at Higher Risk of Developing Abnormal Postpartum Uterine Bleeding, Including Postpartum Haemorrhage

for Post Partum Haemorrhage

5 locations incl. Denver

Sponsor: Baymatob Operations Pty Ltd

Sex: Female·Age: 18+

Code: NCT06655207·Recruiting

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A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for Upper Urinary Tract Urothelial Carcinoma

23 locations incl. Homewood

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT06774131·Phase 3·Recruiting

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A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for Prostate Cancer

Drug: Saruparib

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06952803·Phase 3·Recruiting

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Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

for Lewy Body Dementia Psychosis

26 locations incl. Irvine

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 84

Code: NCT07029581·Phase 2·Recruiting

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

30 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting

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A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant

for Respiratory Syncytial Virus Infections

7 locations incl. Lexington

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07092865·Phase 2·Recruiting

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A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for Breast Neoplasms

16 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07114601·Phase 1·Recruiting

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Genicular Nerve Block for Knee Pain in the ED

for Knee Pain

4 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07158736·Recruiting

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Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro

for Cataract

5 locations incl. Baltimore

Sponsor: Brian Shafer

Sex: All·Age: 18+

Code: NCT07076277·Enrolling By Invitation

Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

for Alopecia Areata

54 locations incl. Birmingham

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 12 - 17

Code: NCT07133308·Phase 3·Recruiting

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Improving Mobility After Revascularization in Peripheral Artery Disease

for Peripheral Artery Disease

7 locations incl. Tucson

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06686121·Phase 3·Recruiting

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

27 locations incl. Huntington Beach

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting

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Cholate Clearance in Fontan and Heart Failure

for Fontan

1 location in Philadelphia

Sponsor: HepQuant, LLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07009132·Recruiting

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A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

for Tophaceous Gout

Drug: Dotinurad

86 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089888·Phase 3·Recruiting

Apply to this trial