Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,650 clinical trials

↓ Download CSV

A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

for Neurotrophic Keratitis

9 locations incl. Irvine

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT06999733·Phase 1, Phase 2·Recruiting

Apply to this trial

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

for Autism

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 6 - 10

Code: NCT06386029·Recruiting

Apply to this trial

Intravesical Treatment of Bladder Cancer at Home, Multi-modal Treatment Support

for Bladder Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07048496·Recruiting

Apply to this trial

Radiation Free Study

for Aortic Aneurysm

4 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT06549348·Recruiting

Apply to this trial

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

for Castration-Resistant Prostatic Cancer

8 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06863272·Phase 1, Phase 2·Recruiting

Apply to this trial

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

for Diabetic Foot Ulcer

8 locations incl. Santa Rosa

Sponsor: Cellution Biologics

Sex: All·Age: 18+

Code: NCT07014176·Phase 4·Recruiting

Apply to this trial

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

39 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting

Apply to this trial

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for Alzheimers Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07177352·Phase 3·Recruiting

Apply to this trial

Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)

for Geriatric Assessment

3 locations incl. Princeton

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 70+

Code: NCT06870617·Recruiting

Apply to this trial

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

for Preterm Delivery

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 14+·Accepts healthy volunteers

Code: NCT06980025·Phase 3·Recruiting

Apply to this trial

Psychosocial and Behavioral Intervention for Stem Cell Transplant Patients and Their Family Caregivers

for Stem Cell Transplant

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07107165·Recruiting

Apply to this trial

OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition

for Malignant Pleural Mesothelioma

1 location in Philadelphia

Sponsor: Oncotelic Inc.

Sex: All·Age: 18+

Code: NCT05425576·Phase 2·Not Yet Recruiting

Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Pediatric and Adults Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

for Medium-chain Acyl-CoA Dehydrogenase Deficiency

1 location in Pittsburgh

Sponsor: Jerry Vockley, MD, PhD

Sex: All·Age: 4+

Code: NCT06773026·Phase 2·Recruiting

Apply to this trial

FIT-ATOMIC Exercise Feasibility Trial

for Neuroinflammatory Diseases

2 locations incl. La Jolla

Sponsor: The Hospital for Sick Children

Sex: All·Age: 11 - 25

Code: NCT06870968·Not Yet Recruiting

Thromboelastography to Study Burn Coagulopathy

for Burn

1 location in Pittsburgh

Sponsor: Francesco Egro

Sex: All·Age: 18+

Code: NCT06879509·Not Yet Recruiting

Non-invasive and Continuous Blood Pressure Monitoring

for Blood Pressure

1 location in Philadelphia

Sponsor: Vena Vitals

Sex: All·Age: 18+

Code: NCT06887465·Not Yet Recruiting

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

for Breast Cancer

134 locations incl. Daphne

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06966453·Phase 1, Phase 2·Recruiting

Apply to this trial

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

for Amyotrophic Lateral Sclerosis (ALS)

15 locations incl. Phoenix

Sponsor: Brainstorm-Cell Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06973629·Phase 3·Not Yet Recruiting

Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity

for Primary Sjögren's Syndrome

Drug: IMVT-1402

29 locations incl. Covina

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 74

Code: NCT06979531·Phase 2·Recruiting

Apply to this trial

POCUS-Guided Diuresis for Decompensated Heart Failure

for Heart Decompensation, Acute

5 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06921603·Recruiting

Apply to this trial

Dental Implant Healing With TNF-Alpha Inhibitors

for Edentulism

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06538870·Recruiting

Apply to this trial

E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

332 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting

Apply to this trial

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

for Atrial Fibrillation (AF)

12 locations incl. Jonesboro

Sponsor: Vektor Medical

Sex: All·Age: 22+

Code: NCT06935591·Recruiting

Apply to this trial

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

for Heart Failure

29 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 40 - 84

Code: NCT06979362·Phase 2·Recruiting

Apply to this trial

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

Apply to this trial

Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

Apply to this trial

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

for Sickle Cell Disease (SCD)

2 locations incl. Atlanta

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 50

Code: NCT06665997·Phase 4·Recruiting

Apply to this trial

Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

for Preterm Birth

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 16 - 55

Code: NCT06826859·Phase 1, Phase 2·Recruiting

Apply to this trial

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

37 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting

Apply to this trial

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

35 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting

Apply to this trial

CytoGam for CMV Infection or Disease in Solid Organ Transplant Recipients

for Cytomegalovirus (CMV) Infection

1 location in Pittsburgh

Sponsor: Fernanda P Silveira, MD, MS

Sex: All·Age: 18 - 75

Code: NCT07009548·Phase 4·Enrolling By Invitation

Voiceitt for People With Impairments in Speech

for Speech Impairment

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+

Code: NCT06874322·Recruiting

Apply to this trial

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

for Venous Thromboembolism (VTE)

19 locations incl. Sheffield

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07015905·Phase 3·Recruiting

Apply to this trial

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for Heart Failure With Preserved Ejection Fraction

106 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07037459·Phase 3·Recruiting

Apply to this trial

Impact of Collaborative Care for Pregnant Women With Opioid Use Disorder in Low-Resource Obstetric Settings

for Pregnancy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06956352·Enrolling By Invitation

Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

for Allergy

56 locations incl. Birmingham

Sponsor: DBV Technologies

Sex: All·Age: 1 - 3

Code: NCT07003919·Phase 3·Recruiting

Apply to this trial

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

13 locations incl. Los Angeles

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting

Apply to this trial

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

for Soft Tissue Lesion

10 locations incl. Gilbert

Sponsor: Galvanize Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05851430·Recruiting

Apply to this trial

Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

for Nausea

12 locations incl. Scottsdale

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18+

Code: NCT06464926·Recruiting

Apply to this trial