Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,650 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 8, 2026.

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3,650 clinical trials

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

149 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

59 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06959225·Phase 3·Recruiting

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

55 locations incl. Sheffield

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06961214·Phase 3·Recruiting

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Real-time NOMA Evaluation

for Critical Illness

2 locations incl. Pittsburgh

Sponsor: David T Huang

Sex: All·Age: 18 - 100

Code: NCT06996626·Recruiting

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A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: Pegcetacoplan

68 locations incl. Gilbert

Sponsor: Apellis Pharmaceuticals, Inc.

Sex: All·Age: 60+

Code: NCT07215390·Phase 2·Recruiting

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Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

for Stroke

1 location in Pittsburgh

Sponsor: Jorge Gonzalez-Martinez

Sex: All·Age: 18 - 75

Code: NCT06303869·Recruiting

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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

50 locations incl. Peoria

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06972446·Phase 2·Recruiting

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PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma

for Refractory Neuroblastoma

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 1+

Code: NCT07007117·Phase 1·Recruiting

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

24 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting

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Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

for Locally Advanced Pancreatic Adenocarcinoma

7 locations incl. Scottsdale

Sponsor: EXACT Therapeutics AS

Sex: All·Age: 18+

Code: NCT06850623·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

for Major Depressive Disorder (MDD)

28 locations incl. Chino

Sponsor: Seaport Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07065240·Phase 2·Recruiting

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ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

for Aortic Regurgitation

24 locations incl. Burlingame

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: All ages

Code: NCT06608823·Recruiting

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Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

for Childhood Astrocytoma

20 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 22

Code: NCT06894979·Phase 1·Recruiting

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Integrated Telemedicine Program Evaluation

for Behavioral Intervention

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18+

Code: NCT07042477·Recruiting

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Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

for Peripheral Neuropathies

6 locations incl. Mesa

Sponsor: RxFunction Inc.

Sex: All·Age: 55+

Code: NCT06959277·Recruiting

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A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

for Homozygous Familial Hypercholesterolemia

4 locations incl. Park Ridge

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 12+

Code: NCT07037771·Phase 3·Recruiting

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AERA Pediatrics Registry

for Dysfunction of Eustachian Tube

6 locations incl. Palo Alto

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: Up to 18

Code: NCT07071298·Recruiting

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An Observational Study of Individuals With Isolated Dystonia

for Isolated/Primary Dystonia That Affects More Than One Region of the Body

29 locations incl. Scottsdale

Sponsor: Vima Therapeutics

Sex: All·Age: 12 - 65

Code: NCT07111663·Recruiting

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Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

for Phantom Pain Following Amputation of Lower Limb

3 locations incl. Philadelphia

Sponsor: Albert Einstein Healthcare Network

Sex: All·Age: 18 - 100

Code: NCT07044323·Recruiting

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A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

for Pressure Ulcer, Stage IV

9 locations incl. Phoenix

Sponsor: Biocomposites Ltd

Sex: All·Age: 18+

Code: NCT06283979·Phase 2·Recruiting

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BioHealx® Anal Fistula Device Post Market Surveillance Study

for Fistula-in-ano

6 locations incl. Fort Myers

Sponsor: Signum Surgical USA Inc.

Sex: All·Age: 18 - 75

Code: NCT07021742·Recruiting

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Neonatal Platelet Transfusion Threshold Trial

for Thrombocytopenia

20 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 1 Hour - 48 Hours·Accepts healthy volunteers

Code: NCT06676904·Recruiting

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Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

for Post-ligation Cardiac Syndrome

19 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 3 Months

Code: NCT06679855·Phase 3·Recruiting

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VIZ ACCESS HCM - Multi-Site Registry

for Hypertrophic Cardiomyopathy

3 locations incl. Atlanta

Sponsor: Viz.ai, Inc.

Sex: All·Age: 18+

Code: NCT07103057·Recruiting

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for Myelodysplastic Syndrome

138 locations incl. Berkeley

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06577441·Phase 2·Recruiting

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

21 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting

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Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis

for Low-grade Upper Tract Urothelial Carcinoma

Drug: Nadofaragene Firadenovec

9 locations incl. Scottsdale

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06668493·Phase 1, Phase 2·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

67 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06958211·Phase 3·Recruiting

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

34 locations incl. Laguna Hills

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting

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A Multicenter, Prospective, Clinical Trial Evaluating a Single Layer Amniotic Membrane and Standard of Care Versus Matched Controls in the Management of Nonhealing Pressure Ulcers

for Pressure Ulcer

1 location in Monroeville

Sponsor: Applied Biologics, LLC

Sex: All·Age: 18+

Code: NCT07126886·Phase 4·Recruiting

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Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)

for Cerebral Aneurysms

9 locations incl. Park Ridge

Sponsor: Cerus Endovascular, Inc.

Sex: All·Age: 18 - 75

Code: NCT06693011·Recruiting

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Combined Oral Contraceptive Pill and Resistance Starch

for Metabolic Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 40

Code: NCT06852365·Phase 2·Recruiting

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REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

for Angelman Syndrome

15 locations incl. Los Angeles

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 50

Code: NCT06914609·Phase 3·Recruiting

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A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

for Facioscapulohumeral Muscular Dystrophy

14 locations incl. Orange

Sponsor: Avidity Biosciences, Inc.

Sex: All·Age: 16 - 70

Code: NCT07038200·Phase 3·Recruiting

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Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

for Agitation

53 locations incl. Homewood

Sponsor: Celgene

Sex: All·Age: 55 - 90

Code: NCT06808984·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for Autosomal Dominant Polycystic Kidney Disease

35 locations incl. Garden Grove

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18 - 55

Code: NCT06902558·Phase 2·Recruiting

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Fontan Fitness Trial

for Single-ventricle

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 17

Code: NCT06918795·Recruiting

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A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

for Friedreich Ataxia

7 locations incl. Los Angeles

Sponsor: Biogen

Sex: All·Age: 2 - 15

Code: NCT06953583·Phase 3·Recruiting

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Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

for Anterior Cruciate Ligament Reconstruction Rehabilitation

1 location in Glenside

Sponsor: Arcadia University

Sex: Female·Age: 18 - 35

Code: NCT07128602·Recruiting

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