Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

for Rheumatoid Arthritis (RA)

Sites in Duncansville +2 more locations

Sponsor: SynAct Pharma Aps

Sex: All·Age: 18+

Code: NCT06671054·Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

Ceribell Delirium Data Collection Study

for Delirium

1 location in Pittsburgh

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT04962815·Recruiting·Listed Jul 2021

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Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

for Carcinoma, Non-Small-Cell Lung Cancer

Sites in Pittsburgh +4 more locations

Sponsor: Kiromic BioPharma Inc.

Sex: All·Age: 18+

Code: NCT06069570·Phase 1·Recruiting·Listed Oct 2023

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MSC EVs in Dystrophic Epidermolysis Bullosa

for Dystrophic Epidermolysis Bullosa

Sites in Philadelphia +2 more locations

Sponsor: Aegle Therapeutics

Sex: All·Age: 6 Months+

Code: NCT04173650·Phase 1, Phase 2·Recruiting·Listed Nov 2019

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A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Sites in Philadelphia, Camp Hill +1 more location

Sponsor: Brexogen Inc.

Sex: All·Age: 18+

Code: NCT06055361·Phase 1·Recruiting·Listed Sep 2023

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North American Comfilcon A Clinical Study

for Astigmatism

Sites in College +3 more locations

Sponsor: CooperVision International Limited (CVIL)

Sex: All·Age: 8 - 75

Code: NCT06902584·Recruiting·Listed Mar 2025

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M-Vizion™ Macroscopic Radiographic Study

for Revision Hip Arthroplasty

Sites in Danville +6 more locations

Sponsor: Medacta USA

Sex: All·Age: 21 - 80

Code: NCT05721859·Recruiting·Listed Feb 2023

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A Multi-Site Clinical Evaluation of the LIAISON NES FLU A/B, RSV & COVID-19 Assay in Symptomatic Patients

for Influenza a

Sites in Pittsburgh +2 more locations

Sponsor: DiaSorin Molecular LLC

Sex: All·Age: All ages

Code: NCT06672692·Recruiting·Listed Nov 2024

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A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

for Epidermolysis Bullosa Dystrophica

1 location in Pittsburgh

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 6 Months+

Code: NCT06563414·Recruiting·Listed Aug 2024

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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for Solid Tumors

Sites in Hershey +3 more locations

Sponsor: Apollomics Inc.

Sex: All·Age: 18+

Code: NCT03175224·Phase 2·Recruiting·Listed Jun 2017

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The Lily Device Trial

for Chemotherapy Induced Alopecia

Sites in Sayre +4 more locations

Sponsor: Luminate Medical, Inc.

Sex: All·Age: 18+

Code: NCT06786078·Recruiting·Listed Jan 2025

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Airway Data Collection With the Entarik Feeding Tube System

for Healthy

1 location in Philadelphia

Sponsor: Theranova, L.L.C.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06760572·Recruiting·Listed Jan 2025

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DMD Voice: Qualitative Interviews With Patients and Caregivers

for Duchenne Muscular Dystrophy (DMD)

1 location in Yardley

Sponsor: Red Nucleus Enterprise Solutions, LLC

Sex: Male·Age: 10+

Code: NCT06925269·Recruiting·Listed Apr 2025

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Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)

for Tricuspid Regurgitation

Sites in Philadelphia +8 more locations

Sponsor: Innoventric LTD

Sex: All·Age: 18 - 85

Code: NCT06212193·Recruiting·Listed Jan 2024

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OpalGenix- Personalized Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults

for Lumbar Spine Stenosis

3 locations in Pittsburgh

Sponsor: OpalGenix, Inc

Sex: All·Age: 18 - 99

Code: NCT05452694·Recruiting·Listed Jul 2022

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Personalized Postoperative Pain Management Following Thoracic Surgery in Adults

for Thoracic Surgery

4 locations in Pittsburgh

Sponsor: OpalGenix, Inc

Sex: All·Age: 18 - 99

Code: NCT05525923·Recruiting·Listed Sep 2022

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Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

for NSCLC

Sites in Pittsburgh +1 more location

Sponsor: CJ Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05877430·Phase 1, Phase 2·Recruiting·Listed May 2023

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Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration

for Age-related Wet Macular Degeneration

Sites in Philadelphia, Erie +5 more locations

Sponsor: Caregen Co. Ltd.

Sex: All·Age: 50+

Code: NCT06132035·Phase 1·Recruiting·Listed Nov 2023

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Trisol System EFS Study

for Tricuspid Regurgitation

Sites in Wynnewood +6 more locations

Sponsor: Trisol Medical

Sex: All·Age: 18+

Code: NCT04905017·Recruiting·Listed May 2021

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CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for Cardiac Valve Disease

Sites in Philadelphia +6 more locations

Sponsor: Corcym S.r.l

Sex: All·Age: All ages

Code: NCT05002543·Recruiting·Listed Aug 2021

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The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study

for Mitral Valve Insufficiency

Sites in Harrisburg +4 more locations

Sponsor: Half Moon Medical

Sex: All·Age: 21 - 95

Code: NCT04343313·Recruiting·Listed Apr 2020

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A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.

for Wounds

Sites in Pittsburgh +3 more locations

Sponsor: Molnlycke Health Care AB

Sex: All·Age: 18+

Code: NCT05588583·Recruiting·Listed Oct 2022

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Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques

for Psoriasis

Sites in Philadelphia +2 more locations

Sponsor: SFA Therapeutics

Sex: All·Age: 18+

Code: NCT05642182·Phase 1·Recruiting·Listed Dec 2022

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Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA

for Amputation

1 location in Pittsburgh

Sponsor: Sara Peterson-Snyder

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06830876·Recruiting·Listed Feb 2025

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Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

for Venous Leg Ulcer (VLU)

1 location in Monroeville

Sponsor: Kerecis Ltd.

Sex: All·Age: 18+

Code: NCT06693570·Phase 4·Recruiting·Listed Nov 2024

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Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)

for Homocystinuria Due to CBS Deficiency

Sites in Philadelphia +2 more locations

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 65

Code: NCT02998710·Recruiting·Listed Dec 2016

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MASA Valve Early Feasibility Study

for Tetrology of Fallot

Sites in Philadelphia +4 more locations

Sponsor: PECA Labs

Sex: All·Age: 0 - 22

Code: NCT05452720·Recruiting·Listed Jul 2022

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Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

for Diabetic Foot Ulcer

1 location in Monroeville

Sponsor: MiMedx Group, Inc.

Sex: All·Age: 18+

Code: NCT06600724·Recruiting·Listed Sep 2024

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A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing

for Wounds

Sites in Pittsburgh +2 more locations

Sponsor: Molnlycke Health Care AB

Sex: All·Age: 18+

Code: NCT05608317·Recruiting·Listed Nov 2022

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Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

for Colorectal Neoplasms

Sites in Philadelphia +5 more locations

Sponsor: Surgimab

Sex: All·Age: 18+

Code: NCT03659448·Phase 3·Recruiting·Listed Sep 2018

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Reduction of Adverse Drug Events and Readmissions

for Pharmacogenomic Testing for Medication Management

1 location in York

Sponsor: ClinLogic LLC

Sex: All·Age: 25+·Accepts healthy volunteers

Code: NCT02738047·Recruiting·Listed Apr 2016

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Removing Surrogates Uncertainty to Reduce Fear and Anxiety After Cardiac Events - Kids

for Cardiac Arrest

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 Days - 17

Code: NCT07707037·Recruiting·Listed Jul 16, 2026

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Reward Sensitivity Digital Intervention for Suicide Risk

for Suicidal Ideation

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 13 - 17

Code: NCT07661901·Recruiting·Listed Jun 2026

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Smartphone-based Intervention for Young Adults With ADHD

for Attention Deficit/Hyperactivity Disorder(ADHD)

1 location in Pittsburgh

Sponsor: Traci Kennedy

Sex: All·Age: 18 - 25

Code: NCT07654205·Recruiting·Listed Jun 2026

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Intervention to Improve Parent Communication About Sexuality

for HIV/STI Incidence

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 12 - 100·Accepts healthy volunteers

Code: NCT07672067·Recruiting·Listed Jun 2026

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18F-FTHA IMAGING OF THE INTESTINAL AND CENTRAL LYMPHATIC SYSTEM

for Lymphatic Obstruction

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07645573·EARLY_Phase 1·Recruiting·Listed Jun 2026

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A Mixed-Methods Metabolomics Investigation of Lifestyle and Energy Balance During Breast Cancer Survivorship

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT07655934·Recruiting·Listed Jun 2026

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

Sites in Elkins Park +12 more locations

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting·Listed May 2026

Apply to this trial

The Effects of Strength Training on Muscle Mass and Mental Health in Adults Taking Obesity Medication

for Muscle Composition

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT07652333·Recruiting·Listed Jun 2026

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Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

for Delirium in the Intensive Care Unit

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07649876·Recruiting·Listed Jun 2026

Apply to this trial