Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 24

Code: NCT07270016·Recruiting·Listed Dec 2025

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Social Threat, Adolescent Relationships, and Suicidality Study

for Suicidal Thoughts and Behaviors

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 12 - 17

Code: NCT07294079·Recruiting·Listed Dec 2025

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COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

for Ulcerative Colitis, Pediatric

Sites in Pittsburgh +3 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 1 - 18

Code: NCT07198113·Recruiting·Listed Sep 2025

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Little Cigar Oxidants

for Tobacco Use

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21 - 65

Code: NCT06310187·Recruiting·Listed Mar 2024

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Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

for Diabetes in Adolescence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07216118·Recruiting·Listed Oct 2025

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CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

for SLE

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 29

Code: NCT06839976·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

Sites in Pittsburgh +17 more locations

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting·Listed Nov 2019

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Quantifying New Heart Muscle Cells

for Tetralogy of Fallot With Pulmonary Stenosis

Sites in Philadelphia, Pittsburgh +2 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 30 Days - 1

Code: NCT06587165·Recruiting·Listed Sep 2024

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QOL and Sarcopenia in Patients With Ascites

for Ascites Hepatic

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05726747·Recruiting·Listed Feb 2023

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Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)

for Atrial Fibrillation (AF)

1 location in Hershey

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT07002450·Recruiting·Listed Jun 2025

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Pollution Intervention to Impact Kids Asthma Study

for Childhood Asthma

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 8 - 17

Code: NCT07261423·Recruiting·Listed Dec 2025

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Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

for Repetitive Head Impacts

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 30 - 70

Code: NCT07050173·Phase 1·Recruiting·Listed Jul 2025

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BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia

for Endotracheal Extubation

Sites in Philadelphia +1 more location

Sponsor: Telethon Kids Institute

Sex: All·Age: 0 - 16

Code: NCT07204990·Recruiting·Listed Oct 2025

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Pilot Trial of Clinic-based Dating Violence Prevention Program for Adolescents and Caregivers

for Dating Violence

1 location in Monongahela

Sponsor: University of Pittsburgh

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT07039253·Recruiting·Listed Jun 2025

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Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

for Opioid Withdrawal

1 location in Pittsburgh

Sponsor: Payel Roy

Sex: All·Age: 18+

Code: NCT07079826·Recruiting·Listed Jul 2025

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Intramedullary Calcium Sulfate Antibiotic Depot

for Open tíbia Fracture

Sites in Hershey +9 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05766670·Phase 3·Recruiting·Listed Mar 2023

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Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)

for Esophageal Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06872515·Recruiting·Listed Mar 2025

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Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

for Adults With Variability in Their Mood

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07252011·Recruiting·Listed Nov 2025

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Philadelphia, Pittsburgh +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Telehealth Collaborative Care Model (CoCM) in Lung Cancer

for Lung Cancer (Diagnosis)

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07102147·Recruiting·Listed Aug 2025

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Study of Individuals Affected With Hypoplasminogenemia

for Plasminogen Deficiency

Sites in Pittsburgh +10 more locations

Sponsor: Indiana Hemophilia &Thrombosis Center, Inc.

Sex: All·Age: All ages

Code: NCT03797495·Recruiting·Listed Jan 2019

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Neoadjuvant Tebentafusp for Uveal Melanoma

for Locally Advanced Unresectable Uveal Melanoma

Drug: Tebentafusp

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06414590·Phase 2·Recruiting·Listed May 2024

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Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

for Pain, Postoperative

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT03737292·Phase 4·Recruiting·Listed Nov 2018

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A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

for Obesity

Sites in Philadelphia +2 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 25 - 59

Code: NCT05748158·Recruiting·Listed Feb 2023

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Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

for Neuroblastoma

Sites in Hershey +19 more locations

Sponsor: Giselle Sholler

Sex: All·Age: Up to 22

Code: NCT02559778·Phase 2·Recruiting·Listed Sep 2015

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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for Pediatric Patients Treated With Radiation Therapy

Sites in Philadelphia +22 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 21

Code: NCT01696721·Recruiting·Listed Oct 2012

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MyPaTH Story Booth

for Narrative Medicine

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 99

Code: NCT03494075·Recruiting·Listed Apr 2018

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ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

Sites in Philadelphia +4 more locations

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting·Listed Feb 2021

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Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV

for HIV Infections

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 80

Code: NCT05502653·Recruiting·Listed Aug 2022

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Tele-Exercise to Promote Empowered Movement in Individuals With Spinal Cord Injury

for Spinal Cord Injury

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 75

Code: NCT07022808·Recruiting·Listed Jun 2025

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Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

for Williams Beuren Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06930417·Recruiting·Listed Apr 2025

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Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

for Rectal Adenocarcinoma

Sites in Allentown +9 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04165772·Phase 2·Recruiting·Listed Nov 2019

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

Sites in Pittsburgh +4 more locations

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting·Listed Jun 2024

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Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

for Non-small Cell Lung Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04332367·Phase 2·Recruiting·Listed Apr 2020

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NEPTUNE Match Study

for Nephrotic Syndrome in Children

Sites in Philadelphia +15 more locations

Sponsor: University of Michigan

Sex: All·Age: 1 - 80

Code: NCT04571658·Recruiting·Listed Oct 2020

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MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

for Anal Squamous Cell Carcinoma

Sites in Pittsburgh +1 more location

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT06050707·Phase 2·Recruiting·Listed Sep 2023

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Philadelphia, Pittsburgh +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

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Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

for Hematologic Neoplasms

Sites in Philadelphia +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 85·Accepts healthy volunteers

Code: NCT04959175·Phase 1, Phase 2·Recruiting·Listed Jul 2021

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Synovial Sarcoma Registry / Biospecimen Repository

for Synovial Sarcoma

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT05910307·Recruiting·Listed Jun 2023

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Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Pediatric and Adults Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

for Medium-chain Acyl-CoA Dehydrogenase Deficiency

1 location in Pittsburgh

Sponsor: Jerry Vockley, MD, PhD

Sex: All·Age: 4+

Code: NCT06773026·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial