Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 10, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,657 clinical trials

↓ Download CSV

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

for Sickle Cell Disease (SCD)

31 locations incl. Birmingham

Sponsor: University of Rochester

Sex: All·Age: 3 - 20

Code: NCT06941389·Recruiting

Apply to this trial

Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)

for Ovarian Cancer

6 locations incl. Phoenix

Sponsor: NX Development Corp

Sex: Female·Age: 18+

Code: NCT05804370·Phase 3·Recruiting

Apply to this trial

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

for Muscular Atrophy, Spinal

11 locations incl. Little Rock

Sponsor: Hoffmann-La Roche

Sex: All·Age: 3 Months - 24 Months

Code: NCT05861986·Phase 4·Recruiting

Apply to this trial

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

for Anatomic Stage I Breast Cancer

5 locations incl. Atlanta

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT05919108·Phase 2·Recruiting

Apply to this trial

Feasibility of a Mindfulness Intervention for Endometriosis Surgery

for Endometriosis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: Female·Age: 18+

Code: NCT06141720·Recruiting

Apply to this trial

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

for Thyroid Eye Disease

9 locations incl. Little Rock

Sponsor: Amgen

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06401044·Phase 1, Phase 2·Recruiting

Apply to this trial

Treatment With Aspirin After Preeclampsia: TAP Trial

for Hypertensive Disorder of Pregnancy

1 location in Pittsburgh

Sponsor: Malamo Countouris

Sex: Female·Age: 18 - 55

Code: NCT06281665·Phase 4·Recruiting

Apply to this trial

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06296394·Recruiting

Apply to this trial

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

for Pediatric

Drug: Aficamten

26 locations incl. Phoenix

Sponsor: Cytokinetics

Sex: All·Age: 12 - 17

Code: NCT06412666·Phase 2, Phase 3·Recruiting

Apply to this trial

Impella RP Flex with Smart Assist

for Right Ventricular (RV) Dysfunction

31 locations incl. Birmingham

Sponsor: Abiomed Inc.

Sex: All·Age: All ages

Code: NCT06637644·Recruiting

Apply to this trial

Managing Chronic Tendon Pain by Metformin

for Tendinopathy

1 location in Pittsburgh

Sponsor: James Wang

Sex: All·Age: 18 - 50

Code: NCT06100822·Phase 1·Recruiting

Apply to this trial

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for Non-small Cell Lung Cancer

Drug: Calderasib

15 locations incl. Bakersfield

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06345729·Phase 3·Recruiting

Apply to this trial

Multi-Center Clean Air Randomized Controlled Trial in COPD

for Chronic Obstructive Pulmonary Disease (COPD)

11 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 40+

Code: NCT06376994·Phase 3·Recruiting

Apply to this trial

First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

for Select Advanced Solid Tumors

4 locations incl. Miami

Sponsor: CDR-Life AG

Sex: All·Age: 18+

Code: NCT06402201·Phase 1·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

135 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting

Apply to this trial

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

32 locations incl. Chandler

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

for Thrombocythemia, Essential

4 locations incl. Ann Arbor

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06351631·Phase 3·Recruiting

Apply to this trial

Advancing Transplantation Outcomes in Children

for Kidney Transplant

20 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 13 - 20

Code: NCT06055608·Phase 2·Recruiting

Apply to this trial

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

13 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting

Apply to this trial

Game-based Pediatric Diabetes Education

for Diabetes Mellitus, Type 1

1 location in Pittsburgh

Sponsor: Carnegie Mellon University

Sex: All·Age: 6 - 12·Accepts healthy volunteers

Code: NCT06264258·Recruiting

Apply to this trial

PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC

for Head and Neck Squamous Cell Carcinoma

Drug: Rilvegostomig

7 locations incl. Sacramento

Sponsor: Presage Biosciences

Sex: All·Age: 18+

Code: NCT06366451·EARLY_Phase 1·Recruiting

Apply to this trial

Screening Emotions in Adolescents at the Hospital for mTBI

for Brain Injury Traumatic Mild

6 locations incl. Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 11 - 17

Code: NCT06370520·Recruiting

Apply to this trial

A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

for Acute Myeloid Leukemias

26 locations incl. Burbank

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06226571·Phase 1·Recruiting

Apply to this trial

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants

for Peri-Implantitis

1 location in Pittsburgh

Sponsor: Andrea Ravida

Sex: All·Age: 18 - 80

Code: NCT06430268·Enrolling By Invitation

A Study of Emapalumab for Pediatric Aplastic Anemia

for Aplastic Anemia

6 locations incl. New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 0 - 25·Accepts healthy volunteers

Code: NCT06430788·Phase 2·Recruiting

Apply to this trial

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

84 locations incl. Huntsville

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting

Apply to this trial

Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy

for Prostate Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: 18+

Code: NCT06296147·Recruiting

Apply to this trial

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for Asthma

105 locations incl. Anchorage

Sponsor: AstraZeneca

Sex: All·Age: 12 - 17

Code: NCT06307665·Phase 3·Recruiting

Apply to this trial

Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy

for Food Allergy

Drug: Linvoseltamab

5 locations incl. Tampa

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 50

Code: NCT06369467·Phase 1·Recruiting

Apply to this trial

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

for Cerebral Amyloid Angiopathy

34 locations incl. Los Angeles

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 30+

Code: NCT06393712·Phase 2·Recruiting

Apply to this trial

Boosting Resources for Tracheostomy Care at Home

for Tracheostomy

6 locations incl. La Jolla

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06283953·Enrolling By Invitation

Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies

for Upper Abdominal Malignancies

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06355895·Recruiting

Apply to this trial

Vaginal Ecosystem and Network in the United States Study

for Bacterial Vaginosis

20 locations incl. Fullerton

Sponsor: Vaginal Biome Science

Sex: Female·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06472765·Enrolling By Invitation

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

for Neuroendocrine Tumors

4 locations incl. Atlanta

Sponsor: Chimeric Therapeutics

Sex: All·Age: 18 - 85

Code: NCT06055439·Phase 1, Phase 2·Recruiting

Apply to this trial

A Registry for People With Lung Cancer

for Lung Cancer

15 locations incl. Tucson

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06424327·Recruiting

Apply to this trial

Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

65 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06309966·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

for Advanced or Metastatic Solid Tumors

14 locations incl. Phoenix

Sponsor: 858 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06395519·Phase 1, Phase 2·Recruiting

Apply to this trial

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma

for Pancreatic Ductal Adenocarcinoma

5 locations incl. Lake Success

Sponsor: Gulam Manji

Sex: All·Age: 18+

Code: NCT06048484·Phase 2·Recruiting

Apply to this trial

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

for Healthy Participants

9 locations incl. Glendale

Sponsor: Equilibra Bioscience LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06349473·Phase 1·Recruiting

Apply to this trial

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

for Kidney Transplant

3 locations incl. Boston

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 65

Code: NCT06056102·Phase 1·Recruiting

Apply to this trial