Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 10, 2026.

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3,657 clinical trials

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A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)

for Chronic Myeloid Leukemia, Chronic Phase

18 locations incl. Birmingham

Sponsor: Terns, Inc.

Sex: All·Age: 18+

Code: NCT06163430·Phase 1, Phase 2·Recruiting

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The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

for Polycystic Ovary Syndrome

24 locations incl. Encino

Sponsor: May Health

Sex: Female·Age: 18 - 40

Code: NCT06206746·Recruiting

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

18 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting

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Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

7 locations incl. Birmingham

Sponsor: Molecure S.A.

Sex: All·Age: 18+

Code: NCT06205121·Phase 2·Recruiting

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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for Neoplasms, Head and Neck

Drug: Dostarlimab

36 locations incl. Jonesboro

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06256588·Phase 3·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

for Physical Inactivity

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT05826379·Enrolling By Invitation

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05897788·Recruiting

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Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

for Insomnia

3 locations incl. Denver

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06281756·EARLY_Phase 1·Recruiting

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Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

for Attention-Deficit/Hyperactivity Disorder

47 locations incl. Saraland

Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All·Age: 48 Months - 69 Months

Code: NCT04781140·Phase 4·Recruiting

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

52 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting

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A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for Low Grade Serous Ovarian Cancer

Drug: Avutometinib

38 locations incl. Phoenix

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT06072781·Phase 3·Recruiting

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ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

for Aortic Valve Stenosis

67 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT05932615·Enrolling By Invitation

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for Systemic Lupus Erythematosus

22 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 5 - 17

Code: NCT05835310·Phase 3·Recruiting

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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

61 locations incl. Phoenix

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting

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A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

for Crohn's Disease

15 locations incl. Los Angeles

Sponsor: Eli Lilly and Company

Sex: All·Age: 2 - 17

Code: NCT05509777·Phase 3·Recruiting

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A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Guselkumab

14 locations incl. Los Angeles

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2 - 17

Code: NCT05923073·Phase 3·Recruiting

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Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response

for Primary Central Nervous System Lymphoma

7 locations incl. New York

Sponsor: Providence Health & Services

Sex: All·Age: 18+

Code: NCT06175000·Phase 2·Recruiting

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Study of AZD0754 in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

13 locations incl. Duarte

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT06267729·Phase 1, Phase 2·Recruiting

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Facilitating Access to Specialty Treatment

for Mild Traumatic Brain Injury

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 13 - 18

Code: NCT05741411·Recruiting

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Penn Medicine Healthy Heart

for Hypertension

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 35 - 80

Code: NCT06062394·Recruiting

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Effects of Ketone Supplementation on Acute Alcohol Withdrawal

for Alcohol Use Disorder

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 75

Code: NCT06173973·Phase 2, Phase 3·Enrolling By Invitation

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

for Crohn Disease

2 locations incl. Philadelphia

Sponsor: Seattle Children's Hospital

Sex: All·Age: 8 - 21

Code: NCT06216899·Recruiting

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OLE Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

for Hyperphagia in Prader-Willi Syndrome

19 locations incl. Birmingham

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 5 - 30

Code: NCT06420297·Phase 3·Enrolling By Invitation

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

59 locations incl. Duarte

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting

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A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for Aortic Stenosis

Drug: Pelacarsen

37 locations incl. Huntsville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 80

Code: NCT05646381·Phase 2·Recruiting

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RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis

for Melanoma

1 location in Pittsburgh

Sponsor: Yana Najjar

Sex: All·Age: 18+

Code: NCT06216938·EARLY_Phase 1·Recruiting

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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

124 locations incl. Miami

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting

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The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.

for Nutraceuticals

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06274385·Recruiting

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Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

for Liver Transplant

18 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06075745·Phase 2·Recruiting

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AETOS Shoulder System

for Shoulder Osteoarthritis

5 locations incl. San Francisco

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 18+

Code: NCT06319911·Recruiting

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Geisinger Antibiotic Allergy Pilot Program: Assess and Address

for Penicillin Allergy

3 locations incl. Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18+

Code: NCT05464615·EARLY_Phase 1·Recruiting

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

20 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting

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iCare4Me Transitions

for Caregiver Stress

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06167746·Phase 3·Recruiting

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An Open-label Extension Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

5 locations incl. Denver

Sponsor: Xentria, Inc.

Sex: All·Age: 18 - 80

Code: NCT06169397·Phase 2·Enrolling By Invitation

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

for Breast Cancer

673 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: All·Age: 18 - 100

Code: NCT05896189·Recruiting

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A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

for Dermatitis Atopic

Drug: Amlitelimab

42 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT06241118·Phase 3·Recruiting

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Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

for Alzheimer Disease

53 locations incl. Phoenix

Sponsor: Cognito Therapeutics, Inc.

Sex: All·Age: 50 - 92

Code: NCT06245031·Enrolling By Invitation

Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

for Malignant Solid Neoplasm

384 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06295367·Recruiting

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Nicotinamide Riboside in Ulcerative Colitis

for Ulcerative Colitis

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 18

Code: NCT05561738·Recruiting

Apply to this trial