Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 10, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,657 clinical trials

↓ Download CSV

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

for Early Breast Cancer

Drug: Ribociclib

78 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05827081·Phase 3·Recruiting

Apply to this trial

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

for Solid Cancer

43 locations incl. Anchorage

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06161025·Phase 2, Phase 3·Recruiting

Apply to this trial

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

for Paroxysmal Atrial Fibrillation

21 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06324201·Recruiting

Apply to this trial

CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML

for Leukemia, Myeloid, Acute

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05945849·Phase 1·Recruiting

Apply to this trial

SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. New Haven

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting

Apply to this trial

NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)

for Duchenne Muscular Dystrophy

10 locations incl. Aurora

Sponsor: NS Pharma, Inc.

Sex: Male·Age: 4 - 14

Code: NCT05996003·Phase 2·Recruiting

Apply to this trial

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for AML

38 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06001788·Phase 1·Recruiting

Apply to this trial

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

34 locations incl. Little Rock

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting

Apply to this trial

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

for Emphysema, Pulmonary

18 locations incl. Phoenix

Sponsor: Pulmonx Corporation

Sex: All·Age: 40 - 80

Code: NCT06035120·Recruiting

Apply to this trial

Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

for Gram-negative Bacteremia

11 locations incl. San Francisco

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06080698·Recruiting

Apply to this trial

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

for Multiple Myeloma

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06121843·Phase 1·Recruiting

Apply to this trial

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

234 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

Apply to this trial

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

for Myotonic Dystrophy Type 1 (DM1)

8 locations incl. San Carlos

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 64

Code: NCT06185764·Phase 1, Phase 2·Recruiting

Apply to this trial

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia With FLT3/ITD Mutation

4 locations incl. Chapel Hill

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT06222580·Phase 1·Recruiting

Apply to this trial

An Observational Study of Patients With Chronic Liver Disease

for Chronic Liver Disease

10 locations incl. Los Angeles

Sponsor: Target PharmaSolutions, Inc.

Sex: All·Age: 18+

Code: NCT05744713·Enrolling By Invitation

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

28 locations incl. Berkeley

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting

Apply to this trial

Effect of Zinc on Glucose Homeostasis

for Prediabetic State

1 location in Lancaster

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 80

Code: NCT05835037·Phase 4·Recruiting

Apply to this trial

A Global Prospective Observational Registry of Patients With Pompe Disease

for Pompe Disease

15 locations incl. Little Rock

Sponsor: Amicus Therapeutics

Sex: All·Age: All ages

Code: NCT06121011·Recruiting

Apply to this trial

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

21 locations incl. Orange

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

for Tauopathies

3 locations incl. New Haven

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT06303921·EARLY_Phase 1·Recruiting

Apply to this trial

Real-time fMRI for Insular Cortex Brain State-triggered Experience Sampling

for Healthy

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05855525·Recruiting

Apply to this trial

Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in West Reading

Sponsor: The Reading Hospital and Medical Center

Sex: All·Age: 18+

Code: NCT05893927·Recruiting

Apply to this trial

Getting Out of the House: Using Behavioral Activation to Increase Community Participation

for Major Depressive Disorder

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06336616·Recruiting

Apply to this trial

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

5 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting

Apply to this trial

An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

for Overweight and Obesity

1 location in Philadelphia

Sponsor: Drexel University

Sex: Female·Age: 14 - 19·Accepts healthy volunteers

Code: NCT06147973·Recruiting

Apply to this trial

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for Primary Progressive Aphasia

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT05386394·Phase 2·Recruiting

Apply to this trial

Tocilizumab in Lung Transplantation

for Lung Transplant

Drug: Tocilizumab

21 locations incl. Phoenix

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75

Code: NCT06033196·Phase 2·Recruiting

Apply to this trial

A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

for Congenital Myasthenic Syndrome

6 locations incl. Sacramento

Sponsor: argenx

Sex: All·Age: 2+

Code: NCT06078553·Recruiting

Apply to this trial

Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder

for Opioid Use Disorder

2 locations incl. Indianapolis

Sponsor: Indiana University

Sex: Female·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06415994·Enrolling By Invitation

Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

12 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting

Apply to this trial

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

15 locations incl. La Jolla

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting

Apply to this trial

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

12 locations incl. Birmingham

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting

Apply to this trial

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

30 locations incl. Daphne

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06095505·Phase 2·Recruiting

Apply to this trial

Preserving Geriatric Muscle With an Osteoporosis Medication

for Osteoporosis

1 location in Pittsburgh

Sponsor: Susan L. Greenspan

Sex: All·Age: 65+

Code: NCT06118905·Phase 4·Recruiting

Apply to this trial

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

for Multiple Myeloma

Drug: Elranatamab

97 locations incl. Mobile

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06152575·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

60 locations incl. Anchorage

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT06072482·Phase 4·Recruiting

Apply to this trial

Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors

for Chronic Lymphocytic Leukemia

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 22+

Code: NCT06211413·Enrolling By Invitation

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

for Ductal Carcinoma in Situ

1 location in Pittsburgh

Sponsor: Finn, Olivera, PhD

Sex: Female·Age: 18+

Code: NCT06218303·Phase 1·Recruiting

Apply to this trial

An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophy

for Duchenne Muscular Dystrophy

25 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: 4+

Code: NCT06270719·Enrolling By Invitation

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

for Metastatic Dedifferentiated Liposarcoma

Drug: Peposertib

16 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05711615·Phase 1·Recruiting

Apply to this trial