Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 10, 2026.

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3,657 clinical trials

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Efficacy of Liposomal Bupivacaine Post Septorhinoplasty

for Rhinoplasty

1 location in Hershey

Sponsor: Jessyka Lighthall

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05964868·Phase 3·Enrolling By Invitation

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: National Jewish Health

Sex: All·Age: 6+

Code: NCT06262282·Enrolling By Invitation

Nerve Transfer to Improve Function in High Level Tetraplegia

for Cervical Spinal Cord Injury

9 locations incl. Stanford

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06288763·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

490 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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Project OASIS: Optimizing Approaches to Select Implementation Strategies

for Cirrhosis

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06061328·Enrolling By Invitation

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

for Esophageal Cancer

10 locations incl. Boston

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06123338·Phase 2·Recruiting

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A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

for Cystic Fibrosis

13 locations incl. Birmingham

Sponsor: ReCode Therapeutics

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06237335·Phase 2·Recruiting

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

5 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting

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Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

19 locations incl. La Mesa

Sponsor: Cumberland Pharmaceuticals

Sex: All·Age: 40+

Code: NCT05571059·Phase 2·Recruiting

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TmPSMA-02 in mCRPC

for Metastatic Castrate-Resistant Prostate Cancer (mCRPC)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Male·Age: 18+

Code: NCT06046040·Phase 1·Recruiting

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Dosing of LT4 in Older Individuals

for Hypothyroidism

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT06073665·Phase 4·Recruiting

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CPI-0209 Plus Carboplatin in Patients With Platinum Sensitive Recurrent Ovarian Cancer

for Recurrent Ovarian Cancer

1 location in Pittsburgh

Sponsor: Lan Coffman

Sex: Female·Age: 18+

Code: NCT05942300·Phase 1·Recruiting

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Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer

for Malignant Pleural Effusion

Drug: Tocilizumab

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 18 - 89

Code: NCT06016179·Phase 1·Recruiting

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Enriched Holistic Care to Eradicate Disparities in Maternal Morbidity

for Morbidity

2 locations incl. Phialdelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 16 - 55·Accepts healthy volunteers

Code: NCT06245057·Recruiting

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Feasibility of Semaglutide in Advanced Lung Disease

for Obesity

Drug: Semaglutide

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT05746039·Phase 1, Phase 2·Recruiting

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Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

for Glioblastoma

19 locations incl. Phoenix

Sponsor: CarThera

Sex: All·Age: 18+

Code: NCT05902169·Phase 3·Recruiting

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Mobile Health for Adherence in Breast Cancer Patients

for Anatomic Stage IV Breast Cancer AJCC v8

499 locations incl. Fairbanks

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06112613·Recruiting

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An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

for Friedreich Ataxia

8 locations incl. Los Angeles

Sponsor: Larimar Therapeutics, Inc.

Sex: All·Age: 2 - 60

Code: NCT06447025·Phase 2·Recruiting

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The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

for Myasthenia Gravis

11 locations incl. Aurora

Sponsor: Ad scientiam

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05564936·Recruiting

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Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

for Nodular Lymphocyte Predominant B-Cell Lymphoma

Drug: Mosunetuzumab

35 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05886036·Phase 2·Recruiting

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AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

for Lymphoma

7 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT06137144·Phase 1, Phase 2·Recruiting

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A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

for SCLC

11 locations incl. Duarte

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06179069·Phase 1·Recruiting

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A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

for Beta-Thalassemia

6 locations incl. Oakland

Sponsor: Genetix Biotherapeutics Inc.

Sex: All·Age: All ages

Code: NCT06271512·Recruiting

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

for Multiple Myeloma

Drug: Talquetamab

49 locations incl. Clovis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06208150·Phase 3·Recruiting

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Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

for Oropharyngeal Cancer

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06305676·Recruiting

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A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas

for Anal Fistula

9 locations incl. Los Angeles

Sponsor: RedDress Ltd.

Sex: All·Age: 18+

Code: NCT05641844·Recruiting

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A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

for Phenylketonuria (PKU)

11 locations incl. Aurora

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT06305234·Recruiting

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Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

for Advanced Solid Tumor

4 locations incl. Bethesda

Sponsor: Ankyra Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06171750·Phase 1·Recruiting

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A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

for Advanced Solid Tumors That Are MTAP Deficient

8 locations incl. San Francisco

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06130553·Phase 1, Phase 2·Recruiting

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Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

for Non-Small Cell Lung Cancer, NSCLC

26 locations incl. Gilbert

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06162221·Phase 1, Phase 2·Recruiting

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

77 locations incl. Birmingham

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting

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A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)

for Acute Respiratory Failure

5 locations incl. Chicago

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06042621·Enrolling By Invitation

Impact of Heart Rate Variability Modulation on Stress Management Among Physicians

for Burnout, Professional

1 location in Pittsburgh

Sponsor: Michelle Thompson

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05731856·Recruiting

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Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)

for Center Involved Diabetic Macular Edema

5 locations incl. Deerfield Beach

Sponsor: Ocugen

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05802329·Phase 1·Recruiting

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Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder (BD)

for Bipolar Disorder

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06081426·Recruiting

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A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

for Metastatic Head-and-neck Squamous-cell Carcinoma

28 locations incl. Gilbert

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06064877·Phase 3·Recruiting

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LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF

for Pulmonary Hypertension

41 locations incl. Tucson

Sponsor: Tenax Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT05983250·Phase 3·Recruiting

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Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES

for Lung Cancer

3 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 35 - 89

Code: NCT05968898·Recruiting

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Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

for Ulcerative Colitis

13 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT05987852·Recruiting

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EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

for Breast Cancer

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female·Age: 20 - 89

Code: NCT06115486·Recruiting

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