Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 10, 2026.

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3,657 clinical trials

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

Apply to this trial

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Sotorasib

21 locations incl. Santa Barbara

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT05920356·Phase 3·Recruiting

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OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

47 locations incl. Tucson

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06016738·Phase 3·Recruiting

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A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)

for Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia

3 locations incl. Philadelphia

Sponsor: Autolus Limited

Sex: All·Age: 0 - 18

Code: NCT06173518·Phase 1·Recruiting

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

5 locations incl. Aurora

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting

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A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

for Secondary Progressive Multiple Sclerosis

Drug: Foralumab

7 locations incl. North Haven

Sponsor: Tiziana Life Sciences LTD

Sex: All·Age: 18 - 75

Code: NCT06292923·Phase 2·Recruiting

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The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study

for Prostate Cancer

1 location in Philadelphia

Sponsor: Vivek Narayan

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT06064149·Recruiting

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ACP-204 in Adults With Alzheimer's Disease Psychosis

for Alzheimer's Disease Psychosis

45 locations incl. Chandler

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 95

Code: NCT06159673·Phase 2, Phase 3·Recruiting

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[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

for Breast Cancer

Drug: Ribociclib

6 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05870579·Phase 1·Recruiting

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TmCD19-IL18 in CD19+ Cancers

for Non Hodgkin Lymphoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05989204·Phase 1·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting

for Infertility, Male

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Male·Age: All ages

Code: NCT04452305·Recruiting

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A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

17 locations incl. Birmingham

Sponsor: Xentria, Inc.

Sex: All·Age: 18 - 80

Code: NCT05890729·Phase 1, Phase 2·Recruiting

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LATe Cerclage in High-risk Pregnancies (LATCH)

for Premature Birth

2 locations incl. Charlotte

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06036446·Recruiting

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Assessing Patient Satisfaction and Confidence After Use of Educational Video to Augment Surgical Consent for Thyroid Surgery

for Thyroid Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06918223·Recruiting

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Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

for Neovascular Age-related Macular Degeneration

63 locations incl. Glendale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05904028·Phase 3·Recruiting

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CtDNA Based MRD Testing for NAC Monitoring in TNBC

for TNBC - Triple-Negative Breast Cancer

14 locations incl. Tucson

Sponsor: Personalis Inc.

Sex: Female·Age: 18+

Code: NCT06230185·Recruiting

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Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for Metastatic Colorectal Carcinoma

22 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05803382·Phase 1·Recruiting

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Biennial CEM in Women With a Personal History of Breast Cancer

for Breast Cancer

6 locations incl. Bethel Park

Sponsor: Wendie Berg

Sex: Female·Age: 30 - 79·Accepts healthy volunteers

Code: NCT06105749·Recruiting

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Impact of a Biophoton Therapy on Patients With Brain Disorders

for Brain Disorders - Alzheimer's Disease, Dementia, Parkinson's Disease, Traumatic Brain Injury

1 location in Butler

Sponsor: First Institute of All Medicines

Sex: All·Age: 18+

Code: NCT06147999·Recruiting

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Trial of Ixazomib for Kaposi Sarcoma

for Kaposi Sarcoma

11 locations incl. San Diego

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04305691·Phase 2·Recruiting

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Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for Cancer

17 locations incl. San Francisco

Sponsor: MBrace Therapeutics

Sex: All·Age: 18+

Code: NCT06014658·Phase 1, Phase 2·Recruiting

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Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

for Carcinoma, Non-Small-Cell Lung Cancer

5 locations incl. Tucson

Sponsor: Kiromic BioPharma Inc.

Sex: All·Age: 18+

Code: NCT06069570·Phase 1·Recruiting

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JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

for Advanced Solid Tumor

10 locations incl. Encinitas

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06108050·Phase 1·Recruiting

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Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart Failure

31 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40 - 85

Code: NCT06122779·Phase 2·Recruiting

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PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

for Cervical Cancer

3 locations incl. Voorhees Township

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05758688·Phase 2·Recruiting

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Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)

for Ileal Pouch

8 locations incl. Los Angeles

Sponsor: Exegi Pharma, LLC

Sex: All·Age: 18+

Code: NCT05938465·Phase 1, Phase 2·Recruiting

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

29 locations incl. Chandler

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

32 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting

Apply to this trial

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for Lymphoblastic Leukemia

17 locations incl. Phoenix

Sponsor: Tanja Andrea Gruber

Sex: All·Age: Up to 1

Code: NCT05848687·Phase 1, Phase 2·Recruiting

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Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

for Becker Muscular Dystrophy

24 locations incl. Little Rock

Sponsor: Edgewise Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06066580·Phase 2·Enrolling By Invitation

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

33 locations incl. Scottsdale

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting

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A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

for Prostatic Neoplasms

11 locations incl. Aurora

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT06095089·Phase 1·Recruiting

Apply to this trial

Integrating Brain, Neurocognitive, and Computational Tools in OUD

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60

Code: NCT06136247·Recruiting

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International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia

for Hyponatremia Symptomatic

1 location in Pittsburgh

Sponsor: Rochester General Hospital

Sex: All·Age: 18+

Code: NCT07576036·Enrolling By Invitation

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for Metastatic Breast Cancer

36 locations incl. Scottsdale

Sponsor: LeonaBio

Sex: All·Age: 18+

Code: NCT05696626·Phase 3·Recruiting

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Study of Zimmer Biomet Mymobility Application on Reverse Total Shoulder Arthroplasty (RTSA) Outcomes

for Reverse Total Shoulder Arthroplasty

4 locations incl. Palm Beach Gardens

Sponsor: Campbell Clinic

Sex: All·Age: 18+

Code: NCT05789784·Enrolling By Invitation

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

for Cancer

15 locations incl. Los Angeles

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT05970497·Phase 1, Phase 2·Recruiting

Apply to this trial

Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders

for Eating Disorders

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 12 - 24

Code: NCT06085092·Recruiting

Apply to this trial

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting

Apply to this trial