Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Philadelphia, Pittsburgh +37 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting·Listed Apr 2025

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A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for Non Small Cell Lung Cancer

Sites in Hershey, Lancaster +42 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312137·Phase 3·Recruiting·Listed Mar 2024

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A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

for Psoriatic Arthritis

Drug: Zasocitinib

Sites in Wyomissing +51 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06671483·Phase 3·Recruiting·Listed Nov 2024

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ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for Autosomal Dominant Polycystic Kidney Disease

Sites in Philadelphia, Bethlehem +36 more locations

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18 - 55

Code: NCT06902558·Phase 2·Recruiting·Listed Mar 2025

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Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

for Peripheral Vascular Diseases

Sites in Philadelphia +37 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT04674969·Recruiting·Listed Dec 2020

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

Sites in Philadelphia +58 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819891·Phase 3·Recruiting·Listed Feb 2025

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A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

for Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)

Drug: Rituximab

Sites in Philadelphia +19 more locations

Sponsor: Pierre Fabre Medicament

Sex: All·Age: All ages

Code: NCT03394365·Phase 3·Recruiting·Listed Jan 2018

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Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for Extensive-stage Small-cell Lung Cancer

Sites in Fountain Hill +33 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712355·Phase 3·Recruiting·Listed Dec 2024

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A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

for Plaque Psoriasis

Drug: Deucravacitinib

Sites in Philadelphia +43 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 12 - 17

Code: NCT06979453·Phase 3·Recruiting·Listed May 2025

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Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for Mitral Valve Regurgitation

Sites in Pittsburgh, Harrisburg +65 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18+

Code: NCT03242642·Recruiting·Listed Aug 2017

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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

for Locally Advanced Pancreatic Cancer

Sites in Pittsburgh +14 more locations

Sponsor: RenovoRx

Sex: All·Age: 18+

Code: NCT03257033·Phase 3·Recruiting·Listed Aug 2017

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A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

for Metabolic Dysfunction-Associated SteatoHepatitis (MASH)

Sites in Philadelphia, Hershey +35 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT05519475·Phase 2·Recruiting·Listed Aug 2022

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RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

for Pain

Sites in Trevose +11 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01719055·Recruiting·Listed Nov 2012

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A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

Drug: Nerandomilast

Sites in Philadelphia, Pittsburgh +30 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting·Listed Feb 2025

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

Sites in Philadelphia, Pittsburgh +19 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting·Listed Jan 2020

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Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

for Acute Stroke

Sites in Philadelphia +35 more locations

Sponsor: DiaMedica Therapeutics Inc

Sex: All·Age: 18 - 90

Code: NCT05065216·Phase 2, Phase 3·Recruiting·Listed Oct 2021

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A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for Prostate Cancer

Sites in Philadelphia +49 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT06925737·Phase 3·Recruiting·Listed Apr 2025

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A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Philadelphia, Willow Grove +44 more locations

Sponsor: Celgene

Sex: Male·Age: 18+

Code: NCT06764485·Phase 3·Recruiting·Listed Jan 2025

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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sites in Duncansville +55 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06972446·Phase 2·Recruiting·Listed May 2025

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ACP-204 in Adults With Alzheimer's Disease Psychosis

for Alzheimer's Disease Psychosis

Sites in Abington +30 more locations

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 95

Code: NCT06159673·Phase 2, Phase 3·Recruiting·Listed Dec 2023

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

Sites in Media +58 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting·Listed Oct 2024

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Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Intermediate Risk Non-Muscle Invasive Bladder Cancer

Drug: Nadofaragene Firadenovec

Sites in Philadelphia, Pittsburgh +48 more locations

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06510374·Phase 3·Recruiting·Listed Jul 2024

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

Sites in Philadelphia +36 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting·Listed Apr 2025

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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

Sites in Philadelphia +34 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting·Listed Apr 2025

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FOG-001 in Locally Advanced or Metastatic Solid Tumors

for Cancer

Sites in Philadelphia, Pittsburgh +28 more locations

Sponsor: Parabilis Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05919264·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

for Chronic Migraine

Drug: Atogepant

Sites in Smithfield, Scottdale +26 more locations

Sponsor: AbbVie

Sex: All·Age: 12 - 17

Code: NCT06810505·Phase 3·Recruiting·Listed Feb 2025

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EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

Sites in Philadelphia, Upland +47 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting·Listed Aug 2024

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A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for Endometrial Adenocarcinoma

Sites in Pittsburgh +41 more locations

Sponsor: Acrivon Therapeutics

Sex: Female·Age: 18+

Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022

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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

for Type 2 Diabetes

Drug: Semaglutide

Sites in Scottdale +24 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06897475·Phase 2·Recruiting·Listed Mar 2025

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A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: riliprubart

Sites in Philadelphia, Hershey +31 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290141·Phase 3·Recruiting·Listed Mar 2024

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Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

Sites in Allentown +20 more locations

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting·Listed Aug 2024

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Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for Heart Failure With Preserved Ejection Fraction

Sites in Horsham +109 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07037459·Phase 3·Recruiting·Listed Jun 2025

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A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

for Solid Cancer

Sites in Philadelphia +24 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06161025·Phase 2, Phase 3·Recruiting·Listed Dec 2023

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

Sites in Pittsburgh +36 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting·Listed Mar 2025

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DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

Sites in Philadelphia, Pittsburgh +31 more locations

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting·Listed Jan 2023

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Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

for Advanced Solid Tumor

Sites in Philadelphia +23 more locations

Sponsor: Synthekine

Sex: All·Age: 18+

Code: NCT05098132·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

for Head and Neck Squamous Cell Carcinoma

Sites in Philadelphia, York +29 more locations

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06163534·Recruiting·Listed Dec 2023

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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for Hypertension

Sites in Philadelphia, Lancaster +31 more locations

Sponsor: SoniVie Inc.

Sex: All·Age: 22 - 75

Code: NCT06559891·Recruiting·Listed Aug 2024

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A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

for Primary Biliary Cholangitis (PBC)

Drug: Elafibranor

Sites in Pittsburgh +28 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT06016842·Phase 3·Recruiting·Listed Aug 2023

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SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

Sites in Philadelphia, Pittsburgh +41 more locations

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting·Listed Dec 2024

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