Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Amish/Mennonite Research Contact Registry

for All

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02990572·Recruiting·Listed Dec 2016

Apply to this trial

Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

for Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07167446·EARLY_Phase 1·Recruiting·Listed Sep 2025

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Parent Encouragement And Coaching of Happiness in Youth

for Depression

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 4 - 99·Accepts healthy volunteers

Code: NCT06725160·Recruiting·Listed Dec 2024

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Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

for Locally Advanced Hepatocellular Carcinoma

Drug: Atezolizumab

Sites in Pittsburgh +11 more locations

Sponsor: Academic and Community Cancer Research United

Sex: All·Age: 18+

Code: NCT05168163·Phase 2·Recruiting·Listed Dec 2021

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Identification of Critical Thermal Environments for Aged Adults

for Aging

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04284397·EARLY_Phase 1·Recruiting·Listed Feb 2020

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iLookOut for Child Abuse -Online Learning Module for Early Childcare Providers

for Child Abuse

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT02225301·Recruiting·Listed Aug 2014

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Longitudinal Study for Relapsing Polychondritis

for Relapsing Polychondritis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT04919538·Recruiting·Listed Jun 2021

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Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

for Anatomic Stage 0 Breast Cancer AJCC v8

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 40+

Code: NCT04959474·Recruiting·Listed Jul 2021

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The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

Sites in Philadelphia, Willow Grove & Abington

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05502523·Recruiting·Listed Aug 2022

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Longitudinal Study for Central Nervous System Vasculitis

for Central Nervous System Vasculitis

Sites in Philadelphia +3 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05734404·Recruiting·Listed Feb 2023

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[18F] F-GLN by PET/CT in Breast Cancer

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT03863457·Phase 1·Recruiting·Listed Mar 2019

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UPenn Observational Research Repository on Neurodegenerative Disease

for Frontotemporal Degeneration(FTD)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04715399·Recruiting·Listed Jan 2021

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Motivation for Daily Living Skills

for Autism Spectrum Disorder (ASD)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 16 - 25

Code: NCT07159308·Recruiting·Listed Sep 2025

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Development and Testing of imHere4U: A Digital Suicide Prevention Intervention for Cyberbullied Adolescents

for Psychological Distress

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 17

Code: NCT06002191·Recruiting·Listed Aug 2023

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Need to be Needed (N2BN) Intervention

for Loneliness

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 99

Code: NCT06510439·Recruiting·Listed Jul 2024

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PET Image in PAH Patients

for Pulmonary Arterial Hypertension

1 location in Pittsburgh

Sponsor: Stephen Y. Chan

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT05452889·EARLY_Phase 1·Recruiting·Listed Jul 2022

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Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

for Ascending Aortic Aneurysm Enlargement

Sites in Philadelphia +14 more locations

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18 - 79

Code: NCT03536312·Recruiting·Listed May 2018

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Longitudinal Tumor Burden Quantification Using Circulating Tumor DNA in Metastatic Lobular Breast Cancer

for Metastatic Invasive Lobular Carcinoma (mILC)

1 location in Pittsburgh

Sponsor: Julia Foldi

Sex: Female·Age: 18+

Code: NCT06666439·Recruiting·Listed Oct 2024

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APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

for Pre-Eclampsia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 45

Code: NCT06408181·Phase 3·Recruiting·Listed May 2024

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Naltrexone in AUD Reward Drinkers

for Alcohol Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65

Code: NCT05028062·Phase 4·Recruiting·Listed Aug 2021

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Music Listening: A Mechanistic Trial

for Critical Illness

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 2 Months - 17

Code: NCT05541029·Recruiting·Listed Sep 2022

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AWARE: Management of ADHD in Autism Spectrum Disorder

for ADHD

Sites in Philadelphia, Pittsburgh +8 more locations

Sponsor: Daniel Coury

Sex: All·Age: 4 - 17

Code: NCT05916339·Phase 4·Recruiting·Listed Jun 2023

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Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

Sites in Philadelphia +21 more locations

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting·Listed Dec 2025

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ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

for Mycosis Fungoides

Sites in Pittsburgh +6 more locations

Sponsor: Stanford University

Sex: All·Age: All ages

Code: NCT02848274·Recruiting·Listed Jul 2016

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Neurophysiologic Biomarkers in Rett Syndrome

for Rett Syndrome

Sites in Philadelphia +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: Female·Age: 1 - 18·Accepts healthy volunteers

Code: NCT05932589·Recruiting·Listed Jul 2023

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Evaluation of Outcome Metrics in Alexander Disease

for Alexander Disease

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02714764·Recruiting·Listed Mar 2016

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Beta-cell Response to Incretin Hormones in Cystic Fibrosis

for Cystic Fibrosis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01851694·Recruiting·Listed May 2013

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Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

for Early Stage Non-Small Cell Lung Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT03546829·Phase 1·Recruiting·Listed Jun 2018

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Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

for Idiopathic Pulmonary Fibrosis

2 locations in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 18 - 60

Code: NCT03500731·Phase 1, Phase 2·Recruiting·Listed Apr 2018

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Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

for Primary Immunodeficiency (PID)

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 2 Months - 60

Code: NCT04528355·Recruiting·Listed Aug 2020

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A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Sites in Philadelphia +16 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04375033·Phase 4·Recruiting·Listed May 2020

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Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction

for Squamous Cell Carcinoma

1 location in Pittsburgh

Sponsor: Matthew Spector

Sex: All·Age: 18+

Code: NCT06831149·Phase 2·Recruiting·Listed Feb 2025

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Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

for Ischemic Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 90

Code: NCT04897334·Recruiting·Listed May 2021

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Bright Light Therapy for OSA

for Obstructive Sleep Apnea

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 65

Code: NCT05917119·Recruiting·Listed Jun 2023

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Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF)

for Cystic Fibrosis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05998629·Recruiting·Listed Aug 2023

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Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

for Osteoarthritis, Knee

Sites in Philadelphia +4 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 90

Code: NCT06488144·Phase 3·Recruiting·Listed Jul 2024

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Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression

for Cardiac Sarcoidosis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06510894·Recruiting·Listed Jul 2024

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A Vaccine Trial for Low Grade Gliomas

for Low Grade Glioma

1 location in Pittsburgh

Sponsor: James Felker

Sex: All·Age: 12 Months - 21

Code: NCT02358187·Phase 2·Recruiting·Listed Feb 2015

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Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

for Lung Cancer, Nonsmall Cell

Drug: Atezolizumab

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04691817·Phase 1, Phase 2·Recruiting·Listed Dec 2020

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Resting State Changes Following Theta Burst Stimulation

for Brain Connectivity

1 location in Philadelphia

Sponsor: Nicholas Balderston, PhD

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05322239·Recruiting·Listed Apr 2022

Apply to this trial