Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 10, 2026.

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3,657 clinical trials

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

174 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

for Advanced or Metastatic Solid Tumors

11 locations incl. Scottsdale

Sponsor: Incendia Therapeutics

Sex: All·Age: 18+

Code: NCT05753722·Phase 1·Recruiting

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The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study

for Venous Thromboses

27 locations incl. Stanford

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05489588·Recruiting

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FTT PET/CT in Metastatic Prostate Cancer

for Prostate Cancer Metastatic

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Male·Age: 18+

Code: NCT05242744·Recruiting

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A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for Adenocarcinoma of Lung

6 locations incl. Beverly Hills

Sponsor: Lantern Pharma Inc.

Sex: All·Age: 18+

Code: NCT05456256·Phase 2·Recruiting

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Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for Thyroid Cancer

6 locations incl. Washington D.C.

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT05668962·Phase 2·Recruiting

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Longitudinal Study for Central Nervous System Vasculitis

for Central Nervous System Vasculitis

4 locations incl. Rochester

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05734404·Recruiting

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HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

for Heart Failure

6 locations incl. Sacramento

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT05873634·Recruiting

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A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for Areata Alopecia

Drug: Baricitinib

44 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT05723198·Phase 3·Recruiting

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Collection of Circulating Biomarkers in Pancreatic Cancer

for Pancreas Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05743049·Recruiting

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Effect of Raised End-Tidal pCo2 on Choroidal Volume

for Intraocular Pressure

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 8·Accepts healthy volunteers

Code: NCT06275308·Recruiting

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

9 locations incl. Phoenix

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

3 locations incl. Duarte

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting

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An Extension Study of JR-141 to Evaluate the Long-term Safety and Efficacy in MPS II (Hunter Syndrome) Subjects

for Mucopolysaccharidosis II

2 locations incl. Oakland

Sponsor: JCR Pharmaceuticals Co., Ltd.

Sex: All·Age: All ages

Code: NCT05594992·Phase 3·Enrolling By Invitation

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma

13 locations incl. San Francisco

Sponsor: K36 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05651932·Phase 1·Recruiting

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Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

for Lung Cancer

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05800587·Phase 2·Recruiting

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Decoding and Modulating Affective Brain States

for Rumination

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65

Code: NCT05437705·Recruiting

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

30 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting

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Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

for Ductus Arteriosus, Patent

24 locations incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 7 Days - 32 Days

Code: NCT05547165·Recruiting

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

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Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods

for Obesity

1 location in Philadelphia

Sponsor: Oregon Research Institute

Sex: All·Age: 18 - 65

Code: NCT05437809·Recruiting

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Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C

for Irritable Bowel Syndrome With Constipation (IBS-C)

Drug: Tenapanor

27 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 6 - 18

Code: NCT05905926·Phase 3·Enrolling By Invitation

Improve Outcomes for Older Allogeneic Transplant Recipients

for Allogeneic Transplantation

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 60+

Code: NCT05612789·Recruiting

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A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer

for HR+/HER2-negative Breast Cancer

9 locations incl. Chicago

Sponsor: Totus Medicines

Sex: Female·Age: 18+

Code: NCT05683418·Phase 1·Recruiting

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3D-Printed Versus Laboratory-Fabricated Hyrax Expanders

for Maxillary Expansion

2 locations incl. Pittsburgh

Sponsor: Ildeu Andrade Jr.

Sex: All·Age: 8 - 13·Accepts healthy volunteers

Code: NCT05743127·Recruiting

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Cortical Contributions to FFR: Post-Op Outcomes

for Language

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13 - 25

Code: NCT05214092·Enrolling By Invitation

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT

for Head and Neck Cancer

5 locations incl. Detroit

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05442957·Recruiting

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A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

for Primary Generalized Tonic-Clonic Seizures

59 locations incl. Mobile

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05667142·Phase 3·Recruiting

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Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma

for Merkel Cell Carcinoma

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05496036·Phase 2·Recruiting

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Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

for Heterozygous or Homozygous Familial Hypercholesterolemia

Drug: Inclisiran

5 locations incl. Boca Raton

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT05682378·Phase 3·Recruiting

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A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

for Metabolic Dysfunction-Associated SteatoHepatitis (MASH)

61 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT05519475·Phase 2·Recruiting

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Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype

for Obstructive Sleep Apnea

2 locations incl. Columbus

Sponsor: Ohio State University

Sex: All·Age: 18 - 75

Code: NCT05742360·Recruiting

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Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

for Surgery

6 locations incl. Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05722002·Phase 4·Recruiting

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PUSH-IT Continuing Enteral Feeds for Tracheostomy

for Tracheostomy Complication

6 locations incl. Danbury

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+

Code: NCT05906472·Recruiting

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Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

for Advanced Lung Neuroendocrine Tumor

29 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04665739·Phase 2·Recruiting

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Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

10 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting

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A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

for Adult Growth Hormone Deficiency

29 locations incl. Phoenix

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05718570·Enrolling By Invitation

EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

for Cancer

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 20 - 89

Code: NCT06083324·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations

for Prostate Cancer

6 locations incl. La Jolla

Sponsor: Rana McKay, MD

Sex: Male·Age: 18+

Code: NCT05498272·Phase 2·Recruiting

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