Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 11, 2026.

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3,655 clinical trials

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

Apply to this trial

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation

A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

for Oligometastatic Breast Carcinoma

8 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05534438·Phase 2·Recruiting

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Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis

for Acute Pancreatitis

3 locations incl. Birmingham

Sponsor: Erasmus Medical Center

Sex: All·Age: 18+

Code: NCT04814693·Enrolling By Invitation

TVMR With the INNOVALVE System Trial - Early Feasibility Study

for Mitral Valve Regurgitation (Degenerative or Functional)

20 locations incl. Los Angeles

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04919980·Recruiting

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Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation

for Ventricular Tachycardia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05377216·EARLY_Phase 1·Recruiting

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SBRT With Atezo/Bev for HCC

for Hepatocellular Carcinoma

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18 - 99

Code: NCT05488522·Phase 1·Recruiting

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Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV

for HIV Infections

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 80

Code: NCT05502653·Recruiting

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Improving Efficacy of Voice Therapy Concepts Via Telepractice and Mobile App Technology

for Voice Disorders

1 location in West Chester

Sponsor: West Chester University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05220982·Recruiting

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Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for Platinum-resistant Ovarian Cancer

Drug: Bevacizumab

31 locations incl. Mobile

Sponsor: Genelux Corporation

Sex: Female·Age: 18+

Code: NCT05281471·Phase 3·Recruiting

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The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

4 locations incl. Abington

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05502523·Recruiting

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NASH AMPK Exercise Dosing (AMPED) Trial

for NAFLD

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 69

Code: NCT04987879·Recruiting

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Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears

for Rotator Cuff Injuries

8 locations incl. Rome

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 18+

Code: NCT05444465·Recruiting

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Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

for Advanced Alveolar Soft Part Sarcoma

Drug: Atezolizumab

13 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05333458·Phase 2·Recruiting

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A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for Endometrial Adenocarcinoma

69 locations incl. Mobile

Sponsor: Acrivon Therapeutics

Sex: Female·Age: 18+

Code: NCT05548296·Phase 2·Recruiting

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Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

for HR+/HER2-negative Breast Cancer

10 locations incl. Loma Linda

Sponsor: SynDevRx, Inc.

Sex: All·Age: 18+

Code: NCT05455619·Phase 1, Phase 2·Recruiting

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A Prospective Sub-Study of the Global Hypophosphatasia Registry

for Hypophosphatasia

12 locations incl. Hartford

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT05234567·Recruiting

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A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery

for Coagulation Disorder

13 locations incl. Arkansas City

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT05156983·Phase 3·Recruiting

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A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum

for Suicidal Ideation

5 locations incl. Baltimore

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 12 - 99

Code: NCT05398250·Enrolling By Invitation

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

58 locations incl. Homewood

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05511363·Phase 3·Recruiting

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Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial

for Pneumonia

14 locations incl. Phoenix

Sponsor: University of Utah

Sex: All·Age: Up to 18

Code: NCT05471908·Recruiting

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Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials

for Dermatitis Atopic

Drug: Amlitelimab

96 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT05492578·Phase 2, Phase 3·Enrolling By Invitation

A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007

for T-cell Acute Lymphoblastic Leukemia

4 locations incl. Duarte

Sponsor: Wugen, Inc.

Sex: All·Age: 12+

Code: NCT05509855·Enrolling By Invitation

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes

for Open Angle Glaucoma

15 locations incl. Newport Beach

Sponsor: Iantrek, Inc.

Sex: All·Age: 21+

Code: NCT05506423·Enrolling By Invitation

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for Obstructive Hypertrophic Cardiomyopathy

Drug: Mavacamten

62 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05489705·Recruiting

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MiSight 1 Day Safety Post-Approval Study

for Myopia

47 locations incl. Gilbert

Sponsor: CooperVision, Inc.

Sex: All·Age: 8 - 12·Accepts healthy volunteers

Code: NCT05285527·Recruiting

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A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

for Lymphoma, Non-Hodgkin

14 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05421663·Phase 1, Phase 2·Recruiting

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International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery

for Congenital Disorders

4 locations incl. New York

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 60 Weeks

Code: NCT05673499·Recruiting

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LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study

for LCAT Deficiency

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT06217588·Recruiting

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Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

for Anal Melanoma

Drug: Cabozantinib

143 locations incl. Auburn

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05111574·Phase 2·Recruiting

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

51 locations incl. Mobile

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting

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Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

for Lupus Nephritis

26 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05268289·Phase 2·Recruiting

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Arrhythmia Detection After MI

for Acute Myocardial Infarction

1 location in Pittsburgh

Sponsor: Samir Saba

Sex: All·Age: 18+

Code: NCT05073419·Recruiting

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Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

for Child

11 locations incl. Madera

Sponsor: Johns Hopkins University

Sex: All·Age: Up to 18

Code: NCT04989790·Recruiting

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Pediatric Dose Optimization for Seizures in Emergency Medical Services

for Seizures

20 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: 6 Months - 13

Code: NCT05121324·Phase 3·Recruiting

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Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

for Cardiac Arrest, Out-Of-Hospital

50 locations incl. Birmingham

Sponsor: University of Michigan

Sex: All·Age: 2 Days - 17

Code: NCT05376267·Recruiting

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

165 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting

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The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

for Extubation Failure

17 locations incl. Little Rock

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 9 Weeks

Code: NCT05446272·Recruiting

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First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors

for Gastrointestinal Neoplasms

8 locations incl. Miami

Sponsor: IDRX, Inc., a wholly owned subsidiary of GSK, LLC

Sex: All·Age: 18+

Code: NCT05489237·Phase 1·Recruiting

Apply to this trial