Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 11, 2026.

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3,655 clinical trials

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Rett Syndrome Registry

for Rett Syndrome

18 locations incl. Birmingham

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting

Apply to this trial

Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

for Elevated Serum PSA

3 locations incl. Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18 - 80

Code: NCT05512754·Phase 4·Recruiting

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A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

for Cancer

7 locations incl. Monterey

Sponsor: N-Power Medicine

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT06877884·Recruiting

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Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF

for Idiopathic Pulmonary Fibrosis

20 locations incl. Mesa

Sponsor: Daewoong Pharmaceutical Co. LTD.

Sex: All·Age: 40+

Code: NCT05389215·Phase 2·Recruiting

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Neoadjuvant Breast Cancer Time Restricted Eating

for Anatomic Stage I Breast Cancer AJCC v8

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05327608·Recruiting

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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

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A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

19 locations incl. Anaheim

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05254743·Phase 3·Recruiting

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Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

for Breast Cancer

4 locations incl. Chicago

Sponsor: Ruth O'Regan

Sex: All·Age: 18+

Code: NCT04886531·Phase 2·Recruiting

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A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)

for Mucopolysaccharidosis II

8 locations incl. Oakland

Sponsor: Denali Therapeutics Inc.

Sex: All·Age: 2 - 25

Code: NCT05371613·Phase 2, Phase 3·Recruiting

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A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

11 locations incl. Phoenix

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2 - 17

Code: NCT05265273·Phase 2, Phase 3·Recruiting

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A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

for Unresectable Melanoma

10 locations incl. Los Angeles

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05361174·Phase 1, Phase 2·Recruiting

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Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

for Oropharynx Cancer

1 location in Pittsburgh

Sponsor: Heath Skinner

Sex: All·Age: 18+

Code: NCT05388773·Phase 2·Recruiting

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Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding

for Epilepsy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18 - 45

Code: NCT05450978·Recruiting

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Providing Oxygen During Intubation in the NICU Trial

for Neonatal Respiratory Failure

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 365 Days

Code: NCT05451953·Recruiting

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Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI

for Posttraumatic Headache

4 locations incl. Fort Bragg

Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

Sex: All·Age: 18 - 50

Code: NCT05049057·Phase 2·Recruiting

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Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

for Small-cell Lung Cancer

Drug: Onvansertib

2 locations incl. Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05450965·Phase 2·Recruiting

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Caregiver Stress and Sleep Study

for Depressive Symptoms

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT05219955·Recruiting

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Diabetes Clinical Decision Support

for Hyperglycemia

2 locations incl. Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT05447806·Recruiting

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Otoferlin Gene-mediated Hearing Loss Natural History Study

for Sensorineural Hearing Loss, Bilateral

4 locations incl. Iowa City

Sponsor: Akouos, Inc.

Sex: All·Age: Up to 44

Code: NCT05572073·Recruiting

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Testing the Safety and Efficacy of the Addition of a New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Cisplatin and Etoposide or Carboplatin and Paclitaxel) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma

for Advanced NUT Carcinoma

5 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05019716·Phase 1, Phase 2·Recruiting

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Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

for Myelofibrosis

2 locations incl. Philadelphia

Sponsor: Karen Ballen, MD

Sex: All·Age: 18 - 75

Code: NCT05233618·Phase 1·Recruiting

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TEMPUS Small Cell Lung Cancer OBSERVATIONAL STUDY (Sculptor)

for Small Cell Lung Cancer

11 locations incl. Los Alamitos

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05257551·Recruiting

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A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

for LGLL - Large Granular Lymphocytic Leukemia

15 locations incl. Birmingham

Sponsor: Dren Bio

Sex: All·Age: 18+

Code: NCT05475925·Phase 1, Phase 2·Recruiting

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ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study

for Age Related Macular Degeneration (AMD)

22 locations incl. Poway

Sponsor: Gyroscope Therapeutics Limited

Sex: All·Age: 55+

Code: NCT05481827·Phase 2·Enrolling By Invitation

A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Scottsdale

Sponsor: Peel Therapeutics Inc

Sex: All·Age: 18+

Code: NCT05329103·Phase 1·Recruiting

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PET Image in PAH Patients

for Pulmonary Arterial Hypertension

1 location in Pittsburgh

Sponsor: Stephen Y. Chan

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT05452889·EARLY_Phase 1·Recruiting

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

1021 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting

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Study of INCB123667 in Subjects With Advanced Solid Tumors

for Solid Tumors

Drug: INCB123667

19 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05238922·Phase 1·Recruiting

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PDN Post Market, Multicenter, Prospective, Global Clinical Study

for Diabetic Neuropathy, Painful

8 locations incl. Anchorage

Sponsor: Nevro Corp

Sex: All·Age: 18+

Code: NCT05301816·Recruiting

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Abatacept in Immune Checkpoint Inhibitor Myocarditis

for Myocarditis Acute

29 locations incl. Los Angeles

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05335928·Phase 3·Recruiting

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Children's Bipolar Network Treatment Trial I

for Bipolar Disorder

4 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 9 - 19

Code: NCT05427123·Recruiting

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Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

for Advanced Extrapulmonary Neuroendocrine Carcinoma

Drug: Atezolizumab

248 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05058651·Phase 2, Phase 3·Recruiting

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Ultrafiltration Versus IV Diuretics in Worsening Heart Failure

for Heart Failure (for Example, Fluid Overload)

17 locations incl. Tucson

Sponsor: Nuwellis, Inc.

Sex: All·Age: 18+

Code: NCT05318105·Recruiting

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Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

for Gastric Cancer

3 locations incl. Palo Alto

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT05274048·Phase 1·Recruiting

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Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD

for Neuromyelitis Optica Spectrum Disorder

6 locations incl. Washington D.C.

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT05346354·Phase 2, Phase 3·Recruiting

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GEMINI-NSCLC: NSCLC Biomarker Study

for Non-Small Cell Lung Cancer

58 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05236114·Recruiting

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Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

for Colorectal Cancer

20 locations incl. Fort Smith

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05234177·Recruiting

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

45 locations incl. Birmingham

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05338697·Recruiting

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Ferric Citrate and Chronic Kidney Disease in Children

for Chronic Kidney Diseases

18 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 6 - 18

Code: NCT04741646·Phase 2·Recruiting

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A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

for B-Cell Non-Hodgkin Lymphoma

25 locations incl. Clovis

Sponsor: ADC Therapeutics S.A.

Sex: All·Age: 18+

Code: NCT04970901·Phase 1·Recruiting

Apply to this trial