Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

for Gestational Diabetes

Sites in Philadelphia +1 more location

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419803·Recruiting·Listed May 2024

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The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.

for Nutraceuticals

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06274385·Recruiting·Listed Feb 2024

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Peer Facilitated Waitlist Controlled Transportation Study

for Serious Mental Illness

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 65

Code: NCT06370767·Recruiting·Listed Apr 2024

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Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for Thyroid Cancer

Sites in Philadelphia +5 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT05668962·Phase 2·Recruiting·Listed Dec 2022

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Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

for Prostate Cancer

Sites in Hershey +2 more locations

Sponsor: Albany Medical College

Sex: Male·Age: 18 - 80

Code: NCT05629494·Phase 4·Recruiting·Listed Nov 2022

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Pilot Trial of the RUBI Program for Autistic Adults

for Autism Spectrum Disorder

Sites in Philadelphia +2 more locations

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18+

Code: NCT06593613·Recruiting·Listed Sep 2024

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Biomechanical Footwear as a Non-invasive Alternative and Supplement to Total Knee Replacement

for Osteoarthritis, Knee

Sites in Danville & Wilkes-Barre

Sponsor: Geisinger Clinic

Sex: All·Age: 45 - 80

Code: NCT04732962·Recruiting·Listed Feb 2021

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Use of an Intrauterine Manipulator and Its Correlation with Positive Peritoneal Cytology in Early Stage Endometrial Cancers

for Endometrial Cancer

1 location in York

Sponsor: WellSpan Health

Sex: Female·Age: 18+

Code: NCT04570553·Recruiting·Listed Sep 2020

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International CDKL5 Clinical Research Network

for CDKL5

Sites in Philadelphia +7 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 1 Month - 100

Code: NCT05558371·Recruiting·Listed Sep 2022

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COVID-19 Vaccines Safety Tracking (CoVaST)

for Adverse Reaction to Vaccine

1 location in Philadelphia

Sponsor: Masaryk University

Sex: All·Age: 18+

Code: NCT04834869·Recruiting·Listed Apr 2021

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Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging

for Healthy

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04275453·Phase 1, Phase 2·Recruiting·Listed Feb 2020

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Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates

for Schizophrenia

1 location in Philadelphia

Sponsor: Corporal Michael J. Crescenz VA Medical Center

Sex: All·Age: 18 - 75

Code: NCT03495024·Phase 4·Recruiting·Listed Apr 2018

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A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy (DCM)

Sites in Philadelphia +27 more locations

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07771465·Phase 3·Recruiting·Listed Aug 18, 2026

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Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients

for Malnutitrion

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07776704·Recruiting·Listed Aug 20, 2026

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Evaluation of Filler Injection for Chin Profile Enhancement

for Chin Regression

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 22 - 55·Accepts healthy volunteers

Code: NCT07777926·Phase 4·Recruiting·Listed Aug 20, 2026

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Imaging Mitochondrial Complex-I in Cocaine Use Disorder: a [F-18]BCPP-EF PET Study

for Cocaine Use Disorder

1 location in Pittsburgh

Sponsor: Rajesh Narendran

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07773649·EARLY_Phase 1·Recruiting·Listed Aug 19, 2026

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Phase 3 Study to Assess Efficacy, Safety & Tolerability of OCU410 For Geographic Atrophy Secondary to Dry AMD

for Dry Age-related Macular Degeneration

Sites in Erie +2 more locations

Sponsor: Ocugen

Sex: All·Age: 55+

Code: NCT07770828·Phase 3·Recruiting·Listed Aug 18, 2026

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Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

for Overweight

Drug: Semaglutide

Sites in Philadelphia +15 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07770841·Phase 3·Recruiting·Listed Aug 18, 2026

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The Appendix Cancer PMP Research Foundation Natural History Study/Patient Registry

for Appendix Cancer

1 location in Springfield

Sponsor: Appendix Cancer Pseudomyxoma Peritonei Research Foundation

Sex: All·Age: All ages

Code: NCT07769346·Recruiting·Listed Aug 17, 2026

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A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

for Type 2 Diabetes

Drug: Survodutide

Sites in Pittsburgh, Uniontown +87 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07754461·Phase 3·Recruiting·Listed Aug 10, 2026

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The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms

for Posttraumatic Stress Disorder (PTSD)

1 location in Coatesville

Sponsor: Coatesville VA Medical Center

Sex: All·Age: 18+

Code: NCT07756723·Phase 2, Phase 3·Recruiting·Listed Aug 11, 2026

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Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

for Castration-Resistant Prostate Cancer (CRPC)

Drug: Apalutamide

Sites in Lancaster +13 more locations

Sponsor: Monte Rosa Therapeutics, Inc

Sex: Male·Age: 18+

Code: NCT07745361·Phase 2·Recruiting·Listed Aug 4, 2026

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A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

for Obesity

Sites in Philadelphia, Pittsburgh +83 more locations

Sponsor: Ascletis Pharma (China) Co., Limited

Sex: All·Age: 18+

Code: NCT07743450·Phase 3·Recruiting·Listed Aug 3, 2026

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A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

for Obesity

Sites in Philadelphia, Pittsburgh +65 more locations

Sponsor: Ascletis Pharma (China) Co., Limited

Sex: All·Age: 18+

Code: NCT07743463·Phase 3·Recruiting·Listed Aug 3, 2026

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A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia Areata

for Alopecia Areata

Drug: Ritlecitinib

Sites in Plymouth Meeting +15 more locations

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT07733765·Phase 3·Recruiting·Listed Jul 29, 2026

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EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer

for Cancer

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female·Age: 20 - 89

Code: NCT07739563·Recruiting·Listed Jul 31, 2026

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Pemefolacianine for IMI of Lung Cancer

for Lung Cancer (Locally Advanced or Metastatic)

1 location in Philadelphia

Sponsor: Sunil Singhal

Sex: All·Age: 18+

Code: NCT07772895·Phase 1·Recruiting·Listed Aug 19, 2026

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An Observational Study of Patients With Dermatologic Disease

for Vitiligo

Sites in Philadelphia +2 more locations

Sponsor: Target PharmaSolutions, Inc.

Sex: All·Age: All ages

Code: NCT07748169·Recruiting·Listed Aug 5, 2026

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Tai Chi for Reducing Aromatase Inhibitor-Induced Arthralgia

for Hormone Receptor Positive Breast Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT07737951·Recruiting·Listed Jul 30, 2026

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A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)

for Short Bowel Syndrome (SBS)

Sites in Philadelphia +16 more locations

Sponsor: VectivBio AG

Sex: All·Age: 18+

Code: NCT07742735·Phase 3·Recruiting·Listed Aug 3, 2026

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A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis

for Chronic Obstructive Pulmonary Disease With Chronic Bronchitis

Sites in DuBois +2 more locations

Sponsor: UCB Biopharma SRL

Sex: All·Age: 40 - 80

Code: NCT07725939·Phase 2·Recruiting·Listed Jul 24, 2026

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Observational Approach Versus Surgical Intervention for Stones

for Nephrolithiasis

Sites in Philadelphia +1 more location

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 6+

Code: NCT07718802·Recruiting·Listed Jul 22, 2026

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A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Sites in DuBois +2 more locations

Sponsor: UCB Biopharma SRL

Sex: All·Age: 18 - 80

Code: NCT07720375·Phase 2·Recruiting·Listed Jul 22, 2026

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Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

for Respiratory Syncytial Virus Immunization

Sites in Philadelphia +16 more locations

Sponsor: Sanofi

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07734649·Phase 1, Phase 2·Recruiting·Listed Jul 29, 2026

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Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit

for Midface Volume Deficit

Sites in Bryn Mawr +4 more locations

Sponsor: Helios Aesthetics Inc.

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07710443·Recruiting·Listed Jul 17, 2026

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Dorsal Root Electrical Stimulation in Children With Cerebral Palsy

for Cerebral Palsy (CP)

1 location in Pittsburgh

Sponsor: Martin Piazza

Sex: All·Age: 3 - 14

Code: NCT07715006·Recruiting·Listed Jul 20, 2026

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Caregiver-Adolescent Dating Violence Prevention Intervention Pilot Trial

for Adolescent Relationship Abuse

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT07718022·Recruiting·Listed Jul 21, 2026

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DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention

for Preterm Birth

2 locations in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07698483·Recruiting·Listed Jul 13, 2026

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Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for Obesity

Sites in Newport +69 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07684235·Phase 3·Recruiting·Listed Jul 2026

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A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus

for Cutaneous Lupus Erythematosus (CLE)

1 location in Philadelphia

Sponsor: Victoria Werth

Sex: All·Age: 18+

Code: NCT07694336·Phase 2·Recruiting·Listed Jul 2026

Apply to this trial