Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 11, 2026.

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3,655 clinical trials

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A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

for DLBCL

26 locations incl. Glendale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT05139017·Phase 2, Phase 3·Recruiting

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Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

for Glioma

10 locations incl. Hartford

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05188508·Phase 2·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT05197920·Recruiting

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A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

for Survivorship

3 locations incl. Miami

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05215353·Phase 4·Recruiting

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Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for Migraine

Drug: Ubrogepant

125 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05125302·Phase 3·Recruiting

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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

for AMD

107 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50 - 89

Code: NCT05407636·Phase 3·Recruiting

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Myriad™ Augmented Soft Tissue Reconstruction Registry

for Abdominal Wound Dehiscence

13 locations incl. Los Angeles

Sponsor: Aroa Biosurgery Limited

Sex: All·Age: 18+

Code: NCT05243966·Recruiting

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Insomnia Behavioral Intervention Study

for Chronic Insomnia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 55 - 85

Code: NCT05301543·Recruiting

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International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

for Kidney Cancer

7 locations incl. Los Angeles

Sponsor: Azienda Ospedaliero-Universitaria Careggi

Sex: All·Age: 18+

Code: NCT05363657·Recruiting

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Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

for Chronic Pancreatitis

3 locations incl. Indianapolis

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04996628·Recruiting

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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for Refractory Angina

70 locations incl. Phoenix

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT05102019·Recruiting

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

20 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting

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Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

for Alzheimer Disease, Late Onset

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 65 - 85·Accepts healthy volunteers

Code: NCT05138848·EARLY_Phase 1·Recruiting

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Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

for Cirrhosis, Liver

9 locations incl. Chandler

Sponsor: PharmaIN

Sex: All·Age: 18 - 75

Code: NCT05490888·Phase 1·Recruiting

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Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding

for GastroIntestinal Bleeding

1 location in Scranton

Sponsor: Xingshun Qi

Sex: All·Age: 18+

Code: NCT04662918·Recruiting

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Endometriosis and Microvascular Dysfunction: Role of Inflammation

for Endometriosis

1 location in University Park

Sponsor: Penn State University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05069740·EARLY_Phase 1·Recruiting

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The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease

for Dry Eye Syndromes

1 location in Pittsburgh

Sponsor: Rinsada

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07618364·Recruiting

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Primary Sclerosing Cholangitis in Children

for Primary Sclerosing Cholangitis

11 locations incl. Los Angeles

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 2 - 25

Code: NCT04181138·Recruiting

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Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

for Myeloid Leukemia, Philadelphia Positive

8 locations incl. Indianapolis

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 1 - 17

Code: NCT04925479·Phase 1, Phase 2·Recruiting

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Triage Survey for Psychiatry Research Eligibility

for Major Depressive Disorder

6 locations incl. Boston

Sponsor: Adams Clinical

Sex: All·Age: 18+

Code: NCT05800925·Recruiting

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Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD

for Neovascular Age-Related Macular Degeneration (nAMD)

16 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: All ages

Code: NCT05210803·Enrolling By Invitation

Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells

for Solid and Hematological Malignancies

49 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: All ages

Code: NCT05041309·Enrolling By Invitation

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

for Neovascular Age-related Macular Degeneration

Drug: Ranibizumab

50 locations incl. Mesa

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT04853251·Phase 4·Recruiting

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Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

for Renal Cell Carcinoma (RCC)

46 locations incl. Phoenix

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05176483·Phase 1·Recruiting

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

10 locations incl. Los Angeles

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting

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JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

for Carcinoma, Squamous Cell

26 locations incl. Birmingham

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 60+

Code: NCT04892173·Phase 3·Recruiting

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Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for Relapsed or Refractory T Cell Lymphoma

20 locations incl. Birmingham

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT05079282·Phase 1·Recruiting

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4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

for Neovascular (Wet) Age-Related Macular Degeneration

24 locations incl. Phoenix

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT05197270·Phase 1, Phase 2·Recruiting

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A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

for Stereotypical Prolonged Seizures

66 locations incl. Phoenix

Sponsor: UCB Biopharma SRL

Sex: All·Age: 12+

Code: NCT05077904·Phase 3·Recruiting

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Cognitive and Affective Mechanisms Underlying an Olfactory Approach to Modify Cigarette Craving

for Craving

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 49

Code: NCT04902469·Recruiting

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Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)

for Atrial Fibrillation (AF)

4 locations incl. Evanston

Sponsor: McMaster University

Sex: All·Age: 18 - 100

Code: NCT06844227·Recruiting

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Pediatric Post-Approval Registry

for Obstructive Sleep Apnea

8 locations incl. Aurora

Sponsor: Inspire Medical Systems, Inc.

Sex: All·Age: 18 - 21

Code: NCT04457154·Recruiting

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

14 locations incl. Palo Alto

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05125016·Phase 1, Phase 2·Recruiting

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Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

for Melanoma

2 locations incl. Chicago

Sponsor: Yana Najjar

Sex: All·Age: 18+

Code: NCT04572451·Phase 1·Recruiting

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SKIP for PA Study: Team and Leadership Level Implementation Support for Collaborative Care

for Child Behavior Problem

2 locations incl. Philadelphia

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04946253·Recruiting

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GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study

for Pelvic Organ Prolapse

2 locations incl. North Wales

Sponsor: Ethicon, Inc.

Sex: Female·Age: 21+

Code: NCT04829058·Recruiting

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HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

for Hip Fractures

19 locations incl. Chandler

Sponsor: Population Health Research Institute

Sex: All·Age: 45+

Code: NCT04743765·Recruiting

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Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

for Parkinson's Disease

2 locations incl. Omaha

Sponsor: University of Nebraska

Sex: All·Age: 18 - 80

Code: NCT05070013·Recruiting

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Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

for Hemophilia A

4 locations incl. Iowa City

Sponsor: Pfizer

Sex: Male·Age: 1 - 74

Code: NCT05145127·Phase 3·Recruiting

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Knee Related Subchondral Bone Lesions Treated With IOBP

for Subchondral Cyst

5 locations incl. Denver

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 60

Code: NCT05314608·Recruiting

Apply to this trial