Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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Interpersonal Communication Training and Vaccination Workflow Training Alone and in Combination to Improve Communication and Recommendations About HPV Vaccination in Pharmacies, IMPACT HPV Trial

for Human Papillomavirus-Related Carcinoma

Sites in University Park +1 more location

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06926062·Recruiting·Listed Apr 2025

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

Sites in Philadelphia, West Chester +175 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting·Listed Nov 2024

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Pediatric Percutaneous Ultrasound Gastrostomy Technique

for Gastrostomy

Sites in Philadelphia +2 more locations

Sponsor: CoapTech

Sex: All·Age: 0 - 21

Code: NCT05966311·Recruiting·Listed Jul 2023

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Real-world Study of Treatment Outcomes in Chronic Inflammatory Demyelinating Polyneuropathy/Polyradiculoneuropathy (CIDP)

for Polyneuropathy, Inflammatory Demyelinating, Chronic

1 location in Swiftwater

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06968975·Recruiting·Listed May 2025

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Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

for Pulmonary Arterial Hypertension

Sites in Philadelphia, Pittsburgh +27 more locations

Sponsor: Gossamer Bio USA, Inc.

Sex: All·Age: 18 - 75

Code: NCT06274801·Phase 3·Recruiting·Listed Feb 2024

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Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

for Binge-Eating Disorder

Drug: Solriamfetol

Sites in Allentown, Media +36 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 55

Code: NCT06413433·Phase 3·Recruiting·Listed May 2024

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

Sites in Philadelphia, Upland +66 more locations

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting·Listed Feb 2025

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Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

for Excessive Sleepiness

Drug: Solriamfetol

Sites in Wyomissing +40 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06568367·Phase 3·Recruiting·Listed Aug 2024

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Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

for Burns

2 locations in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06857435·Recruiting·Listed Mar 2025

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Autologous Point-of-Care Adipose Therapy: Recent Injury

for Burns

2 locations in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06857448·Recruiting·Listed Mar 2025

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

Sites in Philadelphia, Smithfield +28 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting·Listed Apr 2025

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Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Philadelphia +7 more locations

Sponsor: MOMA Therapeutics

Sex: All·Age: 18+

Code: NCT06545942·Phase 1·Recruiting·Listed Aug 2024

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

Sites in Pittsburgh +49 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting·Listed Jan 2025

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Ketones for Opioid Craving

for Opioid Use Disorder

1 location in Wernersville

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 75

Code: NCT07128524·Phase 2·Recruiting·Listed Aug 2025

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A Trial to Evaluate Safety, Tolerability, and Preliminary Efficacy of Misetionamide (GP-2250) as Monotherapy or in Combination With Gemcitabine

for Ovarian Cancer

Sites in Phildelphia +3 more locations

Sponsor: Persevere Therapeutics Inc.

Sex: Female·Age: 18+

Code: NCT03854110·Phase 1·Recruiting·Listed Feb 2019

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Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)

Sites in Philadelphia +4 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06535607·Phase 2·Recruiting·Listed Aug 2024

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Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

for Asthma

Drug: Depemokimab

Sites in Philadelphia, DuBois +6 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06979323·Phase 3·Recruiting·Listed May 2025

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Product Surveillance Registry

for Cardiac Rhythm Disorders

Sites in Philadelphia, Pittsburgh +127 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting·Listed Feb 2012

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

Sites in Philadelphia, Hershey +111 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting·Listed Mar 2024

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Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

for APOL1-Mediated Kidney Disease

Sites in Philadelphia, Butler +76 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT06824987·Phase 2·Recruiting·Listed Feb 2025

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AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

for Lymphoma

Sites in Philadelphia +6 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT06137144·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

Sites in Philadelphia, Hershey +146 more locations

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting·Listed Jun 2023

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Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

for Delayed Graft Function

Sites in Philadelphia +29 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06830798·Phase 3·Recruiting·Listed Feb 2025

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A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for HER2-positive Gastric Cancer

Drug: Rilvegostomig

Sites in Philadelphia +44 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06764875·Phase 3·Recruiting·Listed Jan 2025

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A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

1 location in Erie

Sponsor: Kriya Therapeutics, Inc.

Sex: All·Age: 55 - 80

Code: NCT06765980·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

for Solid Tumor, Adult

Sites in Philadelphia +8 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06554795·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

Sites in Philadelphia +3 more locations

Sponsor: Molecure S.A.

Sex: All·Age: 18+

Code: NCT06205121·Phase 2·Recruiting·Listed Jan 2024

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Philadelphia +35 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

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A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for Polymyositis, Dermatomyositis

Sites in Philadelphia, Pittsburgh +32 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06455449·Phase 3·Recruiting·Listed Jun 2024

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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for Neoplasms, Head and Neck

Drug: Dostarlimab

Sites in Philadelphia, Pittsburgh +29 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06256588·Phase 3·Recruiting·Listed Feb 2024

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A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for Non-obstructive Hypertrophic Cardiomyopathy

Sites in Philadelphia +21 more locations

Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07023614·Phase 2·Recruiting·Listed Jun 2025

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A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

Sites in Philadelphia +13 more locations

Sponsor: Xentria, Inc.

Sex: All·Age: 18 - 80

Code: NCT05890729·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in Pittsburgh +26 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06417814·Phase 3·Recruiting·Listed May 2024

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Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

for Eosinophilic Asthma

Sites in DuBois +30 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12 - 75

Code: NCT06750289·Phase 3·Recruiting·Listed Dec 2024

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Rocket Study: A Study to Characterize Biomarkers and Disease Progression in Participants With Pelizaeus-Merzbacher Disease

for Pelizaeus-Merzbacher Disease

Sites in Philadelphia +1 more location

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male·Age: 6 Months - 17

Code: NCT05659901·Recruiting·Listed Dec 2022

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

Sites in Philadelphia, DuBois +53 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06961214·Phase 3·Recruiting·Listed May 2025

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A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for Solid Tumor

Sites in Philadelphia +16 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06384807·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for Lung Diseases, Interstitial

Sites in Philadelphia +15 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06572384·Phase 3·Recruiting·Listed Aug 2024

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Study of AZD0754 in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Philadelphia +12 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT06267729·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

for Systemic Sclerosis Associated Interstitial Lung Disease

Sites in Philadelphia +23 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT05878717·Phase 2, Phase 3·Recruiting·Listed May 2023

Apply to this trial